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Journal Abstract Search

195 related items for PubMed ID: 15007176

  • 1. Transgene-driven expression of the Doppel protein in Purkinje cells causes Purkinje cell degeneration and motor impairment.
    Anderson L, Rossi D, Linehan J, Brandner S, Weissmann C.
    Proc Natl Acad Sci U S A; 2004 Mar 09; 101(10):3644-9. PubMed ID: 15007176
    [Abstract] [Full Text] [Related]

  • 2. Doppel-induced Purkinje cell death is stoichiometrically abrogated by prion protein.
    Yamaguchi N, Sakaguchi S, Shigematsu K, Okimura N, Katamine S.
    Biochem Biophys Res Commun; 2004 Jul 09; 319(4):1247-52. PubMed ID: 15194501
    [Abstract] [Full Text] [Related]

  • 3. Deletion of N-terminal residues 23-88 from prion protein (PrP) abrogates the potential to rescue PrP-deficient mice from PrP-like protein/doppel-induced Neurodegeneration.
    Atarashi R, Nishida N, Shigematsu K, Goto S, Kondo T, Sakaguchi S, Katamine S.
    J Biol Chem; 2003 Aug 01; 278(31):28944-9. PubMed ID: 12759361
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  • 4. Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia.
    Flechsig E, Hegyi I, Leimeroth R, Zuniga A, Rossi D, Cozzio A, Schwarz P, Rülicke T, Götz J, Aguzzi A, Weissmann C.
    EMBO J; 2003 Jun 16; 22(12):3095-101. PubMed ID: 12805223
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  • 5. Doppel induces degeneration of cerebellar Purkinje cells independently of Bax.
    Dong J, Li A, Yamaguchi N, Sakaguchi S, Harris DA.
    Am J Pathol; 2007 Aug 16; 171(2):599-607. PubMed ID: 17569776
    [Abstract] [Full Text] [Related]

  • 6. Altered expression of type 1 inositol 1,4,5-trisphosphate receptor in the Ngsk Prnp deficient mice.
    Lee HP, Choi JK, Shin HY, Jeon YC, Jeong BH, Lee HG, Kim JI, Choi EK, Carp RI, Kim YS.
    Neuroscience; 2010 May 19; 167(3):799-808. PubMed ID: 20219645
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  • 7. Abnormal activation of glial cells in the brains of prion protein-deficient mice ectopically expressing prion protein-like protein, PrPLP/Dpl.
    Atarashi R, Sakaguchi S, Shigematsu K, Arima K, Okimura N, Yamaguchi N, Li A, Kopacek J, Katamine S.
    Mol Med; 2001 Dec 19; 7(12):803-9. PubMed ID: 11844868
    [Abstract] [Full Text] [Related]

  • 8. Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss.
    Silverman GL, Qin K, Moore RC, Yang Y, Mastrangelo P, Tremblay P, Prusiner SB, Cohen FE, Westaway D.
    J Biol Chem; 2000 Sep 01; 275(35):26834-41. PubMed ID: 10842180
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  • 10. Doppel-induced cerebellar degeneration in transgenic mice.
    Moore RC, Mastrangelo P, Bouzamondo E, Heinrich C, Legname G, Prusiner SB, Hood L, Westaway D, DeArmond SJ, Tremblay P.
    Proc Natl Acad Sci U S A; 2001 Dec 18; 98(26):15288-93. PubMed ID: 11734625
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  • 11. Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel.
    Moore RC, Lee IY, Silverman GL, Harrison PM, Strome R, Heinrich C, Karunaratne A, Pasternak SH, Chishti MA, Liang Y, Mastrangelo P, Wang K, Smit AF, Katamine S, Carlson GA, Cohen FE, Prusiner SB, Melton DW, Tremblay P, Hood LE, Westaway D.
    J Mol Biol; 1999 Oct 01; 292(4):797-817. PubMed ID: 10525406
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  • 12. The prion gene complex encoding PrP(C) and Doppel: insights from mutational analysis.
    Mastrangelo P, Westaway D.
    Gene; 2001 Sep 05; 275(1):1-18. PubMed ID: 11574147
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  • 15. Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: implications for doppel function.
    Wong BS, Liu T, Paisley D, Li R, Pan T, Chen SG, Perry G, Petersen RB, Smith MA, Melton DW, Gambetti P, Brown DR, Sy MS.
    Mol Cell Neurosci; 2001 Apr 05; 17(4):768-75. PubMed ID: 11312611
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  • 16. Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions.
    Genoud N, Behrens A, Miele G, Robay D, Heppner FL, Freigang S, Aguzzi A.
    Proc Natl Acad Sci U S A; 2004 Mar 23; 101(12):4198-203. PubMed ID: 15007175
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  • 18. Cell-autonomous PrP-Doppel interaction regulates apoptosis in PrP gene-deficient neuronal cells.
    Sakudo A, Lee DC, Nakamura I, Taniuchi Y, Saeki K, Matsumoto Y, Itohara S, Ikuta K, Onodera T.
    Biochem Biophys Res Commun; 2005 Jul 29; 333(2):448-54. PubMed ID: 15950943
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  • 20. Molecular biology of prion protein and its first homologous protein.
    Sakaguchi S.
    J Med Invest; 2007 Aug 29; 54(3-4):211-23. PubMed ID: 17878669
    [Abstract] [Full Text] [Related]

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