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Journal Abstract Search

132 related items for PubMed ID: 15050617

  • 1. Subtype-selective nicotinic receptor antagonists: potential as tobacco use cessation agents.
    Dwoskin LP, Sumithran SP, Zhu J, Deaciuc AG, Ayers JT, Crooks PA.
    Bioorg Med Chem Lett; 2004 Apr 19; 14(8):1863-7. PubMed ID: 15050617
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  • 2. N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity.
    Dwoskin LP, Wooters TE, Sumithran SP, Siripurapu KB, Joyce BM, Lockman PR, Manda VK, Ayers JT, Zhang Z, Deaciuc AG, McIntosh JM, Crooks PA, Bardo MT.
    J Pharmacol Exp Ther; 2008 Aug 19; 326(2):563-76. PubMed ID: 18460644
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  • 3. N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonists: interaction with alpha4beta2* and alpha7* neuronal nicotinic receptors.
    Wilkins LH, Grinevich VP, Ayers JT, Crooks PA, Dwoskin LP.
    J Pharmacol Exp Ther; 2003 Jan 19; 304(1):400-10. PubMed ID: 12490617
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  • 6. The effects of a novel nicotinic receptor antagonist N,N-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) on acute and repeated nicotine-induced increases in extracellular dopamine in rat nucleus accumbens.
    Rahman S, Neugebauer NM, Zhang Z, Crooks PA, Dwoskin LP, Bardo MT.
    Neuropharmacology; 2007 Mar 19; 52(3):755-63. PubMed ID: 17097117
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  • 9. Region-specific effects of N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopamine in vivo.
    Rahman S, Zhang Z, Papke RL, Crooks PA, Dwoskin LP, Bardo MT.
    Br J Pharmacol; 2008 Feb 19; 153(4):792-804. PubMed ID: 18059317
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  • 10. Bupropion inhibits nicotine-evoked [(3)H]overflow from rat striatal slices preloaded with [(3)H]dopamine and from rat hippocampal slices preloaded with [(3)H]norepinephrine.
    Miller DK, Sumithran SP, Dwoskin LP.
    J Pharmacol Exp Ther; 2002 Sep 19; 302(3):1113-22. PubMed ID: 12183670
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  • 11. bPiDI: a novel selective α6β2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse.
    Wooters TE, Smith AM, Pivavarchyk M, Siripurapu KB, McIntosh JM, Zhang Z, Crooks PA, Bardo MT, Dwoskin LP.
    Br J Pharmacol; 2011 May 19; 163(2):346-57. PubMed ID: 21232049
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  • 12. Introduction of unsaturation into the N-n-alkyl chain of the nicotinic receptor antagonists, NONI and NDNI: effect on affinity and selectivity.
    Sumithran SP, Crooks PA, Xu R, Zhu J, Deaciuc AG, Wilkins LH, Dwoskin LP.
    AAPS J; 2005 Aug 29; 7(1):E201-17. PubMed ID: 16146341
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  • 15. Repeated nicotine administration robustly increases bPiDDB inhibitory potency at alpha6beta2-containing nicotinic receptors mediating nicotine-evoked dopamine release.
    Smith AM, Pivavarchyk M, Wooters TE, Zhang Z, Zheng G, McIntosh JM, Crooks PA, Bardo MT, Dwoskin LP.
    Biochem Pharmacol; 2010 Aug 01; 80(3):402-9. PubMed ID: 20346923
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  • 16. Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats.
    Neugebauer NM, Zhang Z, Crooks PA, Dwoskin LP, Bardo MT.
    Psychopharmacology (Berl); 2006 Mar 01; 184(3-4):426-34. PubMed ID: 16220336
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  • 18. Nicotinic receptor subtypes in rat hippocampal slices are differentially sensitive to desensitization and early in vivo functional up-regulation by nicotine and to block by bupropion.
    Alkondon M, Albuquerque EX.
    J Pharmacol Exp Ther; 2005 May 01; 313(2):740-50. PubMed ID: 15647329
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  • 19. Bis-azaaromatic quaternary ammonium salts as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release: An investigation of binding conformation.
    Zheng G, Zhang Z, Pivavarchyk M, Deaciuc AG, Dwoskin LP, Crooks PA.
    Bioorg Med Chem Lett; 2007 Dec 15; 17(24):6734-8. PubMed ID: 18029180
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  • 20. Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes.
    Carroll FI, Hu X, Navarro HA, Deschamps J, Abdrakhmanova GR, Damaj MI, Martin BR.
    J Med Chem; 2006 Jun 01; 49(11):3244-50. PubMed ID: 16722642
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