These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

166 related items for PubMed ID: 1501229

  • 1. Dispiro-1,2,4,5-tetraoxanes: a new class of antimalarial peroxides.
    Vennerstrom JL, Fu HN, Ellis WY, Ager AL, Wood JK, Andersen SL, Gerena L, Milhous WK.
    J Med Chem; 1992 Aug 07; 35(16):3023-7. PubMed ID: 1501229
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and antimalarial activity of sixteen dispiro-1,2,4, 5-tetraoxanes: alkyl-substituted 7,8,15,16-tetraoxadispiro[5.2.5. 2]hexadecanes.
    Vennerstrom JL, Dong Y, Andersen SL, Ager AL, Fu H, Miller RE, Wesche DL, Kyle DE, Gerena L, Walters SM, Wood JK, Edwards G, Holme AD, McLean WG, Milhous WK.
    J Med Chem; 2000 Jul 13; 43(14):2753-8. PubMed ID: 10893313
    [Abstract] [Full Text] [Related]

  • 3. Comparative antimalarial activities and ADME profiles of ozonides (1,2,4-trioxolanes) OZ277, OZ439, and their 1,2-dioxolane, 1,2,4-trioxane, and 1,2,4,5-tetraoxane isosteres.
    Wang X, Dong Y, Wittlin S, Charman SA, Chiu FC, Chollet J, Katneni K, Mannila J, Morizzi J, Ryan E, Scheurer C, Steuten J, Santo Tomas J, Snyder C, Vennerstrom JL.
    J Med Chem; 2013 Mar 28; 56(6):2547-55. PubMed ID: 23489135
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and antimalarial activity of 11 dispiro-1,2,4,5-tetraoxane analogues of WR 148999. 7,8,15,16-Tetraoxadispiro[5.2.5.2]hexadecanes substituted at the 1 and 10 positions with unsaturated and polar functional groups.
    Dong Y, Matile H, Chollet J, Kaminsky R, Wood JK, Vennerstrom JL.
    J Med Chem; 1999 Apr 22; 42(8):1477-80. PubMed ID: 10212135
    [Abstract] [Full Text] [Related]

  • 5. Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles.
    Ellis GL, Amewu R, Sabbani S, Stocks PA, Shone A, Stanford D, Gibbons P, Davies J, Vivas L, Charnaud S, Bongard E, Hall C, Rimmer K, Lozanom S, Jesús M, Gargallo D, Ward SA, O'Neill PM.
    J Med Chem; 2008 Apr 10; 51(7):2170-7. PubMed ID: 18341274
    [Abstract] [Full Text] [Related]

  • 6. Comparison of the reactivity of antimalarial 1,2,4,5-tetraoxanes with 1,2,4-trioxolanes in the presence of ferrous iron salts, heme, and ferrous iron salts/phosphatidylcholine.
    Bousejra-El Garah F, Wong MH, Amewu RK, Muangnoicharoen S, Maggs JL, Stigliani JL, Park BK, Chadwick J, Ward SA, O'Neill PM.
    J Med Chem; 2011 Oct 13; 54(19):6443-55. PubMed ID: 21888440
    [Abstract] [Full Text] [Related]

  • 7. Assessment of the antimalarial potential of tetraoxane WR 148999.
    Vennerstrom JL, Ager AL, Andersen SL, Grace JM, Wongpanich V, Angerhofer CK, Hu JK, Wesche DL.
    Am J Trop Med Hyg; 2000 May 13; 62(5):573-8. PubMed ID: 11289666
    [Abstract] [Full Text] [Related]

  • 8. Comparative antimalarial activities of six pairs of 1,2,4,5-tetraoxanes (peroxide dimers) and 1,2,4,5,7,8-hexaoxonanes (peroxide trimers).
    Dong Y, Creek D, Chollet J, Matile H, Charman SA, Wittlin S, Wood JK, Vennerstrom JL.
    Antimicrob Agents Chemother; 2007 Aug 13; 51(8):3033-5. PubMed ID: 17485500
    [Abstract] [Full Text] [Related]

  • 9. Spiro- and dispiro-1,2-dioxolanes: contribution of iron(II)-mediated one-electron vs two-electron reduction to the activity of antimalarial peroxides.
    Wang X, Dong Y, Wittlin S, Creek D, Chollet J, Charman SA, Tomas JS, Scheurer C, Snyder C, Vennerstrom JL.
    J Med Chem; 2007 Nov 15; 50(23):5840-7. PubMed ID: 17949067
    [Abstract] [Full Text] [Related]

