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460 related items for PubMed ID: 15041478

  • 1. Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells.
    van Zanden JJ, Geraets L, Wortelboer HM, van Bladeren PJ, Rietjens IM, Cnubben NH.
    Biochem Pharmacol; 2004 Apr 15; 67(8):1607-17. PubMed ID: 15041478
    [Abstract] [Full Text] [Related]

  • 2. Detoxification of 1-chloro-2,4-dinitrobenzene in MCF7 breast cancer cells expressing glutathione S-transferase P1-1 and/or multidrug resistance protein 1.
    Diah SK, Smitherman PK, Townsend AJ, Morrow CS.
    Toxicol Appl Pharmacol; 1999 Jun 01; 157(2):85-93. PubMed ID: 10366541
    [Abstract] [Full Text] [Related]

  • 3. Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2.
    van Zanden JJ, Wortelboer HM, Bijlsma S, Punt A, Usta M, Bladeren PJ, Rietjens IM, Cnubben NH.
    Biochem Pharmacol; 2005 Feb 15; 69(4):699-708. PubMed ID: 15670588
    [Abstract] [Full Text] [Related]

  • 4. Reversal of in vitro cellular MRP1 and MRP2 mediated vincristine resistance by the flavonoid myricetin.
    van Zanden JJ, de Mul A, Wortelboer HM, Usta M, van Bladeren PJ, Rietjens IM, Cnubben NH.
    Biochem Pharmacol; 2005 Jun 01; 69(11):1657-65. PubMed ID: 15896345
    [Abstract] [Full Text] [Related]

  • 5. Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and derivatives through GSH efflux.
    Lorendeau D, Dury L, Genoux-Bastide E, Lecerf-Schmidt F, Simões-Pires C, Carrupt PA, Terreux R, Magnard S, Di Pietro A, Boumendjel A, Baubichon-Cortay H.
    Biochem Pharmacol; 2014 Aug 01; 90(3):235-45. PubMed ID: 24875445
    [Abstract] [Full Text] [Related]

  • 6. Modulation of human multidrug resistance protein (MRP) 1 (ABCC1) and MRP2 (ABCC2) transport activities by endogenous and exogenous glutathione-conjugated catechol metabolites.
    Slot AJ, Wise DD, Deeley RG, Monks TJ, Cole SP.
    Drug Metab Dispos; 2008 Mar 01; 36(3):552-60. PubMed ID: 18079363
    [Abstract] [Full Text] [Related]

  • 7. Interplay between MRP inhibition and metabolism of MRP inhibitors: the case of curcumin.
    Wortelboer HM, Usta M, van der Velde AE, Boersma MG, Spenkelink B, van Zanden JJ, Rietjens IM, van Bladeren PJ, Cnubben NH.
    Chem Res Toxicol; 2003 Dec 01; 16(12):1642-51. PubMed ID: 14680379
    [Abstract] [Full Text] [Related]

  • 8. Doxorubicin- and daunorubicin-glutathione conjugates, but not unconjugated drugs, competitively inhibit leukotriene C4 transport mediated by MRP/GS-X pump.
    Priebe W, Krawczyk M, Kuo MT, Yamane Y, Savaraj N, Ishikawa T.
    Biochem Biophys Res Commun; 1998 Jun 29; 247(3):859-63. PubMed ID: 9647783
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of multidrug resistance proteins MRP1 and MRP2 by a series of alpha,beta-unsaturated carbonyl compounds.
    Wortelboer HM, Usta M, van Zanden JJ, van Bladeren PJ, Rietjens IM, Cnubben NH.
    Biochem Pharmacol; 2005 Jun 15; 69(12):1879-90. PubMed ID: 15885658
    [Abstract] [Full Text] [Related]

  • 10. Formation and efflux of ATP-binding cassette transporter substrate 2,4-dinitrophenyl-S-glutathione from cultured human term placental villous tissue fragments.
    Vaidya SS, Walsh SW, Gerk PM.
    Mol Pharm; 2009 Jun 15; 6(6):1689-702. PubMed ID: 19397308
    [Abstract] [Full Text] [Related]

