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166 related items for PubMed ID: 15048093

  • 1. Overcoming resistance to gamma-rays in squamous carcinoma cells by poly-drug elevation of ceramide levels.
    Alphonse G, Bionda C, Aloy MT, Ardail D, Rousson R, Rodriguez-Lafrasse C.
    Oncogene; 2004 Apr 08; 23(15):2703-15. PubMed ID: 15048093
    [Abstract] [Full Text] [Related]

  • 2. Ceramide induces activation of the mitochondrial/caspases pathway in Jurkat and SCC61 cells sensitive to gamma-radiation but activation of this sequence is defective in radioresistant SQ20B cells.
    Alphonse G, Aloy MT, Broquet P, Gerard JP, Louisot P, Rousson R, Rodriguez-Lafrasse C.
    Int J Radiat Biol; 2002 Sep 08; 78(9):821-35. PubMed ID: 12428923
    [Abstract] [Full Text] [Related]

  • 3. Increasing endogenous ceramide using inhibitors of sphingolipid metabolism maximizes ionizing radiation-induced mitochondrial injury and apoptotic cell killing.
    Rodriguez-Lafrasse C, Alphonse G, Aloy MT, Ardail D, Gérard JP, Louisot P, Rousson R.
    Int J Cancer; 2002 Oct 20; 101(6):589-98. PubMed ID: 12237902
    [Abstract] [Full Text] [Related]

  • 4. Protective role of Hsp27 protein against gamma radiation-induced apoptosis and radiosensitization effects of Hsp27 gene silencing in different human tumor cells.
    Aloy MT, Hadchity E, Bionda C, Diaz-Latoud C, Claude L, Rousson R, Arrigo AP, Rodriguez-Lafrasse C.
    Int J Radiat Oncol Biol Phys; 2008 Feb 01; 70(2):543-53. PubMed ID: 17980509
    [Abstract] [Full Text] [Related]

  • 5. Ceramide triggers caspase activation during gamma-radiation-induced apoptosis of human glioma cells lacking functional p53.
    Hara S, Nakashima S, Kiyono T, Sawada M, Yoshimura S, Iwama T, Sakai N.
    Oncol Rep; 2004 Jul 01; 12(1):119-23. PubMed ID: 15201971
    [Abstract] [Full Text] [Related]

  • 6. Radioresistance of human carcinoma cells is correlated to a defect in raft membrane clustering.
    Bionda C, Hadchity E, Alphonse G, Chapet O, Rousson R, Rodriguez-Lafrasse C, Ardail D.
    Free Radic Biol Med; 2007 Sep 01; 43(5):681-94. PubMed ID: 17664132
    [Abstract] [Full Text] [Related]

  • 7. De novo C16- and C24-ceramide generation contributes to spontaneous neutrophil apoptosis.
    Seumois G, Fillet M, Gillet L, Faccinetto C, Desmet C, François C, Dewals B, Oury C, Vanderplasschen A, Lekeux P, Bureau F.
    J Leukoc Biol; 2007 Jun 01; 81(6):1477-86. PubMed ID: 17329567
    [Abstract] [Full Text] [Related]

  • 8. Molecular mechanisms of TNF-alpha-induced ceramide formation in human glioma cells: P53-mediated oxidant stress-dependent and -independent pathways.
    Sawada M, Kiyono T, Nakashima S, Shinoda J, Naganawa T, Hara S, Iwama T, Sakai N.
    Cell Death Differ; 2004 Sep 01; 11(9):997-1008. PubMed ID: 15131591
    [Abstract] [Full Text] [Related]

  • 9. Apoptosis induced by intracellular ceramide accumulation in MDA-MB-435 breast carcinoma cells is dependent on the generation of reactive oxygen species.
    Chan SY, Hilchie AL, Brown MG, Anderson R, Hoskin DW.
    Exp Mol Pathol; 2007 Feb 01; 82(1):1-11. PubMed ID: 16624283
    [Abstract] [Full Text] [Related]

  • 10. Ceramide and glutathione define two independently regulated pathways of cell death initiated by p53 in Molt-4 leukaemia cells.
    El-Assaad W, Kozhaya L, Araysi S, Panjarian S, Bitar FF, Baz E, El-Sabban ME, Dbaibo GS.
    Biochem J; 2003 Dec 15; 376(Pt 3):725-32. PubMed ID: 12967322
    [Abstract] [Full Text] [Related]

