These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

148 related items for PubMed ID: 15027851

  • 1. Design and synthesis of a fluoroindolocarbazole series as selective topoisomerase I active agents. Discovery of water-soluble 3,9-difluoro-12,13-dihydro-13-[6-amino-beta-D-glucopyranosyl]-5H,13H-benzo[b]- thienyl[2,3-a]pyrrolo[3,4-c]carbazole- 5,7(6H)-dione (BMS-251873) with curative antitumor activity against prostate carcinoma xenograft tumor model.
    Balasubramanian BN, St Laurent DR, Saulnier MG, Long BH, Bachand C, Beaulieu F, Clarke W, Deshpande M, Eummer J, Fairchild CR, Frennesson DB, Kramer R, Lee FY, Mahler M, Martel A, Naidu BN, Rose WC, Russell J, Ruediger E, Solomon C, Stoffan KM, Wong H, Wright JJ, Zimmermann K, Vyas DM.
    J Med Chem; 2004 Mar 25; 47(7):1609-12. PubMed ID: 15027851
    [Abstract] [Full Text] [Related]

  • 2. Novel antitumor indolocarbazole compound 6-N-formylamino-12,13-dihydro-1,11- dihydroxy-13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo[3,4- c]carbazole-5,7(6H)-dione (NB-506): induction of topoisomerase I-mediated DNA cleavage and mechanisms of cell line-selective cytotoxicity.
    Yoshinari T, Matsumoto M, Arakawa H, Okada H, Noguchi K, Suda H, Okura A, Nishimura S.
    Cancer Res; 1995 Mar 15; 55(6):1310-5. PubMed ID: 7882328
    [Abstract] [Full Text] [Related]

  • 3. Discovery of a fluoroindolo[2,3-a]carbazole clinical candidate with broad spectrum antitumor activity in preclinical tumor models superior to the marketed oncology drug, CPT-11.
    Saulnier MG, Balasubramanian BN, Long BH, Frennesson DB, Ruediger E, Zimmermann K, Eummer JT, St Laurent DR, Stoffan KM, Naidu BN, Mahler M, Beaulieu F, Bachand C, Lee FY, Fairchild CR, Stadnick LK, Rose WC, Solomon C, Wong H, Martel A, Wright JJ, Kramer R, Langley DR, Vyas DM.
    J Med Chem; 2005 Apr 07; 48(7):2258-61. PubMed ID: 15801816
    [Abstract] [Full Text] [Related]

  • 4.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 5.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 6. Design, synthesis and biological evaluation of substituted 11H-benzo[a]carbazole-5-carboxamides as novel antitumor agents.
    Wang YQ, Li XH, He Q, Chen Y, Xie YY, Ding J, Miao ZH, Yang CH.
    Eur J Med Chem; 2011 Dec 07; 46(12):5878-84. PubMed ID: 22000922
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, antitumour activity and structure-activity relationships of 5H-benzo[b]carbazoles.
    Asche C, Frank W, Albert A, Kucklaender U.
    Bioorg Med Chem; 2005 Feb 01; 13(3):819-37. PubMed ID: 15653349
    [Abstract] [Full Text] [Related]

  • 8. Synthesis of 5,6-dimethyl-9-methoxy-1-phenyl-6H-pyrido[4,3-b]carbazole derivatives and their cytotoxic activity.
    Jasztold-Howorko R, Pelczynska M, Nasulewicz A, Wietrzyk J, Opolski A.
    Arch Pharm (Weinheim); 2005 Nov 01; 338(11):556-61. PubMed ID: 16281305
    [Abstract] [Full Text] [Related]

  • 9. 9-substituted 6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazoles as highly selective and potent anaplastic lymphoma kinase inhibitors.
    Kinoshita K, Kobayashi T, Asoh K, Furuichi N, Ito T, Kawada H, Hara S, Ohwada J, Hattori K, Miyagi T, Hong WS, Park MJ, Takanashi K, Tsukaguchi T, Sakamoto H, Tsukuda T, Oikawa N.
    J Med Chem; 2011 Sep 22; 54(18):6286-94. PubMed ID: 21823617
    [Abstract] [Full Text] [Related]

