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403 related items for PubMed ID: 15049127

  • 1. [Research and development of the free radical scavenger edaravone as a neuroprotectant].
    Watanabe T, Tanaka M, Watanabe K, Takamatsu Y, Tobe A.
    Yakugaku Zasshi; 2004 Mar; 124(3):99-111. PubMed ID: 15049127
    [Abstract] [Full Text] [Related]

  • 2. [Pharmacological and clinical profile of the free radical scavenger edaravone as a neuroprotective agent].
    Tanaka M.
    Nihon Yakurigaku Zasshi; 2002 May; 119(5):301-8. PubMed ID: 12061142
    [Abstract] [Full Text] [Related]

  • 3. Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury.
    Yoshida H, Yanai H, Namiki Y, Fukatsu-Sasaki K, Furutani N, Tada N.
    CNS Drug Rev; 2006 May; 12(1):9-20. PubMed ID: 16834755
    [Abstract] [Full Text] [Related]

  • 4. Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases.
    Higashi Y, Jitsuiki D, Chayama K, Yoshizumi M.
    Recent Pat Cardiovasc Drug Discov; 2006 Jan; 1(1):85-93. PubMed ID: 18221078
    [Abstract] [Full Text] [Related]

  • 5. The synergetic effect of edaravone and borneol in the rat model of ischemic stroke.
    Wu HY, Tang Y, Gao LY, Sun WX, Hua Y, Yang SB, Zhang ZP, Liao GY, Zhou QG, Luo CX, Zhu DY.
    Eur J Pharmacol; 2014 Oct 05; 740():522-31. PubMed ID: 24975100
    [Abstract] [Full Text] [Related]

  • 6. Radical scavenger edaravone developed for clinical use ameliorates ischemia/reperfusion injury in rat kidney.
    Doi K, Suzuki Y, Nakao A, Fujita T, Noiri E.
    Kidney Int; 2004 May 05; 65(5):1714-23. PubMed ID: 15086910
    [Abstract] [Full Text] [Related]

  • 7. Edaravone, a free radical scavenger, protects against retinal damage in vitro and in vivo.
    Inokuchi Y, Imai S, Nakajima Y, Shimazawa M, Aihara M, Araie M, Hara H.
    J Pharmacol Exp Ther; 2009 May 05; 329(2):687-98. PubMed ID: 19201991
    [Abstract] [Full Text] [Related]

  • 8. Free radical trapping as a therapeutic approach to neuroprotection in stroke: experimental and clinical studies with NXY-059 and free radical scavengers.
    Green AR, Ashwood T.
    Curr Drug Targets CNS Neurol Disord; 2005 Apr 05; 4(2):109-18. PubMed ID: 15857295
    [Abstract] [Full Text] [Related]

  • 9. Edaravone prevented deteriorated cardiac function after myocardial ischemia-reperfusion via inhibiting lipid peroxidation in rat.
    Yagi H, Horinaka S, Matsuoka H.
    J Cardiovasc Pharmacol; 2005 Jul 05; 46(1):46-51. PubMed ID: 15965354
    [Abstract] [Full Text] [Related]

  • 10. Edaravone attenuates white matter lesions through endothelial protection in a rat chronic hypoperfusion model.
    Ueno Y, Zhang N, Miyamoto N, Tanaka R, Hattori N, Urabe T.
    Neuroscience; 2009 Aug 18; 162(2):317-27. PubMed ID: 19409967
    [Abstract] [Full Text] [Related]

  • 11. Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain.
    Zhang N, Komine-Kobayashi M, Tanaka R, Liu M, Mizuno Y, Urabe T.
    Stroke; 2005 Oct 18; 36(10):2220-5. PubMed ID: 16166574
    [Abstract] [Full Text] [Related]

  • 12. Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage.
    Nakamura T, Kuroda Y, Yamashita S, Zhang X, Miyamoto O, Tamiya T, Nagao S, Xi G, Keep RF, Itano T.
    Stroke; 2008 Feb 18; 39(2):463-9. PubMed ID: 18096835
    [Abstract] [Full Text] [Related]

  • 13. A free radical scavenger edaravone suppresses systemic inflammatory responses in a rat transient focal ischemia model.
    Fujiwara N, Som AT, Pham LD, Lee BJ, Mandeville ET, Lo EH, Arai K.
    Neurosci Lett; 2016 Oct 28; 633():7-13. PubMed ID: 27589890
    [Abstract] [Full Text] [Related]

  • 14. The novel antioxidant edaravone: from bench to bedside.
    Watanabe T, Tahara M, Todo S.
    Cardiovasc Ther; 2008 Oct 28; 26(2):101-14. PubMed ID: 18485133
    [Abstract] [Full Text] [Related]

  • 15. Edaravone for the treatment of acute cerebral infarction: role of endothelium-derived nitric oxide and oxidative stress.
    Higashi Y.
    Expert Opin Pharmacother; 2009 Feb 28; 10(2):323-31. PubMed ID: 19236202
    [Abstract] [Full Text] [Related]

  • 16. The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells.
    Kikuchi K, Kawahara K, Tancharoen S, Matsuda F, Morimoto Y, Ito T, Biswas KK, Takenouchi K, Miura N, Oyama Y, Nawa Y, Arimura N, Iwata M, Tajima Y, Kuramoto T, Nakayama K, Shigemori M, Yoshida Y, Hashiguchi T, Maruyama I.
    J Pharmacol Exp Ther; 2009 Jun 28; 329(3):865-74. PubMed ID: 19293391
    [Abstract] [Full Text] [Related]

  • 17. Neuroprotective effects of edaravone on cognitive deficit, oxidative stress and tau hyperphosphorylation induced by intracerebroventricular streptozotocin in rats.
    Zhou S, Yu G, Chi L, Zhu J, Zhang W, Zhang Y, Zhang L.
    Neurotoxicology; 2013 Sep 28; 38():136-45. PubMed ID: 23932983
    [Abstract] [Full Text] [Related]

  • 18. Free-radical scavenger edaravone treatment confers neuroprotection against traumatic brain injury in rats.
    Wang GH, Jiang ZL, Li YC, Li X, Shi H, Gao YQ, Vosler PS, Chen J.
    J Neurotrauma; 2011 Oct 28; 28(10):2123-34. PubMed ID: 21732763
    [Abstract] [Full Text] [Related]

  • 19. Inhibitory effect of MCI-186, a free radical scavenger, on cerebral ischemia following rat middle cerebral artery occlusion.
    Mizuno A, Umemura K, Nakashima M.
    Gen Pharmacol; 1998 Apr 28; 30(4):575-8. PubMed ID: 9522178
    [Abstract] [Full Text] [Related]

  • 20. Edaravone, a free radical scavenger, attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia.
    Okamura K, Tsubokawa T, Johshita H, Miyazaki H, Shiokawa Y.
    Neurol Res; 2014 Jan 28; 36(1):65-9. PubMed ID: 24074041
    [Abstract] [Full Text] [Related]

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