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144 related items for PubMed ID: 14990989

  • 1. Niban gene is commonly expressed in the renal tumors: a new candidate marker for renal carcinogenesis.
    Adachi H, Majima S, Kon S, Kobayashi T, Kajino K, Mitani H, Hirayama Y, Shiina H, Igawa M, Hino O.
    Oncogene; 2004 Apr 22; 23(19):3495-500. PubMed ID: 14990989
    [Abstract] [Full Text] [Related]

  • 2. Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors.
    Kenerson HL, Aicher LD, True LD, Yeung RS.
    Cancer Res; 2002 Oct 15; 62(20):5645-50. PubMed ID: 12384518
    [Abstract] [Full Text] [Related]

  • 3. The transcriptional profile of the kidney in Tsc2 heterozygous mutant Long Evans (Eker) rats compared to wild-type.
    Sen B, Wolf DC, Hester SD.
    Mutat Res; 2004 May 18; 549(1-2):213-24. PubMed ID: 15120972
    [Abstract] [Full Text] [Related]

  • 4. Efficacy of a rapamycin analog (CCI-779) and IFN-gamma in tuberous sclerosis mouse models.
    Lee L, Sudentas P, Donohue B, Asrican K, Worku A, Walker V, Sun Y, Schmidt K, Albert MS, El-Hashemite N, Lader AS, Onda H, Zhang H, Kwiatkowski DJ, Dabora SL.
    Genes Chromosomes Cancer; 2005 Mar 18; 42(3):213-27. PubMed ID: 15578690
    [Abstract] [Full Text] [Related]

  • 5. Presence of a modifier gene(s) affecting early renal carcinogenesis in the Tsc2 mutant (Eker) rat model.
    Kikuchi Y, Sudo A, Mitani H, Hino O.
    Int J Oncol; 2004 Jan 18; 24(1):75-80. PubMed ID: 14654943
    [Abstract] [Full Text] [Related]

  • 6. Presence of potent transcriptional activation domains in the predisposing tuberous sclerosis (Tsc2) gene product of the Eker rat model.
    Tsuchiya H, Orimoto K, Kobayashi K, Hino O.
    Cancer Res; 1996 Feb 01; 56(3):429-33. PubMed ID: 8564946
    [Abstract] [Full Text] [Related]

  • 7. Effects of rapamycin in the Eker rat model of tuberous sclerosis complex.
    Kenerson H, Dundon TA, Yeung RS.
    Pediatr Res; 2005 Jan 01; 57(1):67-75. PubMed ID: 15557109
    [Abstract] [Full Text] [Related]

  • 8. Overexpression of members of the AP-1 transcriptional factor family from an early stage of renal carcinogenesis and inhibition of cell growth by AP-1 gene antisense oligonucleotides in the Tsc2 gene mutant (Eker) rat model.
    Urakami S, Tsuchiya H, Orimoto K, Kobayashi T, Igawa M, Hino O.
    Biochem Biophys Res Commun; 1997 Dec 08; 241(1):24-30. PubMed ID: 9405228
    [Abstract] [Full Text] [Related]

  • 9. Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice.
    Kobayashi T, Minowa O, Kuno J, Mitani H, Hino O, Noda T.
    Cancer Res; 1999 Mar 15; 59(6):1206-11. PubMed ID: 10096549
    [Abstract] [Full Text] [Related]

  • 10. N-terminal hamartin-binding and C-terminal GAP domain of tuberin can separate in vivo.
    Momose S, Kobayashi T, Tada N, Itoyama S, Hino O.
    Biochem Biophys Res Commun; 2007 May 11; 356(3):693-8. PubMed ID: 17379185
    [Abstract] [Full Text] [Related]

  • 11. Mapping and determination of the cDNA sequence of the Erc gene preferentially expressed in renal cell carcinoma in the Tsc2 gene mutant (Eker) rat model.
    Yamashita Y, Yokoyama M, Kobayashi E, Takai S, Hino O.
    Biochem Biophys Res Commun; 2000 Aug 18; 275(1):134-40. PubMed ID: 10944454
    [Abstract] [Full Text] [Related]

  • 12. The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition.
    Shiono M, Kobayashi T, Takahashi R, Sun G, Abe M, Zhang D, Wang L, Piao X, Takagi Y, Mineki R, Taka H, Tada N, Sonobe S, Momose S, Ueda M, Hino O.
    Oncogene; 2008 Nov 06; 27(52):6690-7. PubMed ID: 18695678
    [Abstract] [Full Text] [Related]

  • 13. The mTOR/S6K signalling pathway: the role of the TSC1/2 tumour suppressor complex and the proto-oncogene Rheb.
    Nobukini T, Thomas G.
    Novartis Found Symp; 2004 Nov 06; 262():148-54; discussion 154-9, 265-8. PubMed ID: 15562827
    [Abstract] [Full Text] [Related]

  • 14. Early detection of Knudson's two-hits in preneoplastic renal cells of the Eker rat model by the laser microdissection procedure.
    Kubo Y, Klimek F, Kikuchi Y, Bannasch P, Hino O.
    Cancer Res; 1995 Mar 01; 55(5):989-90. PubMed ID: 7867009
    [Abstract] [Full Text] [Related]

  • 15. Selective inhibition of growth of tuberous sclerosis complex 2 null cells by atorvastatin is associated with impaired Rheb and Rho GTPase function and reduced mTOR/S6 kinase activity.
    Finlay GA, Malhowski AJ, Liu Y, Fanburg BL, Kwiatkowski DJ, Toksoz D.
    Cancer Res; 2007 Oct 15; 67(20):9878-86. PubMed ID: 17942919
    [Abstract] [Full Text] [Related]

  • 16. A novel gene "Niban" upregulated in renal carcinogenesis: cloning by the cDNA-amplified fragment length polymorphism approach.
    Majima S, Kajino K, Fukuda T, Otsuka F, Hino O.
    Jpn J Cancer Res; 2000 Sep 15; 91(9):869-74. PubMed ID: 11011112
    [Abstract] [Full Text] [Related]

  • 17. Identification of cDNAs induced by the tumor suppressor Tsc2 gene using a conditional expression system in Tsc2 mutant (Eker) rat renal carcinoma cells.
    Orimoto K, Tsuchiya H, Sakurai J, Nishizawa M, Hino O.
    Biochem Biophys Res Commun; 1998 Jun 29; 247(3):728-33. PubMed ID: 9647762
    [Abstract] [Full Text] [Related]

  • 18. Platelet-derived growth factor-induced p42/44 mitogen-activated protein kinase activation and cellular growth is mediated by reactive oxygen species in the absence of TSC2/tuberin.
    Finlay GA, Thannickal VJ, Fanburg BL, Kwiatkowski DJ.
    Cancer Res; 2005 Dec 01; 65(23):10881-90. PubMed ID: 16322235
    [Abstract] [Full Text] [Related]

  • 19. Changes in gene expression during chemical-induced nephrocarcinogenicity in the Eker rat.
    Patel SK, Ma N, Monks TJ, Lau SS.
    Mol Carcinog; 2003 Nov 01; 38(3):141-54. PubMed ID: 14587099
    [Abstract] [Full Text] [Related]

  • 20. Mutation in TSC2 and activation of mammalian target of rapamycin signalling pathway in renal angiomyolipoma.
    El-Hashemite N, Zhang H, Henske EP, Kwiatkowski DJ.
    Lancet; 2003 Apr 19; 361(9366):1348-9. PubMed ID: 12711473
    [Abstract] [Full Text] [Related]

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