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Journal Abstract Search

163 related items for PubMed ID: 14993705

  • 1. Rapid screening for HIV-1 protease inhibitor leads through X-ray diffraction.
    Pillai B, Kannan KK, Bhat SV, Hosur MV.
    Acta Crystallogr D Biol Crystallogr; 2004 Mar; 60(Pt 3):594-6. PubMed ID: 14993705
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  • 2. 1.8A X-ray structure of C95M/C1095F double mutant of tethered HIV-1 protease dimer complexed with acetyl pepstatin.
    Prashar V, Hosur MV.
    Biochem Biophys Res Commun; 2004 Oct 29; 323(4):1229-35. PubMed ID: 15451428
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  • 3. Inhibitor binding at the protein interface in crystals of a HIV-1 protease complex.
    Brynda J, Rezácová P, Fábry M, Horejsí M, Stouracová R, Soucek M, Hradílek M, Konvalinka J, Sedlácek J.
    Acta Crystallogr D Biol Crystallogr; 2004 Nov 29; 60(Pt 11):1943-8. PubMed ID: 15502300
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  • 4. Structural role of the 30's loop in determining the ligand specificity of the human immunodeficiency virus protease.
    Swairjo MA, Towler EM, Debouck C, Abdel-Meguid SS.
    Biochemistry; 1998 Aug 04; 37(31):10928-36. PubMed ID: 9692985
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  • 5. HIV-1 protease mutations and inhibitor modifications monitored on a series of complexes. Structural basis for the effect of the A71V mutation on the active site.
    Skalova T, Dohnalek J, Duskova J, Petrokova H, Hradílek M, Soucek M, Konvalinka J, Hasek J.
    J Med Chem; 2006 Sep 21; 49(19):5777-84. PubMed ID: 16970402
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  • 7. Relation between sequence and structure of HIV-1 protease inhibitor complexes: a model system for the analysis of protein flexibility.
    Zoete V, Michielin O, Karplus M.
    J Mol Biol; 2002 Jan 04; 315(1):21-52. PubMed ID: 11771964
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  • 11. Comparative studies on inhibitors of HIV protease: a target for drug design.
    Jayaraman S, Shah K.
    In Silico Biol; 2008 Jan 04; 8(5-6):427-47. PubMed ID: 19374129
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  • 12. On the role of the R configuration of the reaction-intermediate isostere in HIV-1 protease-inhibitor binding: X-ray structure at 2.0 A resolution.
    Dusková J, Dohnálek J, Skálová T, Petroková H, Vondrácková E, Hradílek M, Konvalinka J, Soucek M, Brynda J, Fábry M, Sedlácek J, Hasek J.
    Acta Crystallogr D Biol Crystallogr; 2006 May 04; 62(Pt 5):489-97. PubMed ID: 16627941
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  • 14. Discovery of HIV-1 protease inhibitors with picomolar affinities incorporating N-aryl-oxazolidinone-5-carboxamides as novel P2 ligands.
    Ali A, Reddy GS, Cao H, Anjum SG, Nalam MN, Schiffer CA, Rana TM.
    J Med Chem; 2006 Dec 14; 49(25):7342-56. PubMed ID: 17149864
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  • 15. Structural and kinetic analysis of pyrrolidine-based inhibitors of the drug-resistant Ile84Val mutant of HIV-1 protease.
    Böttcher J, Blum A, Heine A, Diederich WE, Klebe G.
    J Mol Biol; 2008 Nov 07; 383(2):347-57. PubMed ID: 18692068
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