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494 related items for PubMed ID: 15015586

  • 1. A P-glycoprotein- and MRP1-independent doxorubicin-resistant variant of the MCF-7 breast cancer cell line with defects in caspase-6, -7, -8, -9 and -10 activation pathways.
    Park SJ, Wu CH, Safa AR.
    Anticancer Res; 2004; 24(1):123-31. PubMed ID: 15015586
    [Abstract] [Full Text] [Related]

  • 2. Molecular mechanisms of loss of beta 2-microglobulin expression in drug-resistant breast cancer sublines and its involvement in drug resistance.
    Ogretmen B, McCauley MD, Safa AR.
    Biochemistry; 1998 Aug 18; 37(33):11679-91. PubMed ID: 9709006
    [Abstract] [Full Text] [Related]

  • 3. Proteinase-3, a serine protease which mediates doxorubicin-induced apoptosis in the HL-60 leukemia cell line, is downregulated in its doxorubicin-resistant variant.
    Wu CH, Gordon J, Rastegar M, Ogretmen B, Safa AR.
    Oncogene; 2002 Aug 01; 21(33):5160-74. PubMed ID: 12140766
    [Abstract] [Full Text] [Related]

  • 4. Reconstitution of caspase 3 sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis.
    Yang XH, Sladek TL, Liu X, Butler BR, Froelich CJ, Thor AD.
    Cancer Res; 2001 Jan 01; 61(1):348-54. PubMed ID: 11196185
    [Abstract] [Full Text] [Related]

  • 5. Drug-resistant breast carcinoma (MCF-7) cells are paradoxically sensitive to apoptosis.
    Chen JS, Konopleva M, Andreeff M, Multani AS, Pathak S, Mehta K.
    J Cell Physiol; 2004 Aug 01; 200(2):223-34. PubMed ID: 15174092
    [Abstract] [Full Text] [Related]

  • 6. [Mechanism of apoptosis induced by SIRT1 deacetylase inhibitors in human breast cancer MCF-7 drug-resistant cells].
    Li Y, Xu R, Zhang XM, Li DD, He QY.
    Yao Xue Xue Bao; 2008 Oct 01; 43(10):1003-10. PubMed ID: 19127863
    [Abstract] [Full Text] [Related]

  • 7. P-glycoprotein enhances TRAIL-triggered apoptosis in multidrug resistant cancer cells by interacting with the death receptor DR5.
    Park SJ, Wu CH, Choi MR, Najafi F, Emami A, Safa AR.
    Biochem Pharmacol; 2006 Jul 28; 72(3):293-307. PubMed ID: 16753135
    [Abstract] [Full Text] [Related]

  • 8. Induction of multidrug resistance in MOLT-4 cells by anticancer agents is closely related to increased expression of functional P-glycoprotein and MDR1 mRNA.
    Liu ZL, Onda K, Tanaka S, Toma T, Hirano T, Oka K.
    Cancer Chemother Pharmacol; 2002 May 28; 49(5):391-7. PubMed ID: 11976833
    [Abstract] [Full Text] [Related]

  • 9. REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer.
    Kawasaki K, Watanabe M, Sakaguchi M, Ogasawara Y, Ochiai K, Nasu Y, Doihara H, Kashiwakura Y, Huh NH, Kumon H, Date H.
    Cancer Gene Ther; 2009 Jan 28; 16(1):65-72. PubMed ID: 18654608
    [Abstract] [Full Text] [Related]

  • 10. Efficient induction of apoptosis by doxorubicin coupled to cell-penetrating peptides compared to unconjugated doxorubicin in the human breast cancer cell line MDA-MB 231.
    Aroui S, Brahim S, De Waard M, Bréard J, Kenani A.
    Cancer Lett; 2009 Nov 18; 285(1):28-38. PubMed ID: 19523755
    [Abstract] [Full Text] [Related]

