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145 related items for PubMed ID: 15018825

  • 1. The pyridinyl-6 position of WAY-100635 as a site for radiofluorination--effect on 5-HT1A receptor radioligand behavior in vivo.
    McCarron JA, Pike VW, Halldin C, Sandell J, Sóvágó J, Gulyas B, Cselényi Z, Wikström HV, Marchais-Oberwinkler S, Nowicki B, Dollé F, Farde L.
    Mol Imaging Biol; 2004; 6(1):17-26. PubMed ID: 15018825
    [Abstract] [Full Text] [Related]

  • 2. New halogenated [11C]WAY analogues, [11C]6FPWAY and [11C]6BPWAY--radiosynthesis and assessment as radioligands for the study of brain 5-HT1A receptors in living monkey.
    Sandell J, Halldin C, Pike VW, Chou YH, Varnäs K, Hall H, Marchais S, Nowicki B, Wikström HV, Swahn CG, Farde L.
    Nucl Med Biol; 2001 Feb; 28(2):177-85. PubMed ID: 11295428
    [Abstract] [Full Text] [Related]

  • 3. Characterisation of the appearance of radioactive metabolites in monkey and human plasma from the 5-HT1A receptor radioligand, [carbonyl-11C]WAY-100635--explanation of high signal contrast in PET and an aid to biomathematical modelling.
    Osman S, Lundkvist C, Pike VW, Halldin C, McCarron JA, Swahn CG, Farde L, Ginovart N, Luthra SK, Gunn RN, Bench CJ, Sargent PA, Grasby PM.
    Nucl Med Biol; 1998 Apr; 25(3):215-23. PubMed ID: 9620626
    [Abstract] [Full Text] [Related]

  • 4. N-oxide analogs of WAY-100635: new high affinity 5-HT(1A) receptor antagonists.
    Marchais-Oberwinkler S, Nowicki B, Pike VW, Halldin C, Sandell J, Chou YH, Gulyas B, Brennum LT, Farde L, Wikström HV.
    Bioorg Med Chem; 2005 Feb 01; 13(3):883-93. PubMed ID: 15653354
    [Abstract] [Full Text] [Related]

  • 5. [carbonyl-11C]Desmethyl-WAY-100635 (DWAY) is a potent and selective radioligand for central 5-HT1A receptors in vitro and in vivo.
    Pike VW, Halldin C, McCarron JA, Lundkvist C, Hirani E, Olsson H, Hume SP, Karlsson P, Osman S, Swahn CG, Hall H, Wikström H, Mensonidas M, Poole KG, Farde L.
    Eur J Nucl Med; 1998 Apr 01; 25(4):338-46. PubMed ID: 9553162
    [Abstract] [Full Text] [Related]

  • 6. Two C-methyl derivatives of [11C]WAY-100635--effects of an amido alpha-methyl group on metabolism and brain 5-HT1A receptor radioligand behavior in monkey.
    McCarron JA, Marchais-Oberwinkler S, Pike VW, Tarkiainen J, Halldin C, Sóvagó J, Gulyas B, Wikström HV, Farde L.
    Mol Imaging Biol; 2005 Apr 01; 7(3):209-19. PubMed ID: 15912425
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and initial evaluation of [11C](R)-RWAY in monkey-a new, simply labeled antagonist radioligand for imaging brain 5-HT1A receptors with PET.
    McCarron JA, Zoghbi SS, Shetty HU, Vermeulen ES, Wikström HV, Ichise M, Yasuno F, Halldin C, Innis RB, Pike VW.
    Eur J Nucl Med Mol Imaging; 2007 Oct 01; 34(10):1670-82. PubMed ID: 17579853
    [Abstract] [Full Text] [Related]

  • 8. Characterization of the radioactive metabolites of the 5-HT1A receptor radioligand, [O-methyl-11C]WAY-100635, in monkey and human plasma by HPLC: comparison of the behaviour of an identified radioactive metabolite with parent radioligand in monkey using PET.
    Osman S, Lundkvist C, Pike VW, Halldin C, McCarron JA, Swahn CG, Ginovart N, Luthra SK, Bench CJ, Grasby PM, Wikström H, Barf T, Cliffe IA, Fletcher A, Farde L.
    Nucl Med Biol; 1996 Jul 01; 23(5):627-34. PubMed ID: 8905828
    [Abstract] [Full Text] [Related]

  • 9. In vivo characterization of p-[(18)F]MPPF, a fluoro analog of WAY-100635 for visualization of 5-HT(1a) receptors.
    Ginovart N, Hassoun W, Le Bars D, Weissmann D, Leviel V.
    Synapse; 2000 Mar 01; 35(3):192-200. PubMed ID: 10657026
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biologic evaluation of a novel serotonin 5-HT1A receptor radioligand, 18F-labeled mefway, in rodents and imaging by PET in a nonhuman primate.
    Saigal N, Pichika R, Easwaramoorthy B, Collins D, Christian BT, Shi B, Narayanan TK, Potkin SG, Mukherjee J.
    J Nucl Med; 2006 Oct 01; 47(10):1697-706. PubMed ID: 17015907
    [Abstract] [Full Text] [Related]

