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714 related items for PubMed ID: 14996842

  • 1. Induction of gp130-related cytokines and activation of JAK2/STAT3 pathway in astrocytes precedes up-regulation of glial fibrillary acidic protein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of neurodegeneration: key signaling pathway for astrogliosis in vivo?
    Sriram K, Benkovic SA, Hebert MA, Miller DB, O'Callaghan JP.
    J Biol Chem; 2004 May 07; 279(19):19936-47. PubMed ID: 14996842
    [Abstract] [Full Text] [Related]

  • 2. The MAP kinase cascade is activated prior to the induction of gliosis in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) model of dopaminergic neurotoxicity.
    O'Callaghan JP, Martin PM, Mass MJ.
    Ann N Y Acad Sci; 1998 May 30; 844():40-9. PubMed ID: 9668663
    [Abstract] [Full Text] [Related]

  • 3. Alterations in Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signaling in patients with end-stage dilated cardiomyopathy.
    Podewski EK, Hilfiker-Kleiner D, Hilfiker A, Morawietz H, Lichtenberg A, Wollert KC, Drexler H.
    Circulation; 2003 Feb 18; 107(6):798-802. PubMed ID: 12591746
    [Abstract] [Full Text] [Related]

  • 4. JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells.
    De Vos J, Jourdan M, Tarte K, Jasmin C, Klein B.
    Br J Haematol; 2000 Jun 18; 109(4):823-8. PubMed ID: 10929036
    [Abstract] [Full Text] [Related]

  • 5. Activation of the Jak-Stat- and MAPK-pathways by oncostatin M is not sufficient to cause growth inhibition of human glioma cells.
    Halfter H, Postert C, Friedrich M, Ringelstein EB, Stögbauer F.
    Brain Res Mol Brain Res; 2000 Sep 15; 80(2):198-206. PubMed ID: 11038252
    [Abstract] [Full Text] [Related]

  • 6. The Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway.
    Park JI, Strock CJ, Ball DW, Nelkin BD.
    Mol Cell Biol; 2003 Jan 15; 23(2):543-54. PubMed ID: 12509453
    [Abstract] [Full Text] [Related]

  • 7. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.
    Schaper F, Gendo C, Eck M, Schmitz J, Grimm C, Anhuf D, Kerr IM, Heinrich PC.
    Biochem J; 1998 Nov 01; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795
    [Abstract] [Full Text] [Related]

  • 8. Src family kinase-independent signal transduction and gene induction by leukemia inhibitory factor.
    Laszlo GS, Nathanson NM.
    J Biol Chem; 2003 Jul 25; 278(30):27750-7. PubMed ID: 12764151
    [Abstract] [Full Text] [Related]

  • 9. Thrombopoietin, but not cytokines binding to gp130 protein-coupled receptors, activates MAPKp42/44, AKT, and STAT proteins in normal human CD34+ cells, megakaryocytes, and platelets.
    Majka M, Ratajczak J, Villaire G, Kubiczek K, Marquez LA, Janowska-Wieczorek A, Ratajczak MZ.
    Exp Hematol; 2002 Jul 25; 30(7):751-60. PubMed ID: 12135673
    [Abstract] [Full Text] [Related]

  • 10. Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells.
    Kim H, Baumann H.
    Mol Cell Biol; 1999 Aug 25; 19(8):5326-38. PubMed ID: 10409724
    [Abstract] [Full Text] [Related]

  • 11. Peripheral but not central axotomy induces changes in Janus kinases (JAK) and signal transducers and activators of transcription (STAT).
    Schwaiger FW, Hager G, Schmitt AB, Horvat A, Hager G, Streif R, Spitzer C, Gamal S, Breuer S, Brook GA, Nacimiento W, Kreutzberg GW.
    Eur J Neurosci; 2000 Apr 25; 12(4):1165-76. PubMed ID: 10762348
    [Abstract] [Full Text] [Related]

  • 12. Recapitulation of cell signaling events associated with astrogliosis using the brain slice preparation.
    Damiani CL, O'Callaghan JP.
    J Neurochem; 2007 Feb 25; 100(3):720-6. PubMed ID: 17176261
    [Abstract] [Full Text] [Related]

  • 13. Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway.
    Bonni A, Sun Y, Nadal-Vicens M, Bhatt A, Frank DA, Rozovsky I, Stahl N, Yancopoulos GD, Greenberg ME.
    Science; 1997 Oct 17; 278(5337):477-83. PubMed ID: 9334309
    [Abstract] [Full Text] [Related]

  • 14. Activation of JAK-STAT and MAP kinases by leukemia inhibitory factor through gp130 in cardiac myocytes.
    Kunisada K, Hirota H, Fujio Y, Matsui H, Tani Y, Yamauchi-Takihara K, Kishimoto T.
    Circulation; 1996 Nov 15; 94(10):2626-32. PubMed ID: 8921810
    [Abstract] [Full Text] [Related]

  • 15. Directly linked soluble IL-6 receptor-IL-6 fusion protein induces astrocyte differentiation from neuroepithelial cells via activation of STAT3.
    Takizawa T, Yanagisawa M, Ochiai W, Yasukawa K, Ishiguro T, Nakashima K, Taga T.
    Cytokine; 2001 Mar 07; 13(5):272-9. PubMed ID: 11243705
    [Abstract] [Full Text] [Related]

  • 16. Differential inhibition of IL-6-type cytokine-induced STAT activation by PMA.
    Terstegen L, Maassen BG, Radtke S, Behrmann I, Schaper F, Heinrich PC, Graeve L, Gatsios P.
    FEBS Lett; 2000 Jul 28; 478(1-2):100-4. PubMed ID: 10922477
    [Abstract] [Full Text] [Related]

  • 17. gp130-Dependent signalling pathway is not enhanced in gp130 transgenic heart after LIF stimulation.
    Tone E, Kunisada K, Kumanogoh A, Negoro S, Funamoto M, Osugi T, Kishimoto T, Yamauchi-Takihara K.
    Cytokine; 2000 Oct 28; 12(10):1512-8. PubMed ID: 11023666
    [Abstract] [Full Text] [Related]

  • 18. Induction of JAB/SOCS-1/SSI-1 and CIS3/SOCS-3/SSI-3 is involved in gp130 resistance in cardiovascular system in rat treated with cardiotrophin-1 in vivo.
    Hamanaka I, Saito Y, Yasukawa H, Kishimoto I, Kuwahara K, Miyamoto Y, Harada M, Ogawa E, Kajiyama N, Takahashi N, Izumi T, Kawakami R, Masuda I, Yoshimura A, Nakao K.
    Circ Res; 2001 Apr 13; 88(7):727-32. PubMed ID: 11304496
    [Abstract] [Full Text] [Related]

  • 19. Protein phosphorylation cascades associated with methamphetamine-induced glial activation.
    Hebert MA, O'Callaghan JP.
    Ann N Y Acad Sci; 2000 Sep 13; 914():238-62. PubMed ID: 11085325
    [Abstract] [Full Text] [Related]

  • 20. Oncostatin M-induced matrix metalloproteinase and tissue inhibitor of metalloproteinase-3 genes expression in chondrocytes requires Janus kinase/STAT signaling pathway.
    Li WQ, Dehnade F, Zafarullah M.
    J Immunol; 2001 Mar 01; 166(5):3491-8. PubMed ID: 11207308
    [Abstract] [Full Text] [Related]

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