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187 related items for PubMed ID: 15005884

  • 1. Studies on 1-arylpiperazine derivatives with affinity for rat 5-HT7 and 5-HT1A receptors.
    Leopoldo M, Berardi F, Colabufo NA, Contino M, Lacivita E, Perrone R, Tortorella V.
    J Pharm Pharmacol; 2004 Feb; 56(2):247-55. PubMed ID: 15005884
    [Abstract] [Full Text] [Related]

  • 2. Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
    Leopoldo M, Berardi F, Colabufo NA, Contino M, Lacivita E, Niso M, Perrone R, Tortorella V.
    J Med Chem; 2004 Dec 16; 47(26):6616-24. PubMed ID: 15588097
    [Abstract] [Full Text] [Related]

  • 3. Structure-activity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a class of 5-HT7 receptor agents. 2.
    Leopoldo M, Lacivita E, Contino M, Colabufo NA, Berardi F, Perrone R.
    J Med Chem; 2007 Aug 23; 50(17):4214-21. PubMed ID: 17649988
    [Abstract] [Full Text] [Related]

  • 4. New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation.
    Jurczyk S, Kołaczkowski M, Maryniak E, Zajdel P, Pawłowski M, Tatarczyńska E, Kłodzińska A, Chojnacka-Wójcik E, Bojarski AJ, Charakchieva-Minol S, Duszyńska B, Nowak G, Maciag D.
    J Med Chem; 2004 May 06; 47(10):2659-66. PubMed ID: 15115407
    [Abstract] [Full Text] [Related]

  • 5. 2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxamides with selective affinity for the 5-HT(4) receptor: synthesis and structure-affinity and structure-activity relationships of a new series of partial agonist and antagonist derivatives.
    Tapia I, Alonso-Cires L, López-Tudanca PL, Mosquera R, Labeaga L, Innerárity A, Orjales A.
    J Med Chem; 1999 Jul 29; 42(15):2870-80. PubMed ID: 10425096
    [Abstract] [Full Text] [Related]

  • 6. Differential effects of the 5-hydroxytryptamine (5-HT)1A receptor inverse agonists Rec 27/0224 and Rec 27/0074 on electrophysiological responses to 5-HT1A receptor activation in rat dorsal raphe nucleus and hippocampus in vitro.
    Corradetti R, Mlinar B, Falsini C, Pugliese AM, Cilia A, Destefani C, Testa R.
    J Pharmacol Exp Ther; 2005 Oct 29; 315(1):109-17. PubMed ID: 15951403
    [Abstract] [Full Text] [Related]

  • 7. Design and synthesis of long-chain arylpiperazines with mixed affinity for serotonin transporter (SERT) and 5-HT(1A) receptor.
    Perrone R, Berardi F, Colabufo NA, Lacivita E, Larizza C, Leopoldo M, Tortorella V.
    J Pharm Pharmacol; 2005 Oct 29; 57(10):1319-27. PubMed ID: 16259761
    [Abstract] [Full Text] [Related]

  • 8. 1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.
    Bojarski AJ, Paluchowska MH, Duszyńska B, Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E.
    Bioorg Med Chem; 2005 Mar 15; 13(6):2293-303. PubMed ID: 15727878
    [Abstract] [Full Text] [Related]

  • 9. Benzimidazole derivatives. Part 5: design and synthesis of new benzimidazole-arylpiperazine derivatives acting as mixed 5-HT1A/5-HT3 ligands.
    López-Rodríguez ML, Benhamú B, Morcillo MJ, Tejada I, Avila D, Marco I, Schiapparelli L, Frechilla D, Del Río J.
    Bioorg Med Chem; 2004 Oct 01; 12(19):5181-91. PubMed ID: 15351401
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and structure-affinity relationships of 1-[omega-(4-aryl-1-piperazinyl)alkyl]-1-aryl ketones as 5-HT(7) receptor ligands.
    Perrone R, Berardi F, Colabufo NA, Lacivita E, Leopoldo M, Tortorella V.
    J Med Chem; 2003 Feb 13; 46(4):646-9. PubMed ID: 12570387
    [Abstract] [Full Text] [Related]

