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Journal Abstract Search

168 related items for PubMed ID: 14985071

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  • 5. Simvastatin reduces lipoprotein-associated phospholipase A2 in lipopolysaccharide-stimulated human monocyte-derived macrophages through inhibition of the mevalonate-geranylgeranyl pyrophosphate-RhoA-p38 mitogen-activated protein kinase pathway.
    Song JX, Ren JY, Chen H.
    J Cardiovasc Pharmacol; 2011 Feb; 57(2):213-22. PubMed ID: 21052011
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  • 7. Role of RhoA inactivation in reduced cell proliferation of human airway smooth muscle by simvastatin.
    Takeda N, Kondo M, Ito S, Ito Y, Shimokata K, Kume H.
    Am J Respir Cell Mol Biol; 2006 Dec; 35(6):722-9. PubMed ID: 16858009
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  • 8. Simvastatin potentiates tumor necrosis factor alpha-mediated apoptosis of human vascular endothelial cells via the inhibition of the geranylgeranylation of RhoA.
    Tang D, Park HJ, Georgescu SP, Sebti SM, Hamilton AD, Galper JB.
    Life Sci; 2006 Sep 05; 79(15):1484-92. PubMed ID: 16740276
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  • 10. Decreased C-reactive protein-induced resistin production in human monocytes by simvastatin.
    Hu WL, Qiao SB, Li JJ.
    Cytokine; 2007 Dec 05; 40(3):201-6. PubMed ID: 18023360
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  • 11. Simvastatin inhibits MMP-9 secretion from human saphenous vein smooth muscle cells by inhibiting the RhoA/ROCK pathway and reducing MMP-9 mRNA levels.
    Turner NA, O'Regan DJ, Ball SG, Porter KE.
    FASEB J; 2005 May 05; 19(7):804-6. PubMed ID: 15728660
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  • 12. Inhibition of RhoA/Rho-kinase pathway suppresses the expression of type I collagen induced by TGF-beta2 in human retinal pigment epithelial cells.
    Itoh Y, Kimoto K, Imaizumi M, Nakatsuka K.
    Exp Eye Res; 2007 Mar 05; 84(3):464-72. PubMed ID: 17217948
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  • 14. Statins suppress THP-1 cell migration and secretion of matrix metalloproteinase 9 by inhibiting geranylgeranylation.
    Wong B, Lumma WC, Smith AM, Sisko JT, Wright SD, Cai TQ.
    J Leukoc Biol; 2001 Jun 05; 69(6):959-62. PubMed ID: 11404382
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  • 16. Simvastatin inhibits production of interleukin 6 (IL-6) and IL-8 and cell proliferation induced by tumor necrosis factor-alpha in fibroblast-like synoviocytes from patients with rheumatoid arthritis.
    Yokota K, Miyazaki T, Hirano M, Akiyama Y, Mimura T.
    J Rheumatol; 2006 Mar 05; 33(3):463-71. PubMed ID: 16511915
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  • 17. Inhibition of the RhoA/Rho-associated, coiled-coil-containing protein kinase-1 pathway is involved in the therapeutic effects of simvastatin on pulmonary arterial hypertension.
    Liu WH, Xu XH, Luo Q, Zhang HL, Wang Y, Xi QY, Zhao ZH, Liu ZH.
    Clin Exp Hypertens; 2018 Mar 05; 40(3):224-230. PubMed ID: 29319354
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  • 18. Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway.
    Yamashita M, Otsuka F, Mukai T, Otani H, Inagaki K, Miyoshi T, Goto J, Yamamura M, Makino H.
    J Endocrinol; 2008 Mar 05; 196(3):601-13. PubMed ID: 18310456
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  • 19. Statins suppress MMP2 secretion via inactivation of RhoA/ROCK pathway in pulmonary vascular smooth muscles cells.
    Li M, Li Z, Sun X.
    Eur J Pharmacol; 2008 Sep 04; 591(1-3):219-23. PubMed ID: 18619957
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  • 20. HMG-CoA reductase inhibitor fluvastatin prevents angiotensin II-induced cardiac hypertrophy via Rho kinase and inhibition of cyclin D1.
    Morikawa-Futamatsu K, Adachi S, Maejima Y, Tamamori-Adachi M, Suzuki J, Kitajima S, Ito H, Isobe M.
    Life Sci; 2006 Aug 29; 79(14):1380-90. PubMed ID: 16712874
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