  • 11. Tissue distribution, autoradiography, and metabolism of 4-(2'-methoxyphenyl)-1-[2' -[N-2"-pyridinyl)-p-[(18)F]fluorobenzamido]ethyl]piperazine (p-[(18)F]MPPF), a new serotonin 5-HT(1A) antagonist for positron emission tomography: An In vivo study in rats.
    Plenevaux A, Weissmann D, Aerts J, Lemaire C, Brihaye C, Degueldre C, Le Bars D, Comar D, Pujol J, Luxen A.
    J Neurochem; 2000 Aug 01; 75(2):803-11. PubMed ID: 10899958
    [Abstract] [Full Text] [Related]

  • 12. Synthesis of a [6-pyridinyl-18F]-labelled fluoro derivative of WAY-100635 as a candidate radioligand for brain 5-HT1A receptor imaging with PET.
    Karramkam M, Hinnen F, Berrehouma M, Hlavacek C, Vaufrey F, Halldin C, McCarron JA, Pike VW, Dollé F.
    Bioorg Med Chem; 2003 Jul 03; 11(13):2769-82. PubMed ID: 12788351
    [Abstract] [Full Text] [Related]

  • 13. The PET radioligand [carbonyl-(11)C]desmethyl-WAY-100635 binds to 5-HT(1A) receptors and provides a higher radioactive signal than [carbonyl-(11)C]WAY-100635 in the human brain.
    Andrée B, Halldin C, Pike VW, Gunn RN, Olsson H, Farde L.
    J Nucl Med; 2002 Mar 03; 43(3):292-303. PubMed ID: 11884487
    [Abstract] [Full Text] [Related]

  • 14. N-(4-[(18)F]-fluoropyridin-2-yl)-N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}carboxamides as analogs of WAY100635. New PET tracers of serotonin 5-HT(1A) receptors.
    García G, Abet V, Alajarín R, Álvarez-Builla J, Delgado M, García-García L, Bascuñana-Almarcha P, Peña-Salcedo C, Kelly J, Pozo MA.
    Eur J Med Chem; 2014 Oct 06; 85():795-806. PubMed ID: 25171752
    [Abstract] [Full Text] [Related]

  • 15.
    Cheng KT.
    ; 2004 Oct 06. PubMed ID: 20641616
    [Abstract] [Full Text] [Related]

  • 16. Quantification of serotonin 5-HT1A receptors in monkey brain with [11C](R)-(-)-RWAY.
    Yasuno F, Zoghbi SS, McCarron JA, Hong J, Ichise M, Brown AK, Gladding RL, Bacher JD, Pike VW, Innis RB.
    Synapse; 2006 Dec 01; 60(7):510-20. PubMed ID: 16952161
    [Abstract] [Full Text] [Related]

  • 17. PET-examination and metabolite evaluation in monkey of [(11)C]NAD-299, a radioligand for visualisation of the 5-HT(1A) receptor.
    Sandell J, Halldin C, Chou YH, Swahn CG, Thorberg SO, Farde L.
    Nucl Med Biol; 2002 Jan 01; 29(1):39-45. PubMed ID: 11786274
    [Abstract] [Full Text] [Related]

  • 18. PET imaging of brain 5-HT1A receptors in rat in vivo with 18F-FCWAY and improvement by successful inhibition of radioligand defluorination with miconazole.
    Tipre DN, Zoghbi SS, Liow JS, Green MV, Seidel J, Ichise M, Innis RB, Pike VW.
    J Nucl Med; 2006 Feb 01; 47(2):345-53. PubMed ID: 16455642
    [Abstract] [Full Text] [Related]

  • 19. In vivo binding of [123I]4-(2'-methoxyphenyl)-1-[2'-(N-2"-pyridinyl)- p-iodobenzamido-]ethyl-piperazine, p-MPPI, to 5-HT1A receptors in rat brain.
    Kung MP, Zhuang ZP, Frederick D, Kung HF.
    Synapse; 1994 Dec 01; 18(4):359-66. PubMed ID: 7886629
    [Abstract] [Full Text] [Related]

  • 20. Development of 5-HT1A receptor radioligands to determine receptor density and changes in endogenous 5-HT.
    Jagoda EM, Lang L, Tokugawa J, Simmons A, Ma Y, Contoreggi C, Kiesewetter D, Eckelman WC.
    Synapse; 2006 May 01; 59(6):330-41. PubMed ID: 16440292
    [Abstract] [Full Text] [Related]

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