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167 related items for PubMed ID: 15045689

  • 1. Attenuation of hyperinsulinemia by NN414, a SUR1/Kir6.2 selective K-adenosine triphosphate channel opener, improves glucose tolerance and lipid profile in obese Zucker rats.
    Alemzadeh R, Fledelius C, Bodvarsdottir T, Sturis J.
    Metabolism; 2004 Apr; 53(4):441-7. PubMed ID: 15045689
    [Abstract] [Full Text] [Related]

  • 2. NN414, a SUR1/Kir6.2-selective potassium channel opener, reduces blood glucose and improves glucose tolerance in the VDF Zucker rat.
    Carr RD, Brand CL, Bodvarsdottir TB, Hansen JB, Sturis J.
    Diabetes; 2003 Oct; 52(10):2513-8. PubMed ID: 14514634
    [Abstract] [Full Text] [Related]

  • 3. Modulation of adipoinsular axis in prediabetic zucker diabetic fatty rats by diazoxide.
    Alemzadeh R, Tushaus KM.
    Endocrinology; 2004 Dec; 145(12):5476-84. PubMed ID: 15319354
    [Abstract] [Full Text] [Related]

  • 4. Chronic suppression of insulin by diazoxide alters the activities of key enzymes regulating hepatic gluconeogenesis in Zucker rats.
    Alemzadeh R, Holshouser S, Massey P, Koontz J.
    Eur J Endocrinol; 2002 Jun; 146(6):871-9. PubMed ID: 12039709
    [Abstract] [Full Text] [Related]

  • 5. Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets.
    Maedler K, Størling J, Sturis J, Zuellig RA, Spinas GA, Arkhammar PO, Mandrup-Poulsen T, Donath MY.
    Diabetes; 2004 Jul; 53(7):1706-13. PubMed ID: 15220194
    [Abstract] [Full Text] [Related]

  • 6. Diazoxide enhances basal metabolic rate and fat oxidation in obese Zucker rats.
    Alemzadeh R, Karlstad MD, Tushaus K, Buchholz M.
    Metabolism; 2008 Nov; 57(11):1597-607. PubMed ID: 18940400
    [Abstract] [Full Text] [Related]

  • 7. The effects of NN414, a SUR1/Kir6.2 selective potassium channel opener, in healthy male subjects.
    Zdravkovic M, Kruse M, Rost KL, Møss J, Kecskes A, Dyrberg T.
    J Clin Pharmacol; 2005 Jul; 45(7):763-72. PubMed ID: 15951466
    [Abstract] [Full Text] [Related]

  • 8. Induction of beta-cell rest by a Kir6.2/SUR1-selective K(ATP)-channel opener preserves beta-cell insulin stores and insulin secretion in human islets cultured at high (11 mM) glucose.
    Ritzel RA, Hansen JB, Veldhuis JD, Butler PC.
    J Clin Endocrinol Metab; 2004 Feb; 89(2):795-805. PubMed ID: 14764798
    [Abstract] [Full Text] [Related]

  • 9. Potent and selective activation of the pancreatic beta-cell type K(ATP) channel by two novel diazoxide analogues.
    Dabrowski M, Larsen T, Ashcroft FM, Bondo Hansen J, Wahl P.
    Diabetologia; 2003 Oct; 46(10):1375-82. PubMed ID: 12961066
    [Abstract] [Full Text] [Related]

  • 10. Diazoxide down-regulates leptin and lipid metabolizing enzymes in adipose tissue of Zucker rats.
    Standridge M, Alemzadeh R, Zemel M, Koontz J, Moustaid-Moussa N.
    FASEB J; 2000 Mar; 14(3):455-60. PubMed ID: 10698960
    [Abstract] [Full Text] [Related]

  • 11. Effect of diazoxide on brain capillary insulin receptor binding and food intake in hyperphagic obese Zucker rats.
    Alemzadeh R, Holshouser S.
    Endocrinology; 1999 Jul; 140(7):3197-202. PubMed ID: 10385415
    [Abstract] [Full Text] [Related]

  • 12. Antiobesity effect of diazoxide in obese Zucker rats.
    Alemzadeh R, Jacobs W, Pitukcheewanont P.
    Metabolism; 1996 Mar; 45(3):334-41. PubMed ID: 8606640
    [Abstract] [Full Text] [Related]

  • 13. New 3-alkylamino-4H-thieno-1,2,4-thiadiazine 1,1-dioxide derivatives activate ATP-sensitive potassium channels of pancreatic beta cells.
    Nielsen FE, Ebdrup S, Jensen AF, Ynddal L, Bodvarsdottir TB, Stidsen C, Worsaae A, Boonen HC, Arkhammar PO, Fremming T, Wahl P, Kornø HT, Hansen JB.
    J Med Chem; 2006 Jul 13; 49(14):4127-39. PubMed ID: 16821773
    [Abstract] [Full Text] [Related]

  • 14. Some cannabinoid receptor ligands and their distomers are direct-acting openers of SUR1 K(ATP) channels.
    Lynch CJ, Zhou Q, Shyng SL, Heal DJ, Cheetham SC, Dickinson K, Gregory P, Firnges M, Nordheim U, Goshorn S, Reiche D, Turski L, Antel J.
    Am J Physiol Endocrinol Metab; 2012 Mar 01; 302(5):E540-51. PubMed ID: 22167524
    [Abstract] [Full Text] [Related]

  • 15. Improved beta-cell survival and reduced insulitis in a type 1 diabetic rat model after treatment with a beta-cell-selective K(ATP) channel opener.
    Skak K, Gotfredsen CF, Lundsgaard D, Hansen JB, Sturis J, Markholst H.
    Diabetes; 2004 Apr 01; 53(4):1089-95. PubMed ID: 15047626
    [Abstract] [Full Text] [Related]

  • 16. Modification of insulin resistance by diazoxide in obese Zucker rats.
    Alemzadeh R, Slonim AE, Zdanowicz MM, Maturo J.
    Endocrinology; 1993 Aug 01; 133(2):705-12. PubMed ID: 8344209
    [Abstract] [Full Text] [Related]

  • 17. Amplified hormonal counterregulatory responses to hypoglycemia in rats after systemic delivery of a SUR-1-selective K(+) channel opener?
    Fan X, Ding Y, Cheng H, Gram DX, Sherwin RS, McCrimmon RJ.
    Diabetes; 2008 Dec 01; 57(12):3327-34. PubMed ID: 18776135
    [Abstract] [Full Text] [Related]

  • 18. Diazoxide attenuates insulin secretion and hepatic lipogenesis in zucker diabetic fatty rats.
    Alemzadeh R, Tushaus K.
    Med Sci Monit; 2005 Dec 01; 11(12):BR439-48. PubMed ID: 16319780
    [Abstract] [Full Text] [Related]

  • 19. Antidiabetic activity of white skinned sweet potato (Ipomoea batatas L.) in obese Zucker fatty rats.
    Kusano S, Abe H.
    Biol Pharm Bull; 2000 Jan 01; 23(1):23-6. PubMed ID: 10706405
    [Abstract] [Full Text] [Related]

  • 20. Possible New Strategies for the Treatment of Congenital Hyperinsulinism.
    Sikimic J, Hoffmeister T, Gresch A, Kaiser J, Barthlen W, Wolke C, Wieland I, Lendeckel U, Krippeit-Drews P, Düfer M, Drews G.
    Front Endocrinol (Lausanne); 2020 Jan 01; 11():545638. PubMed ID: 33193079
    [Abstract] [Full Text] [Related]

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