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103 related items for PubMed ID: 15053863

  • 1. Cloning and expression of canine O6-methylguanine-DNA methyltransferase in target cells, using gammaretroviral and lentiviral vectors.
    Zaboikin M, Srinivasakumar N, Zaboikina T, Schuening F.
    Hum Gene Ther; 2004 Apr; 15(4):383-92. PubMed ID: 15053863
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  • 2. Direct reversal of DNA damage by mutant methyltransferase protein protects mice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells.
    Ragg S, Xu-Welliver M, Bailey J, D'Souza M, Cooper R, Chandra S, Seshadri R, Pegg AE, Williams DA.
    Cancer Res; 2000 Sep 15; 60(18):5187-95. PubMed ID: 11016647
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  • 4. Retroviral-mediated expression of the P140A, but not P140A/G156A, mutant form of O6-methylguanine DNA methyltransferase protects hematopoietic cells against O6-benzylguanine sensitization to chloroethylnitrosourea treatment.
    Maze R, Kurpad C, Pegg AE, Erickson LC, Williams DA.
    J Pharmacol Exp Ther; 1999 Sep 15; 290(3):1467-74. PubMed ID: 10454526
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  • 5. Lentiviral transduction of P140K MGMT into human CD34(+) hematopoietic progenitors at low multiplicity of infection confers significant resistance to BG/BCNU and allows selection in vitro.
    Zielske SP, Gerson SL.
    Mol Ther; 2002 Apr 15; 5(4):381-7. PubMed ID: 11945064
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  • 6. G156A MGMT-transduced human mesenchymal stem cells can be selectively enriched by O6-benzylguanine and BCNU.
    Lee K, Gerson SL, Maitra B, Koç ON.
    J Hematother Stem Cell Res; 2001 Oct 15; 10(5):691-701. PubMed ID: 11672516
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  • 7. In vivo selection of MGMT(P140K) lentivirus-transduced human NOD/SCID repopulating cells without pretransplant irradiation conditioning.
    Zielske SP, Reese JS, Lingas KT, Donze JR, Gerson SL.
    J Clin Invest; 2003 Nov 15; 112(10):1561-70. PubMed ID: 14617757
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  • 8. Drug selection of mutant methylguanine methyltransferase from different oncoretroviral backbones results in multilineage hematopoietic transgene expression in primary and secondary recipients.
    Davis BM, Reese JS, Lingas K, Gerson SL.
    J Hematother Stem Cell Res; 2003 Aug 15; 12(4):375-87. PubMed ID: 12965075
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  • 9. Lentivirus-mediated expression of mutant MGMTP140K protects human CD34+ cells against the combined toxicity of O6-benzylguanine and 1,3-bis(2-chloroethyl)-nitrosourea or temozolomide.
    Chinnasamy D, Fairbairn LJ, Neuenfeldt J, Treisman JS, Hanson JP, Margison GP, Chinnasamy N.
    Hum Gene Ther; 2004 Aug 15; 15(8):758-69. PubMed ID: 15319033
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  • 10. A bicistronic SIN-lentiviral vector containing G156A MGMT allows selection and metabolic correction of hematopoietic protoporphyric cell lines.
    Richard E, Géronimi F, Lalanne M, Ged C, Redonnet-Vernhet I, Lamrissi-Garcia I, Gerson SL, de Verneuil H, Moreau-Gaudry F.
    J Gene Med; 2003 Sep 15; 5(9):737-47. PubMed ID: 12950064
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  • 12. In vivo selection for human and murine hematopoietic cells transduced with a therapeutic MGMT lentiviral vector that inhibits HIV replication.
    Davis BM, Humeau L, Dropulic B.
    Mol Ther; 2004 Feb 15; 9(2):160-72. PubMed ID: 14759800
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  • 14. Characterisation of a P140K mutant O6-methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow.
    Kramer BA, Lemckert FA, Alexander IE, Gunning PW, McCowage GB.
    J Gene Med; 2006 Sep 15; 8(9):1071-85. PubMed ID: 16927363
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  • 17. Bone marrow-derived cells exhibiting lung epithelial cell characteristics are enriched in vivo using methylguanine DNA methyltransferase-mediated drug resistance.
    Reese JS, Roth JC, Gerson SL.
    Stem Cells; 2008 Mar 15; 26(3):675-81. PubMed ID: 18192231
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  • 18. Retrovirus-mediated transfer of the human O6-methylguanine-DNA methyltransferase gene into a murine hematopoietic stem cell line and resistance to the toxic effects of certain alkylating agents.
    Wang G, Weiss C, Sheng P, Bresnick E.
    Biochem Pharmacol; 1996 May 03; 51(9):1221-8. PubMed ID: 8645346
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  • 19. Equal potency of gammaretroviral and lentiviral SIN vectors for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells.
    Schambach A, Bohne J, Chandra S, Will E, Margison GP, Williams DA, Baum C.
    Mol Ther; 2006 Feb 03; 13(2):391-400. PubMed ID: 16226060
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  • 20. Protection of hematopoietic cells against combined O6-benzylguanine and chloroethylnitrosourea treatment by mutant forms of O6-methylguanine DNA methyltransferase.
    Williams DA, Maze R, Kurpad C, Pegg A, Erickson LC.
    Bone Marrow Transplant; 2000 May 03; 25 Suppl 2():S105-9. PubMed ID: 10933201
    [Abstract] [Full Text] [Related]

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