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Journal Abstract Search

198 related items for PubMed ID: 15044036

  • 1. Mutagenesis at the human tachykinin NK(2) receptor to define the binding site of a novel class of antagonists.
    Meini S, Bellucci F, Catalani C, Cucchi P, Patacchini R, Rotondaro L, Altamura M, Giuliani S, Giolitti A, Maggi CA.
    Eur J Pharmacol; 2004 Mar 19; 488(1-3):61-9. PubMed ID: 15044036
    [Abstract] [Full Text] [Related]

  • 2. Multifaceted approach to determine the antagonist molecular mechanism and interaction of ibodutant ([1-(2-phenyl-1R-[[1-(tetrahydropyran-4-ylmethyl)-piperidin-4-ylmethyl]-carbamoyl]-ethylcarbamoyl)-cyclopentyl]-amide) at the human tachykinin NK2 receptor.
    Meini S, Bellucci F, Catalani C, Cucchi P, Giolitti A, Santicioli P, Giuliani S.
    J Pharmacol Exp Ther; 2009 May 19; 329(2):486-95. PubMed ID: 19218528
    [Abstract] [Full Text] [Related]

  • 3. Relevance of aromatic residues in transmembrane segments V to VII for binding of peptide and nonpeptide antagonists to the human tachykinin NK(2) receptor.
    Renzetti AR, Catalioto RM, Criscuoli M, Cucchi P, Ferrer C, Giolitti A, Guelfi M, Rotondaro L, Warner FJ, Maggi CA.
    J Pharmacol Exp Ther; 1999 Aug 19; 290(2):487-95. PubMed ID: 10411554
    [Abstract] [Full Text] [Related]

  • 4. Pharmacology of an original and selective nonpeptide antagonist ligand for the human tachykinin NK2 receptor.
    Meini S, Catalani C, Bellucci F, Cucchi P, Giuliani S, Zappitelli S, Rotondaro L, Pasqui F, Guidi A, Altamura M, Giolitti A, Maggi CA.
    Eur J Pharmacol; 2005 Jun 01; 516(2):104-11. PubMed ID: 15925360
    [Abstract] [Full Text] [Related]

  • 5. MEN 11420 (Nepadutant), a novel glycosylated bicyclic peptide tachykinin NK2 receptor antagonist.
    Catalioto RM, Criscuoli M, Cucchi P, Giachetti A, Gianotti D, Giuliani S, Lecci A, Lippi A, Patacchini R, Quartara L, Renzetti AR, Tramontana M, Arcamone F, Maggi CA.
    Br J Pharmacol; 1998 Jan 01; 123(1):81-91. PubMed ID: 9484857
    [Abstract] [Full Text] [Related]

  • 6. MEN 10,627, a novel polycyclic peptide antagonist of tachykinin NK2 receptors.
    Maggi CA, Astolfi M, Giuliani S, Goso C, Manzini S, Meini S, Patacchini R, Pavone V, Pedone C, Quartara L.
    J Pharmacol Exp Ther; 1994 Dec 01; 271(3):1489-500. PubMed ID: 7996462
    [Abstract] [Full Text] [Related]

  • 7. Pharmacological evaluation of alpha and beta human tachykinin NK(2) receptor splice variants expressed in CHO cells.
    Bellucci F, Meini S, Catalioto RM, Catalani C, Giuliani S, Quartara L, Giolitti A, Faiella A, Rotondaro L, Candenas ML, Pinto FM, Maggi CA.
    Eur J Pharmacol; 2004 Sep 24; 499(3):229-38. PubMed ID: 15381044
    [Abstract] [Full Text] [Related]

  • 8. [3H][beta-Ala8]neurokinin A-(4-10): a novel, selective radioligand for the tachykinin NK2 receptor.
    Goso C, Astolfi M, Parlani M, Manzini S.
    Eur J Pharmacol; 1995 Dec 27; 294(1):239-45. PubMed ID: 8788437
    [Abstract] [Full Text] [Related]

  • 9. Effect of nepadutant at tachykinin NK(2) receptors in human intestine and urinary bladder.
    Patacchini R, Giuliani S, Turini A, Navarra G, Maggi CA.
    Eur J Pharmacol; 2000 Jun 23; 398(3):389-97. PubMed ID: 10862829
    [Abstract] [Full Text] [Related]

  • 10. MEN15596, a novel nonpeptide tachykinin NK2 receptor antagonist.
    Cialdai C, Tramontana M, Patacchini R, Lecci A, Catalani C, Catalioto RM, Meini S, Valenti C, Altamura M, Giuliani S, Maggi CA.
    Eur J Pharmacol; 2006 Nov 07; 549(1-3):140-8. PubMed ID: 16979621
    [Abstract] [Full Text] [Related]