  • 11. Dynamics of glutathione conjugation and conjugate efflux in detoxification of the carcinogen, 4-nitroquinoline 1-oxide: contributions of glutathione, glutathione S-transferase, and MRP1.
    Peklak-Scott C, Townsend AJ, Morrow CS.
    Biochemistry; 2005 Mar 22; 44(11):4426-33. PubMed ID: 15766272
    [Abstract] [Full Text] [Related]

  • 12. Arsenic transport by the human multidrug resistance protein 1 (MRP1/ABCC1). Evidence that a tri-glutathione conjugate is required.
    Leslie EM, Haimeur A, Waalkes MP.
    J Biol Chem; 2004 Jul 30; 279(31):32700-8. PubMed ID: 15161912
    [Abstract] [Full Text] [Related]

  • 13. Role of multidrug-resistance protein 2 in glutathione S-transferase P1-1-mediated resistance to 4-nitroquinoline 1-oxide toxicities in HepG2 cells.
    Morrow CS, Smitherman PK, Townsend AJ.
    Mol Carcinog; 2000 Nov 30; 29(3):170-8. PubMed ID: 11108662
    [Abstract] [Full Text] [Related]

  • 14. Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells.
    Paumi CM, Wright M, Townsend AJ, Morrow CS.
    Biochemistry; 2003 May 13; 42(18):5429-37. PubMed ID: 12731885
    [Abstract] [Full Text] [Related]

  • 15. The effect of quercetin phase II metabolism on its MRP1 and MRP2 inhibiting potential.
    van Zanden JJ, van der Woude H, Vaessen J, Usta M, Wortelboer HM, Cnubben NH, Rietjens IM.
    Biochem Pharmacol; 2007 Jul 15; 74(2):345-51. PubMed ID: 17509533
    [Abstract] [Full Text] [Related]

  • 16. Role of multidrug resistance protein 2 (MRP2, ABCC2) in alkylating agent detoxification: MRP2 potentiates glutathione S-transferase A1-1-mediated resistance to chlorambucil cytotoxicity.
    Smitherman PK, Townsend AJ, Kute TE, Morrow CS.
    J Pharmacol Exp Ther; 2004 Jan 15; 308(1):260-7. PubMed ID: 14569069
    [Abstract] [Full Text] [Related]

  • 17. Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids.
    Leslie EM, Mao Q, Oleschuk CJ, Deeley RG, Cole SP.
    Mol Pharmacol; 2001 May 15; 59(5):1171-80. PubMed ID: 11306701
    [Abstract] [Full Text] [Related]

  • 18. Expression of MRP1 and GSTP1-1 modulate the acute cellular response to treatment with the chemopreventive isothiocyanate, sulforaphane.
    Sibhatu MB, Smitherman PK, Townsend AJ, Morrow CS.
    Carcinogenesis; 2008 Apr 15; 29(4):807-15. PubMed ID: 18204073
    [Abstract] [Full Text] [Related]

  • 19. Role of glutathione S-transferase P1-1 in the cellular detoxification of cisplatin.
    Peklak-Scott C, Smitherman PK, Townsend AJ, Morrow CS.
    Mol Cancer Ther; 2008 Oct 15; 7(10):3247-55. PubMed ID: 18852128
    [Abstract] [Full Text] [Related]

  • 20. Resistance to mitoxantrone in multidrug-resistant MCF7 breast cancer cells: evaluation of mitoxantrone transport and the role of multidrug resistance protein family proteins.
    Diah SK, Smitherman PK, Aldridge J, Volk EL, Schneider E, Townsend AJ, Morrow CS.
    Cancer Res; 2001 Jul 15; 61(14):5461-7. PubMed ID: 11454692
    [Abstract] [Full Text] [Related]

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