  • 11. Ceramide reduction and transcriptional up-regulation of glucosylceramide synthase through doxorubicin-activated Sp1 in drug-resistant HL-60/ADR cells.
    Uchida Y, Itoh M, Taguchi Y, Yamaoka S, Umehara H, Ichikawa S, Hirabayashi Y, Holleran WM, Okazaki T.
    Cancer Res; 2004 Sep 01; 64(17):6271-9. PubMed ID: 15342415
    [Abstract] [Full Text] [Related]

  • 12. Reversal effect of isotetrandrine, an isoquinoline alkaloid extracted from Caulis Mahoniae, on P-glycoprotein-mediated doxorubicin-resistance in human breast cancer (MCF-7/DOX) cells.
    Wang TX, Yang XH.
    Yao Xue Xue Bao; 2008 May 01; 43(5):461-6. PubMed ID: 18717331
    [Abstract] [Full Text] [Related]

  • 13. Mechanism of apoptosis induced by doxorubicin through the generation of hydrogen peroxide.
    Mizutani H, Tada-Oikawa S, Hiraku Y, Kojima M, Kawanishi S.
    Life Sci; 2005 Feb 11; 76(13):1439-53. PubMed ID: 15680309
    [Abstract] [Full Text] [Related]

  • 14. Adenovirus-mediated p53 gene therapy reverses resistance of breast cancer cells to adriamycin.
    Qi X, Chang Z, Song J, Gao G, Shen Z.
    Anticancer Drugs; 2011 Jul 11; 22(6):556-62. PubMed ID: 21637162
    [Abstract] [Full Text] [Related]

  • 15. Zinc inhibition of caspase-3 activation does not protect HeLa cells from apoptotic cell death.
    Lambert JC, Wang GW, Kang YJ.
    Toxicol Appl Pharmacol; 2001 Aug 15; 175(1):89-93. PubMed ID: 11509031
    [Abstract] [Full Text] [Related]

  • 16. Comparative study of human breast carcinoma MCF-7 cells differing in their resistance to doxorubicin: effect of ionizing radiation on apoptosis and TGF-beta production.
    Chorna I, Bilyy R, Datsyuk L, Stoika R.
    Exp Oncol; 2004 Jun 15; 26(2):111-7. PubMed ID: 15273662
    [Abstract] [Full Text] [Related]

  • 17. Sigma-2 receptor agonists activate a novel apoptotic pathway and potentiate antineoplastic drugs in breast tumor cell lines.
    Crawford KW, Bowen WD.
    Cancer Res; 2002 Jan 01; 62(1):313-22. PubMed ID: 11782394
    [Abstract] [Full Text] [Related]

  • 18. Hyperthermia engages the intrinsic apoptotic pathway by enhancing upstream caspase activation to overcome apoptotic resistance in MCF-7 breast adenocarcinoma cells.
    Klostergaard J, Leroux ME, Auzenne E, Khodadadian M, Spohn W, Wu JY, Donato NJ.
    J Cell Biochem; 2006 May 15; 98(2):356-69. PubMed ID: 16440323
    [Abstract] [Full Text] [Related]

  • 19. Antioxidant and xenobiotic-metabolizing enzyme gene expression in doxorubicin-resistant MCF-7 breast cancer cells.
    Akman SA, Forrest G, Chu FF, Esworthy RS, Doroshow JH.
    Cancer Res; 1990 Mar 01; 50(5):1397-402. PubMed ID: 2406012
    [Abstract] [Full Text] [Related]

  • 20. 2-Methoxyestradiol and multidrug resistance: can 2-methoxyestradiol chemosensitize resistant breast cancer cells?
    Azab SS, Salama SA, Abdel-Naim AB, Khalifa AE, El-Demerdash E, Al-Hendy A.
    Breast Cancer Res Treat; 2009 Jan 01; 113(1):9-19. PubMed ID: 18228136
    [Abstract] [Full Text] [Related]

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