  • 10. Synthesis of new camptothecin analogs with improved antitumor activities.
    Niizuma S, Tsukazaki M, Suda H, Murata T, Ohwada J, Ozawa S, Fukuda H, Murasaki C, Kohchi M, Morikami K, Yoshinari K, Endo M, Ura M, Tanimura H, Miyazaki Y, Takasuka T, Kawashima A, Nanba E, Nakano K, Ogawa K, Kobayashi K, Okabe H, Umeda I, Shimma N.
    Bioorg Med Chem Lett; 2009 Apr 01; 19(7):2018-21. PubMed ID: 19254843
    [Abstract] [Full Text] [Related]

  • 11. Indolocarbazole glycosides in inactive conformations.
    Facompré M, Carrasco C, Vezin H, Chisholm JD, Yoburn JC, Van Vranken DL, Bailly C.
    Chembiochem; 2003 May 09; 4(5):386-95. PubMed ID: 12740810
    [Abstract] [Full Text] [Related]

  • 12. Syntheses and biological evaluation of topoisomerase I-targeting agents related to 11-[2-(N,N-dimethylamino)ethyl]-2,3-dimethoxy-8,9-methylenedioxy-11H-isoquino[4,3-c]cinnolin-12-one (ARC-31).
    Satyanarayana M, Feng W, Cheng L, Liu AA, Tsai YC, Liu LF, LaVoie EJ.
    Bioorg Med Chem; 2008 Aug 15; 16(16):7824-31. PubMed ID: 18676151
    [Abstract] [Full Text] [Related]

  • 13.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 14.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 15. Photochemical electrocyclisation of 3-vinylindoles to pyrido[2,3-a]-, pyrido[4,3-a]- and thieno[2,3-a]-carbazoles: design, synthesis, DNA binding and antitumor cell cytotoxicity.
    Lemster T, Pindur U, Lenglet G, Depauw S, Dassi C, David-Cordonnier MH.
    Eur J Med Chem; 2009 Aug 15; 44(8):3235-52. PubMed ID: 19386396
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and anticancer activity of new 1-substituted-6H-pyrido[4,3-b]carbazole derivatives.
    Tylińska B, Jasztold-Howorko R, Mastalarz H, Szczaurska-Nowak K, Wietrzyk J.
    Arch Pharm (Weinheim); 2008 Jun 15; 341(6):351-6. PubMed ID: 18404778
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and evaluation of 4-amino-substituted 7-methoxy (and 7-hydroxy)- 11-methyl (and 5,11-dimethyl)-10H-pyrido [2,3-b] carbazoles and 4-amino- substituted 11-methyl (and 5,11-dimethyl)-10H-pyrido[3',4':4,5] pyrrolo [3,2-g] quinolines, two new series related to antitumor ellipticine derivatives.
    Moron J, Rautureau M, Huel C, Pierré A, Berthier LK, Atassi G, Bisagni E.
    Anticancer Drug Des; 1993 Dec 15; 8(6):399-416. PubMed ID: 8286009
    [Abstract] [Full Text] [Related]

  • 18. Novel antitumor L-arabinose derivative of indolocarbazole with high affinity to DNA.
    Kaluzhny DN, Tatarskiy VV, Dezhenkova LG, Plikhtyak IL, Miniker TD, Shchyolkina AK, Strel'tsov SA, Chilov GG, Novikov FN, Kubasova IY, Smirnova ZS, Mel'nik SY, Livshits MA, Borisova OF, Shtil AA.
    ChemMedChem; 2009 Oct 15; 4(10):1641-8. PubMed ID: 19672918
    [Abstract] [Full Text] [Related]

  • 19. Structure-activity relationships of indole compounds derived from combretastatin A4: synthesis and biological screening of 5-phenylpyrrolo[3,4-a]carbazole-1,3-diones as potential antivascular agents.
    Ty N, Dupeyre G, Chabot GG, Seguin J, Quentin L, Chiaroni A, Tillequin F, Scherman D, Michel S, Cachet X.
    Eur J Med Chem; 2010 Sep 15; 45(9):3726-39. PubMed ID: 20538383
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological activities of topoisomerase I inhibitors, 6-N-amino analogues of NB-506.
    Ohkubo M, Kojiri K, Kondo H, Tanaka S, Kawamoto H, Nishimura T, Nishimura I, Yoshinari T, Arakawa H, Suda H, Morishima H, Nishimura S.
    Bioorg Med Chem Lett; 1999 May 03; 9(9):1219-24. PubMed ID: 10340602
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 8.