  • 10. 1,2,4,5-Tetraoxane derivatives/hybrids as potent antimalarial endoperoxides: Chronological advancements, structure-activity relationship (SAR) studies and future perspectives.
    T A AR, Rajendra TN, Suhas KP, Ippagunta SK, Chaudhary S.
    Med Res Rev; 2024 Sep 15; 44(5):2266-2290. PubMed ID: 38618882
    [Abstract] [Full Text] [Related]

  • 11. Methyl-substituted dispiro-1,2,4,5-tetraoxanes: correlations of structural studies with antimalarial activity.
    McCullough KJ, Wood JK, Bhattacharjee AK, Dong Y, Kyle DE, Milhous WK, Vennerstrom JL.
    J Med Chem; 2000 Mar 23; 43(6):1246-9. PubMed ID: 10737758
    [Abstract] [Full Text] [Related]

  • 12. Antimalarial activity of endoperoxide compound 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol.
    Sato A, Hiramoto A, Morita M, Matsumoto M, Komich Y, Nakase Y, Tanigawa N, Hiraoka O, Hiramoto K, Hayatsu H, Higaki K, Kawai S, Masuyama A, Nojima M, Wataya Y, Kim HS.
    Parasitol Int; 2011 Sep 23; 60(3):270-3. PubMed ID: 21501696
    [Abstract] [Full Text] [Related]

  • 13. Tetraoxanes: synthetic and medicinal chemistry perspective.
    Kumar N, Singh R, Rawat DS.
    Med Res Rev; 2012 May 23; 32(3):581-610. PubMed ID: 22675731
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and antimalarial activity of dihydroperoxides and tetraoxanes conjugated with bis(benzyl)acetone derivatives.
    Franco LL, de Almeida MV, E Silva LF, Vieira PP, Pohlit AM, Valle MS.
    Chem Biol Drug Des; 2012 May 23; 79(5):790-7. PubMed ID: 22284812
    [Abstract] [Full Text] [Related]

  • 15. Steroidal geminal dihydroperoxides and 1,2,4,5-tetraoxanes: structure determination and their antimalarial activity.
    Todorović NM, Stefanović M, Tinant B, Declercq JP, Makler MT, Solaja BA.
    Steroids; 1996 Dec 23; 61(12):688-96. PubMed ID: 8987137
    [Abstract] [Full Text] [Related]

  • 16. Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane.
    Blank BR, Gut J, Rosenthal PJ, Renslo AR.
    J Med Chem; 2017 Jul 27; 60(14):6400-6407. PubMed ID: 28692297
    [Abstract] [Full Text] [Related]

  • 17. Plasmodium falciparum endoplasmic reticulum-resident calcium binding protein is a possible target of synthetic antimalarial endoperoxides, N-89 and N-251.
    Morita M, Sanai H, Hiramoto A, Sato A, Hiraoka O, Sakura T, Kaneko O, Masuyama A, Nojima M, Wataya Y, Kim HS.
    J Proteome Res; 2012 Dec 07; 11(12):5704-11. PubMed ID: 23061985
    [Abstract] [Full Text] [Related]

  • 18. The structure-activity relationship of the antimalarial ozonide arterolane (OZ277).
    Dong Y, Wittlin S, Sriraghavan K, Chollet J, Charman SA, Charman WN, Scheurer C, Urwyler H, Santo Tomas J, Snyder C, Creek DJ, Morizzi J, Koltun M, Matile H, Wang X, Padmanilayam M, Tang Y, Dorn A, Brun R, Vennerstrom JL.
    J Med Chem; 2010 Jan 14; 53(1):481-91. PubMed ID: 19924861
    [Abstract] [Full Text] [Related]

  • 19. Dispiro-1,2,4-trioxane analogues of a prototype dispiro-1,2,4-trioxolane: mechanistic comparators for artemisinin in the context of reaction pathways with iron(II).
    Tang Y, Dong Y, Wang X, Sriraghavan K, Wood JK, Vennerstrom JL.
    J Org Chem; 2005 Jun 24; 70(13):5103-10. PubMed ID: 15960511
    [Abstract] [Full Text] [Related]

  • 20. Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action.
    Chadwick J, Amewu RK, Marti F, Garah FB, Sharma R, Berry NG, Stocks PA, Burrell-Saward H, Wittlin S, Rottmann M, Brun R, Taramelli D, Parapini S, Ward SA, O'Neill PM.
    ChemMedChem; 2011 Aug 01; 6(8):1357-61. PubMed ID: 21692184
    [No Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 9.