  • 11. Anxiolytic-like effect of a serotonergic ligand with high affinity for 5-HT1A, 5-HT2A and 5-HT3 receptors.
    Delgado M, Caicoya AG, Greciano V, Benhamú B, López-Rodríguez ML, Fernández-Alfonso MS, Pozo MA, Manzanares J, Fuentes JA.
    Eur J Pharmacol; 2005 Mar 21; 511(1):9-19. PubMed ID: 15777774
    [Abstract] [Full Text] [Related]

  • 12. New 5-hydroxytryptamine(1A) receptor ligands containing a norbornene nucleus: synthesis and in vitro pharmacological evaluation.
    Fiorino F, Perissutti E, Severino B, Santagada V, Cirillo D, Terracciano S, Massarelli P, Bruni G, Collavoli E, Renner C, Caliendo G.
    J Med Chem; 2005 Aug 25; 48(17):5495-503. PubMed ID: 16107148
    [Abstract] [Full Text] [Related]

  • 13. Allosteric modulation of 5-HT(1A) receptors by zinc: Binding studies.
    Barrondo S, Sallés J.
    Neuropharmacology; 2009 Feb 25; 56(2):455-62. PubMed ID: 18951909
    [Abstract] [Full Text] [Related]

  • 14. The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines.
    Paluchowska MH, Bugno R, Duszyńska B, Tatarczyńska E, Nikiforuk A, Lenda T, Chojnacka-Wójcik E.
    Bioorg Med Chem; 2007 Nov 15; 15(22):7116-25. PubMed ID: 17825569
    [Abstract] [Full Text] [Related]

  • 15. Structure-intrinsic activity relationship studies in the group of 1-imido/amido substituted 4-(4-arylpiperazin-1-yl)cyclohexane derivatives; new, potent 5-HT1A receptor agents with anxiolytic- like activity.
    Bojarski AJ, Paluchowska MH, Duszyńska B, Bugno R, Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E.
    Bioorg Med Chem; 2006 Mar 01; 14(5):1391-402. PubMed ID: 16266808
    [Abstract] [Full Text] [Related]

  • 16. Synthesis of new serotonin 5-HT7 receptor ligands. Determinants of 5-HT7/5-HT1A receptor selectivity.
    Medina RA, Sallander J, Benhamú B, Porras E, Campillo M, Pardo L, López-Rodríguez ML.
    J Med Chem; 2009 Apr 23; 52(8):2384-92. PubMed ID: 19326916
    [Abstract] [Full Text] [Related]

  • 17. Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors.
    Cappelli A, Anzini M, Vomero S, Canullo L, Mennuni L, Makovec F, Doucet E, Hamon M, Menziani MC, De Benedetti PG, Bruni G, Romeo MR, Giorgi G, Donati A.
    J Med Chem; 1999 May 06; 42(9):1556-75. PubMed ID: 10229626
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and pharmacological characterization of a series of geometrically constrained 5-HT(2A/2C) receptor ligands.
    Chambers JJ, Parrish JC, Jensen NH, Kurrasch-Orbaugh DM, Marona-Lewicka D, Nichols DE.
    J Med Chem; 2003 Jul 31; 46(16):3526-35. PubMed ID: 12877591
    [Abstract] [Full Text] [Related]

  • 19. Novel derivatives of 2-pyridinemethylamine as selective, potent, and orally active agonists at 5-HT1A receptors.
    Vacher B, Bonnaud B, Funes P, Jubault N, Koek W, Assié MB, Cosi C, Kleven M.
    J Med Chem; 1999 May 06; 42(9):1648-60. PubMed ID: 10229633
    [Abstract] [Full Text] [Related]

  • 20. Bivalent ligand approach on 4-[2-(3-methoxyphenyl)ethyl]-1-(2-methoxyphenyl)piperazine: synthesis and binding affinities for 5-HT(7) and 5-HT(1A) receptors.
    Leopoldo M, Lacivita E, Colabufo NA, Niso M, Berardi F, Perrone R.
    Bioorg Med Chem; 2007 Aug 01; 15(15):5316-21. PubMed ID: 17517509
    [Abstract] [Full Text] [Related]

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