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Journal Abstract Search

151 related items for PubMed ID: 14985806

  • 1. Synthesis and full characterisation of 6-chloro-2-iodopurine, a template for the functionalisation of purines.
    Taddei D, Kilian P, Slawin AM, Derek Woollins J.
    Org Biomol Chem; 2004 Mar 07; 2(5):665-70. PubMed ID: 14985806
    [Abstract] [Full Text] [Related]

  • 2. Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases.
    Legraverend M, Ludwig O, Bisagni E, Leclerc S, Meijer L.
    Bioorg Med Chem Lett; 1998 Apr 07; 8(7):793-8. PubMed ID: 9871543
    [Abstract] [Full Text] [Related]

  • 3. Rapid identification of the pharmacophore in a peptoid inhibitor of the proteasome regulatory particle.
    Lim HS, Archer CT, Kim YC, Hutchens T, Kodadek T.
    Chem Commun (Camb); 2008 Mar 07; (9):1064-6. PubMed ID: 18292891
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological evaluation of new imidazole, pyrimidine, and purine derivatives and analogs as inhibitors of xanthine oxidase.
    Biagi G, Costantini A, Costantino L, Giorgi I, Livi O, Pecorari P, Rinaldi M, Scartoni V.
    J Med Chem; 1996 Jun 21; 39(13):2529-35. PubMed ID: 8691450
    [Abstract] [Full Text] [Related]

  • 5. The purines: potent and versatile small molecule inhibitors and modulators of key biological targets.
    Legraverend M, Grierson DS.
    Bioorg Med Chem; 2006 Jun 15; 14(12):3987-4006. PubMed ID: 16503144
    [Abstract] [Full Text] [Related]

  • 6. Regiospecific N9 alkylation of 6-(heteroaryl)purines: shielding of N7 by a proximal heteroaryl C-H1.
    Zhong M, Robins MJ.
    J Org Chem; 2006 Nov 10; 71(23):8901-6. PubMed ID: 17081021
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, characterization and assessment of the cytotoxic properties of cis and trans-[Pd(L)(2)Cl(2)] complexes involving 6-benzylamino-9-isopropylpurine derivatives.
    Trávnícek Z, Szucová L, Popa I.
    J Inorg Biochem; 2007 Mar 10; 101(3):477-92. PubMed ID: 17208304
    [Abstract] [Full Text] [Related]

  • 8. Structure and synthesis of 6-(substituted-imidazol-1-yl)purines: versatile substrates for regiospecific alkylation and glycosylation at N9.
    Zhong M, Nowak I, Cannon JF, Robins MJ.
    J Org Chem; 2006 May 26; 71(11):4216-21. PubMed ID: 16709063
    [Abstract] [Full Text] [Related]

  • 9. Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue.
    Pereira HM, Berdini V, Cleasby A, Garratt RC.
    FEBS Lett; 2007 Oct 30; 581(26):5082-6. PubMed ID: 17927987
    [Abstract] [Full Text] [Related]

  • 10. 2-Benzimidazolyl-9-(chroman-4-yl)-purinone derivatives as JAK3 inhibitors.
    Cole AG, Bohnstedt AC, Paradkar V, Kingsbury C, Quintero JG, Park H, Lu Y, You M, Neagu I, Diller DJ, Letourneau JJ, Shao Y, James RA, Riviello CM, Ho KK, Lin TH, Wang B, Appell KC, Sills M, Quadros E, Kimble EF, Ohlmeyer MH, Webb ML.
    Bioorg Med Chem Lett; 2009 Dec 01; 19(23):6788-92. PubMed ID: 19836234
    [Abstract] [Full Text] [Related]

  • 11. Synthesis, structure, and antimycobacterial activity of 6-[1(3H)-isobenzofuranylidenemethyl]purines and analogs.
    Braendvang M, Bakken V, Gundersen LL.
    Bioorg Med Chem; 2009 Sep 15; 17(18):6512-6. PubMed ID: 19709890
    [Abstract] [Full Text] [Related]

