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Journal Abstract Search

352 related items for PubMed ID: 15013815

  • 1. Enzymology of a carbonyl reduction clearance pathway for the HIV integrase inhibitor, S-1360: role of human liver cytosolic aldo-keto reductases.
    Rosemond MJ, St John-Williams L, Yamaguchi T, Fujishita T, Walsh JS.
    Chem Biol Interact; 2004 Mar 15; 147(2):129-39. PubMed ID: 15013815
    [Abstract] [Full Text] [Related]

  • 2. Purification and characterization of oxidoreductases-catalyzing carbonyl reduction of the tobacco-specific nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human liver cytosol.
    Atalla A, Breyer-Pfaff U, Maser E.
    Xenobiotica; 2000 Aug 15; 30(8):755-69. PubMed ID: 11037109
    [Abstract] [Full Text] [Related]

  • 3. Investigations on the metabolic stability of cytosolic phospholipase A2α inhibitors with 1-indolylpropan-2-one structure.
    Fabian J, Hanekamp W, Thomas MH, Olivier JL, Lehr M.
    Chem Biol Interact; 2013 Nov 25; 206(2):356-63. PubMed ID: 24120545
    [Abstract] [Full Text] [Related]

  • 4. Carbonyl reduction of bupropion in human liver.
    Molnari JC, Myers AL.
    Xenobiotica; 2012 Jun 25; 42(6):550-61. PubMed ID: 22339467
    [Abstract] [Full Text] [Related]

  • 5. Characterization of human liver enzymes involved in the biotransformation of boceprevir, a hepatitis C virus protease inhibitor.
    Ghosal A, Yuan Y, Tong W, Su AD, Gu C, Chowdhury SK, Kishnani NS, Alton KB.
    Drug Metab Dispos; 2011 Mar 25; 39(3):510-21. PubMed ID: 21123164
    [Abstract] [Full Text] [Related]

  • 6. Carbonyl reduction of warfarin: Identification and characterization of human warfarin reductases.
    Malátková P, Sokolová S, Chocholoušová Havlíková L, Wsól V.
    Biochem Pharmacol; 2016 Jun 01; 109():83-90. PubMed ID: 27055738
    [Abstract] [Full Text] [Related]

  • 7. In vitro metabolism and identification of human enzymes involved in the metabolism of methylnaltrexone.
    Tong Z, Chandrasekaran A, Li H, Rotshteyn Y, Erve JC, Demaio W, Talaat R, Hultin T, Scatina J.
    Drug Metab Dispos; 2010 May 01; 38(5):801-7. PubMed ID: 20173089
    [Abstract] [Full Text] [Related]

  • 8. Carbonyl reduction of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by cytosolic enzymes in human liver and lung.
    Maser E, Stinner B, Atalla A.
    Cancer Lett; 2000 Feb 01; 148(2):135-44. PubMed ID: 10695989
    [Abstract] [Full Text] [Related]

  • 9. Partial purification and characterization of a new human membrane-bound carbonyl reductase playing a role in the deactivation of the anticancer drug oracin.
    Skarydová L, Skarka A, Novotná R, Zivná L, Martin HJ, Wsól V, Maser E.
    Toxicology; 2009 Oct 01; 264(1-2):52-60. PubMed ID: 19635524
    [Abstract] [Full Text] [Related]

  • 10. Characterization of a unique aldo-keto reductase responsible for the reduction of chlordecone in the liver of the gerbil and man.
    Molowa DT, Wrighton SA, Blanke RV, Guzelian PS.
    J Toxicol Environ Health; 1986 Oct 01; 17(4):375-84. PubMed ID: 2420999
    [Abstract] [Full Text] [Related]

  • 11. Aldo-keto reductases in retinoid metabolism: search for substrate specificity and inhibitor selectivity.
    Porté S, Xavier Ruiz F, Giménez J, Molist I, Alvarez S, Domínguez M, Alvarez R, de Lera AR, Parés X, Farrés J.
    Chem Biol Interact; 2013 Feb 25; 202(1-3):186-94. PubMed ID: 23220004
    [Abstract] [Full Text] [Related]

  • 12. In vitro characterization of the enzymes involved in the metabolism of 1-furan-2-yl-3-pyridin-2-yl-propenone, an anti-inflammatory propenone compound.
    Lee SK, Kim JH, Seo YM, Kim HC, Kang MJ, Jeong HG, Lee ES, Jeong TC.
    Arch Pharm Res; 2008 Jun 25; 31(6):764-70. PubMed ID: 18563359
    [Abstract] [Full Text] [Related]

  • 13. Reductive metabolism of the sanguinarine iminium bond by rat liver preparations.
    Wu Y, Liu ZY, Cao Y, Chen XJ, Zeng JG, Sun ZL.
    Pharmacol Rep; 2013 Jun 25; 65(5):1391-400. PubMed ID: 24399736
    [Abstract] [Full Text] [Related]

  • 14. The role of carbonyl reducing enzymes in oxcarbazepine in vitro metabolism in man.
    Malátková P, Havlíková L, Wsól V.
    Chem Biol Interact; 2014 Sep 05; 220():241-7. PubMed ID: 25063510
    [Abstract] [Full Text] [Related]

  • 15. Chiral inversion of RS-8359: a selective and reversible MAO-A inhibitor via oxido-reduction of keto-alcohol.
    Itoh K, Hoshino K, Endo A, Asakawa T, Yamakami K, Noji C, Kosaka T, Tanaka Y.
    Chirality; 2006 Sep 05; 18(9):698-706. PubMed ID: 16823812
    [Abstract] [Full Text] [Related]

  • 16. Carbonyl reduction of naltrexone and dolasetron by oxidoreductases isolated from human liver cytosol.
    Breyer-Pfaff U, Nill K.
    J Pharm Pharmacol; 2004 Dec 05; 56(12):1601-6. PubMed ID: 15563768
    [Abstract] [Full Text] [Related]

  • 17. Effect of experimental kidney disease on the functional expression of hepatic reductases.
    Alshogran OY, Naud J, Ocque AJ, Leblond FA, Pichette V, Nolin TD.
    Drug Metab Dispos; 2015 Jan 05; 43(1):100-6. PubMed ID: 25332430
    [Abstract] [Full Text] [Related]

  • 18. Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride.
    Huskey SW, Dean DC, Miller RR, Rasmusson GH, Chiu SH.
    Drug Metab Dispos; 1995 Oct 05; 23(10):1126-35. PubMed ID: 8654202
    [Abstract] [Full Text] [Related]

  • 19. Neonicotinoid insecticides: reduction and cleavage of imidacloprid nitroimine substituent by liver microsomal and cytosolic enzymes.
    Schulz-Jander DA, Leimkuehler WM, Casida JE.
    Chem Res Toxicol; 2002 Sep 05; 15(9):1158-65. PubMed ID: 12230409
    [Abstract] [Full Text] [Related]

  • 20. High-affinity stereoselective reduction of the enantiomers of ketotifen and of ketonic nortriptyline metabolites by aldo-keto reductases from human liver.
    Breyer-Pfaff U, Nill K.
    Biochem Pharmacol; 2000 Feb 01; 59(3):249-60. PubMed ID: 10609553
    [Abstract] [Full Text] [Related]

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