  • 11. Role of ceramide in mediating apoptosis of irradiated LNCaP prostate cancer cells.
    Kimura K, Markowski M, Edsall LC, Spiegel S, Gelmann EP.
    Cell Death Differ; 2003 Feb 15; 10(2):240-8. PubMed ID: 12700652
    [Abstract] [Full Text] [Related]

  • 12. Increase in ceramide level alters the lysosomal targeting of cathepsin D prior to onset of apoptosis in HT-29 colon cancer cells.
    De Stefanis D, Reffo P, Bonelli G, Baccino FM, Sala G, Ghidoni R, Codogno P, Isidoro C.
    Biol Chem; 2002 Jun 15; 383(6):989-99. PubMed ID: 12222689
    [Abstract] [Full Text] [Related]

  • 13. Ceramide is the key mediator of oxidative stress-induced apoptosis in retinal photoreceptor cells.
    Sanvicens N, Cotter TG.
    J Neurochem; 2006 Sep 15; 98(5):1432-44. PubMed ID: 16923157
    [Abstract] [Full Text] [Related]

  • 14. Participation of Fas-mediated apoptotic pathway in KB, a human head and neck squamous cell carcinoma cell line, after irradiation.
    Uno M, Otsuki T, Yata K, Fujii T, Sakaguchi H, Akisada T, Hiratsuka J, Imajo Y, Harada T.
    Int J Oncol; 2002 Mar 15; 20(3):617-22. PubMed ID: 11836578
    [Abstract] [Full Text] [Related]

  • 15. Modulation of ceramide metabolism in T-leukemia cell lines potentiates apoptosis induced by the cationic antimicrobial peptide bovine lactoferricin.
    Furlong SJ, Ridgway ND, Hoskin DW.
    Int J Oncol; 2008 Mar 15; 32(3):537-44. PubMed ID: 18292930
    [Abstract] [Full Text] [Related]

  • 16. Differential regulation of cell death in head and neck cell carcinoma through alteration of cholesterol levels in lipid rafts microdomains.
    Bionda C, Athias A, Poncet D, Alphonse G, Guezguez A, Gambert P, Rodriguez-Lafrasse C, Ardail D.
    Biochem Pharmacol; 2008 Feb 01; 75(3):761-72. PubMed ID: 17996216
    [Abstract] [Full Text] [Related]

  • 17. Oxidation of pyridine nucleotides during Fas- and ceramide-induced apoptosis in Jurkat cells: correlation with changes in mitochondria, glutathione depletion, intracellular acidification and caspase 3 activation.
    Gendron MC, Schrantz N, Métivier D, Kroemer G, Maciorowska Z, Sureau F, Koester S, Petit PX.
    Biochem J; 2001 Jan 15; 353(Pt 2):357-67. PubMed ID: 11139401
    [Abstract] [Full Text] [Related]

  • 18. Ceramide induces early and late apoptosis in human papilloma virus+ cervical cancer cells by inhibiting reactive oxygen species decay, diminishing the intracellular concentration of glutathione and increasing nuclear factor-kappaB translocation.
    Gutiérrez G, Mendoza C, Montaño LF, López-Marure R.
    Anticancer Drugs; 2007 Feb 15; 18(2):149-59. PubMed ID: 17159601
    [Abstract] [Full Text] [Related]

  • 19. Hyperthermia engages the intrinsic apoptotic pathway by enhancing upstream caspase activation to overcome apoptotic resistance in MCF-7 breast adenocarcinoma cells.
    Klostergaard J, Leroux ME, Auzenne E, Khodadadian M, Spohn W, Wu JY, Donato NJ.
    J Cell Biochem; 2006 May 15; 98(2):356-69. PubMed ID: 16440323
    [Abstract] [Full Text] [Related]

  • 20. Sensitization for gamma-irradiation-induced apoptosis by second mitochondria-derived activator of caspase.
    Giagkousiklidis S, Vogler M, Westhoff MA, Kasperczyk H, Debatin KM, Fulda S.
    Cancer Res; 2005 Nov 15; 65(22):10502-13. PubMed ID: 16288043
    [Abstract] [Full Text] [Related]

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