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Journal Abstract Search

245 related items for PubMed ID: 15013001

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  • 2. Novel P1 chain-extended HIV protease inhibitors possessing potent anti-HIV activity and remarkable inverse antiviral resistance profiles.
    Miller JF, Brieger M, Furfine ES, Hazen RJ, Kaldor I, Reynolds D, Sherrill RG, Spaltenstein A.
    Bioorg Med Chem Lett; 2005 Aug 01; 15(15):3496-500. PubMed ID: 15990305
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  • 8. PL-100, a novel HIV-1 protease inhibitor displaying a high genetic barrier to resistance: an in vitro selection study.
    Dandache S, Coburn CA, Oliveira M, Allison TJ, Holloway MK, Wu JJ, Stranix BR, Panchal C, Wainberg MA, Vacca JP.
    J Med Virol; 2008 Dec 01; 80(12):2053-63. PubMed ID: 19040279
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  • 11. Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor.
    Surleraux DL, Tahri A, Verschueren WG, Pille GM, de Kock HA, Jonckers TH, Peeters A, De Meyer S, Azijn H, Pauwels R, de Bethune MP, King NM, Prabu-Jeyabalan M, Schiffer CA, Wigerinck PB.
    J Med Chem; 2005 Mar 24; 48(6):1813-22. PubMed ID: 15771427
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  • 13. Resistance to HIV protease inhibitors: a comparison of enzyme inhibition and antiviral potency.
    Klabe RM, Bacheler LT, Ala PJ, Erickson-Viitanen S, Meek JL.
    Biochemistry; 1998 Jun 16; 37(24):8735-42. PubMed ID: 9628735
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  • 14. Novel inhibitors of HIV protease: design, synthesis and biological evaluation of picomolar inhibitors containing cyclic P1/P2 scaffolds.
    Spaltenstein A, Almond MR, Bock WJ, Cleary DG, Furfine ES, Hazen RJ, Kazmierski WM, Salituro FG, Tung RD, Wright LL.
    Bioorg Med Chem Lett; 2000 Jun 05; 10(11):1159-62. PubMed ID: 10866371
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  • 15. Synthesis of novel HIV protease inhibitors (PI) with activity against PI-resistant virus.
    Raghavan S, Lu Z, Beeson T, Chapman KT, Schleif WA, Olsen DB, Stahlhut M, Rutkowski CA, Gabryelski L, Emini E, Tata JR.
    Bioorg Med Chem Lett; 2007 Oct 01; 17(19):5432-6. PubMed ID: 17692518
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  • 18. Synthesis and biological evaluation of novel amprenavir-based P1-substituted bi-aryl derivatives as ultra-potent HIV-1 protease inhibitors.
    Yan J, Huang N, Li S, Yang LM, Xing W, Zheng YT, Hu Y.
    Bioorg Med Chem Lett; 2012 Mar 01; 22(5):1976-9. PubMed ID: 22306123
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  • 20. Reduction of peptide character of HIV protease inhibitors that exhibit nanomolar potency against multidrug resistant HIV-1 strains.
    Tamamura H, Koh Y, Ueda S, Sasaki Y, Yamasaki T, Aoki M, Maeda K, Watai Y, Arikuni H, Otaka A, Mitsuya H, Fujii N.
    J Med Chem; 2003 Apr 24; 46(9):1764-8. PubMed ID: 12699395
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