  • 11. Monocyclic human tachykinin NK-2 receptor antagonists as evolution of a potent bicyclic antagonist: QSAR and site-directed mutagenesis studies.
    Giolitti A, Altamura M, Bellucci F, Giannotti D, Meini S, Patacchini R, Rotondaro L, Zappitelli S, Maggi CA.
    J Med Chem; 2002 Aug 01; 45(16):3418-29. PubMed ID: 12139452
    [Abstract] [Full Text] [Related]

  • 12. SCH 206272: a potent, orally active tachykinin NK(1), NK(2), and NK(3) receptor antagonist.
    Anthes JC, Chapman RW, Richard C, Eckel S, Corboz M, Hey JA, Fernandez X, Greenfeder S, McLeod R, Sehring S, Rizzo C, Crawley Y, Shih NY, Piwinski J, Reichard G, Ting P, Carruthers N, Cuss FM, Billah M, Kreutner W, Egan RW.
    Eur J Pharmacol; 2002 Aug 23; 450(2):191-202. PubMed ID: 12206858
    [Abstract] [Full Text] [Related]

  • 13. Effect of a tachykinin NK(2) receptor antagonist, nepadutant, on cardiovascular and gastrointestinal function in rats and dogs.
    Giuliani S, Guelfi M, Toulouse M, Buéno L, Lecci A, Tramontana M, Criscuoli M, Maggi CA.
    Eur J Pharmacol; 2001 Mar 09; 415(1):61-71. PubMed ID: 11245853
    [Abstract] [Full Text] [Related]

  • 14. Characterization of the antibronchoconstrictor activity of MEN 11420, a tachykinin NK2 receptor antagonist, in guinea-pigs.
    Tramontana M, Patacchini R, Giuliani S, Lippi A, Lecci A, Santicioli P, Criscuoli M, Maggi CA.
    Eur J Pharmacol; 1998 Jul 10; 352(2-3):279-88. PubMed ID: 9716365
    [Abstract] [Full Text] [Related]

  • 15. Molecular determinants of peptide and nonpeptide NK-2 receptor antagonists binding sites of the human tachykinin NK-2 receptor by site-directed mutagenesis.
    Giolitti A, Cucchi P, Renzetti AR, Rotondaro L, Zappitelli S, Maggi CA.
    Neuropharmacology; 2000 Jun 08; 39(8):1422-9. PubMed ID: 10818258
    [Abstract] [Full Text] [Related]

  • 16. Different mechanism of tachykinin NK2 receptor blockade by SR 48968 and MEN 10,627 in the guinea-pig isolated gallbladder and colon.
    Patacchini R, De Giorgio R, Giachetti A, Maggi CA.
    Eur J Pharmacol; 1994 Dec 12; 271(1):111-9. PubMed ID: 7698194
    [Abstract] [Full Text] [Related]

  • 17. Novel ligands lacking a positive charge for the delta- and mu-opioid receptors.
    Schiller PW, Berezowska I, Nguyen TM, Schmidt R, Lemieux C, Chung NN, Falcone-Hindley ML, Yao W, Liu J, Iwama S, Smith AB, Hirschmann R.
    J Med Chem; 2000 Feb 24; 43(4):551-9. PubMed ID: 10691681
    [Abstract] [Full Text] [Related]

  • 18. Tachykinin NK(2) receptor mediates contraction and ion transport in rat colon by different mechanisms.
    Patacchini R, Cox HM, Ståhl S, Tough IR, Maggi CA.
    Eur J Pharmacol; 2001 Mar 24; 415(2-3):277-83. PubMed ID: 11275010
    [Abstract] [Full Text] [Related]

  • 19. Pharmacological profile of the novel mammalian tachykinin, hemokinin 1.
    Bellucci F, Carini F, Catalani C, Cucchi P, Lecci A, Meini S, Patacchini R, Quartara L, Ricci R, Tramontana M, Giuliani S, Maggi CA.
    Br J Pharmacol; 2002 Jan 24; 135(1):266-74. PubMed ID: 11786503
    [Abstract] [Full Text] [Related]

  • 20. Effect of YM-44781, YM-44778 and YM-49598, novel tachykinin antagonists, in a drug-induced bladder contraction model.
    Choppin A, Groke G, Bringas A, Stepan G, Dillon MP.
    Pharmacology; 2002 May 24; 65(2):96-102. PubMed ID: 11937780
    [Abstract] [Full Text] [Related]

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