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145 related items for PubMed ID: 14980615

  • 1. Interactions of the antibiotics neomycin B and chlortetracycline with the hammerhead ribozyme as studied by Zn2+-dependent RNA cleavage.
    Borda EJ, Sigurdsson ST.
    Bioorg Med Chem; 2004 Mar 01; 12(5):1023-8. PubMed ID: 14980615
    [Abstract] [Full Text] [Related]

  • 2. Antibiotic inhibition of RNA catalysis: neomycin B binds to the catalytic core of the td group I intron displacing essential metal ions.
    Hoch I, Berens C, Westhof E, Schroeder R.
    J Mol Biol; 1998 Sep 25; 282(3):557-69. PubMed ID: 9737922
    [Abstract] [Full Text] [Related]

  • 3. Structural investigation of a high-affinity MnII binding site in the hammerhead ribozyme by EPR spectroscopy and DFT calculations. Effects of neomycin B on metal-ion binding.
    Schiemann O, Fritscher J, Kisseleva N, Sigurdsson ST, Prisner TF.
    Chembiochem; 2003 Oct 06; 4(10):1057-65. PubMed ID: 14523924
    [Abstract] [Full Text] [Related]

  • 4. Zinc-dependent cleavage in the catalytic core of the hammerhead ribozyme: evidence for a pH-dependent conformational change.
    Borda EJ, Markley JC, Sigurdsson ST.
    Nucleic Acids Res; 2003 May 15; 31(10):2595-600. PubMed ID: 12736309
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of the self-cleavage reaction of the human hepatitis delta virus ribozyme by antibiotics.
    Rogers J, Chang AH, von Ahsen U, Schroeder R, Davies J.
    J Mol Biol; 1996 Jun 28; 259(5):916-25. PubMed ID: 8683594
    [Abstract] [Full Text] [Related]

  • 6. 2-Aminopurine as a real-time probe of enzymatic cleavage and inhibition of hammerhead ribozymes.
    Kirk SR, Luedtke NW, Tor Y.
    Bioorg Med Chem; 2001 Sep 28; 9(9):2295-301. PubMed ID: 11553468
    [Abstract] [Full Text] [Related]

  • 7. Fast cleavage kinetics of a natural hammerhead ribozyme.
    Canny MD, Jucker FM, Kellogg E, Khvorova A, Jayasena SD, Pardi A.
    J Am Chem Soc; 2004 Sep 08; 126(35):10848-9. PubMed ID: 15339162
    [Abstract] [Full Text] [Related]

  • 8. Spermine switches a Neurospora VS ribozyme from slow Cis cleavage to fast trans cleavage.
    Olive JE, Collins RA.
    Biochemistry; 1998 May 05; 37(18):6476-84. PubMed ID: 9572865
    [Abstract] [Full Text] [Related]

  • 9. Monovalent ion dependence of neomycin B binding to an RNA aptamer characterized by spectroscopic methods.
    Stampfl S, Lempradl A, Koehler G, Schroeder R.
    Chembiochem; 2007 Jul 09; 8(10):1137-45. PubMed ID: 17539031
    [Abstract] [Full Text] [Related]

  • 10. In vitro selection analysis of neomycin binding RNAs with a mutagenized pool of variants of the 16S rRNA decoding region.
    Famulok M, Hüttenhofer A.
    Biochemistry; 1996 Apr 09; 35(14):4265-70. PubMed ID: 8605174
    [Abstract] [Full Text] [Related]

  • 11. Antibiotic interactions with the hammerhead ribozyme:tetracyclines as a new class of hammerhead inhibitor.
    Murray JB, Arnold JR.
    Biochem J; 1996 Aug 01; 317 ( Pt 3)(Pt 3):855-60. PubMed ID: 8760373
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of the hammerhead ribozyme by neomycin.
    Stage TK, Hertel KJ, Uhlenbeck OC.
    RNA; 1995 Mar 01; 1(1):95-101. PubMed ID: 7489494
    [Abstract] [Full Text] [Related]

  • 13. Synthetic metallonucleases for RNA cleavage.
    Morrow JR, Iranzo O.
    Curr Opin Chem Biol; 2004 Apr 01; 8(2):192-200. PubMed ID: 15062781
    [Abstract] [Full Text] [Related]

  • 14. Neomycin inhibition of the hammerhead ribozyme involves ionic interactions.
    Clouet-d'Orval B, Stage TK, Uhlenbeck OC.
    Biochemistry; 1995 Sep 05; 34(35):11186-90. PubMed ID: 7669776
    [Abstract] [Full Text] [Related]

  • 15. Aminoglycoside binding to the hammerhead ribozyme: a general model for the interaction of cationic antibiotics with RNA.
    Hermann T, Westhof E.
    J Mol Biol; 1998 Mar 13; 276(5):903-12. PubMed ID: 9566195
    [Abstract] [Full Text] [Related]

  • 16. Photocrosslinking detects a compact, active structure of the hammerhead ribozyme.
    Heckman JE, Lambert D, Burke JM.
    Biochemistry; 2005 Mar 22; 44(11):4148-56. PubMed ID: 15766242
    [Abstract] [Full Text] [Related]

  • 17. Solvent protection of the hammerhead ribozyme in the ground state: evidence for a cation-assisted conformational change leading to catalysis.
    Hampel KJ, Burke JM.
    Biochemistry; 2003 Apr 22; 42(15):4421-9. PubMed ID: 12693938
    [Abstract] [Full Text] [Related]

  • 18. Probing general acid catalysis in the hammerhead ribozyme.
    Thomas JM, Perrin DM.
    J Am Chem Soc; 2009 Jan 28; 131(3):1135-43. PubMed ID: 19154176
    [Abstract] [Full Text] [Related]

  • 19. Model for general acid-base catalysis by the hammerhead ribozyme: pH-activity relationships of G8 and G12 variants at the putative active site.
    Han J, Burke JM.
    Biochemistry; 2005 May 31; 44(21):7864-70. PubMed ID: 15910000
    [Abstract] [Full Text] [Related]

  • 20. Role of an active site guanine in hairpin ribozyme catalysis probed by exogenous nucleobase rescue.
    Kuzmin YI, Da Costa CP, Fedor MJ.
    J Mol Biol; 2004 Jul 02; 340(2):233-51. PubMed ID: 15201049
    [Abstract] [Full Text] [Related]

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