  • 12. Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds.
    Dalgarno D, Stehle T, Narula S, Schelling P, van Schravendijk MR, Adams S, Andrade L, Keats J, Ram M, Jin L, Grossman T, MacNeil I, Metcalf C, Shakespeare W, Wang Y, Keenan T, Sundaramoorthi R, Bohacek R, Weigele M, Sawyer T.
    Chem Biol Drug Des; 2006 Jan 15; 67(1):46-57. PubMed ID: 16492148
    [Abstract] [Full Text] [Related]

  • 13. 2-Chloro-6-(2-furyl)-9-(4-methoxybenzyl)-9H-purine.
    Braendvang M, Gundersen LL.
    Acta Crystallogr C; 2007 May 15; 63(Pt 5):o274-6. PubMed ID: 17478910
    [Abstract] [Full Text] [Related]

  • 14. Structure-guided discovery of cyclin-dependent kinase inhibitors.
    Fischmann TO, Hruza A, Duca JS, Ramanathan L, Mayhood T, Windsor WT, Le HV, Guzi TJ, Dwyer MP, Paruch K, Doll RJ, Lees E, Parry D, Seghezzi W, Madison V.
    Biopolymers; 2008 May 15; 89(5):372-9. PubMed ID: 17937404
    [Abstract] [Full Text] [Related]

  • 15. Synthesis of branched 9-[2-(2-phosphonoethoxy)ethyl]purines as a new class of acyclic nucleoside phosphonates which inhibit Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.
    Hocková D, Holý A, Masojídková M, Keough DT, de Jersey J, Guddat LW.
    Bioorg Med Chem; 2009 Sep 01; 17(17):6218-32. PubMed ID: 19666228
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and biological activity of 2-anilino-4-(1H-pyrrol-3-yl) pyrimidine CDK inhibitors.
    Wang S, Wood G, Meades C, Griffiths G, Midgley C, McNae I, McInnes C, Anderson S, Jackson W, Mezna M, Yuill R, Walkinshaw M, Fischer PM.
    Bioorg Med Chem Lett; 2004 Aug 16; 14(16):4237-40. PubMed ID: 15261277
    [Abstract] [Full Text] [Related]

  • 17. Exploring 9-benzyl purines as inhibitors of glutamate racemase (MurI) in Gram-positive bacteria.
    Geng B, Breault G, Comita-Prevoir J, Petrichko R, Eyermann C, Lundqvist T, Doig P, Gorseth E, Noonan B.
    Bioorg Med Chem Lett; 2008 Aug 01; 18(15):4368-72. PubMed ID: 18614367
    [Abstract] [Full Text] [Related]

  • 18. Discovery of potent inhibitors of dihydroneopterin aldolase using CrystaLEAD high-throughput X-ray crystallographic screening and structure-directed lead optimization.
    Sanders WJ, Nienaber VL, Lerner CG, McCall JO, Merrick SM, Swanson SJ, Harlan JE, Stoll VS, Stamper GF, Betz SF, Condroski KR, Meadows RP, Severin JM, Walter KA, Magdalinos P, Jakob CG, Wagner R, Beutel BA.
    J Med Chem; 2004 Mar 25; 47(7):1709-18. PubMed ID: 15027862
    [Abstract] [Full Text] [Related]

  • 19. The effect of novel [3-fluoro-(2-phosphonoethoxy)propyl]purines on the inhibition of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases.
    Baszczyňski O, Hocková D, Janeba Z, Holý A, Jansa P, Dračínský M, Keough DT, Guddat LW.
    Eur J Med Chem; 2013 Sep 25; 67():81-9. PubMed ID: 23850568
    [Abstract] [Full Text] [Related]

  • 20. Ferrocene-modified purines as potential electrochemical markers: synthesis, crystal structures, electrochemistry and cytostatic activity of (ferrocenylethynyl)- and (ferrocenylethyl)purines.
    Hocek M, Stepnicka P, Ludvík J, Císarová I, Votruba I, Reha D, Hobza P.
    Chemistry; 2004 Apr 19; 10(8):2058-66. PubMed ID: 15079846
    [Abstract] [Full Text] [Related]

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