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444 related items for PubMed ID: 15056007

  • 1. Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 2.
    Tsuzuki Y, Tomita K, Shibamori K, Sato Y, Kashimoto S, Chiba K.
    J Med Chem; 2004 Apr 08; 47(8):2097-109. PubMed ID: 15056007
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 1.
    Tomita K, Tsuzuki Y, Shibamori K, Tashima M, Kajikawa F, Sato Y, Kashimoto S, Chiba K, Hino K.
    J Med Chem; 2002 Dec 05; 45(25):5564-75. PubMed ID: 12459024
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and structure-activity relationships of 3-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridines as novel antitumor agents.
    Tsuzuki Y, Tomita K, Sato Y, Kashimoto S, Chiba K.
    Bioorg Med Chem Lett; 2004 Jun 21; 14(12):3189-93. PubMed ID: 15149673
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and cytotoxic activity of carboxamide derivatives of benzo[b][1,6]naphthyridines.
    Deady LW, Rodemann T, Zhuang L, Baguley BC, Denny WA.
    J Med Chem; 2003 Mar 13; 46(6):1049-54. PubMed ID: 12620081
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and cytotoxic activity of carboxamide derivatives of benzo[b][1,6]naphthyridin-(5H)ones.
    Deady LW, Rogers ML, Zhuang L, Baguley BC, Denny WA.
    Bioorg Med Chem; 2005 Feb 15; 13(4):1341-55. PubMed ID: 15670942
    [Abstract] [Full Text] [Related]

  • 6. Anticancer and immunomodulatory activities of novel 1,8-naphthyridine derivatives.
    Kumar V, Madaan A, Sanna VK, Vishnoi M, Joshi N, Singh AT, Jaggi M, Sharma PK, Irchhaiya R, Burman AC.
    J Enzyme Inhib Med Chem; 2009 Oct 15; 24(5):1169-78. PubMed ID: 19555167
    [Abstract] [Full Text] [Related]

  • 7. Antitumor efficiency of novel fluoro-substituted 6-amino-2-phenylbenzothiazole hydrochloride salts in vitro and in vivo.
    Stojkovic R, Karminski-Zamola G, Racane L, Tralic-Kulenovic V, Glavas-Obrovac L, Ivankovic S, Radacic M.
    Methods Find Exp Clin Pharmacol; 2006 Oct 15; 28(6):347-54. PubMed ID: 16894403
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and biological study of a new series of 4'-demethylepipodophyllotoxin derivatives.
    Duca M, Guianvarc'h D, Meresse P, Bertounesque E, Dauzonne D, Kraus-Berthier L, Thirot S, Léonce S, Pierré A, Pfeiffer B, Renard P, Arimondo PB, Monneret C.
    J Med Chem; 2005 Jan 27; 48(2):593-603. PubMed ID: 15658872
    [Abstract] [Full Text] [Related]

  • 9. Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives.
    Sztanke K, Tuzimski T, Rzymowska J, Pasternak K, Kandefer-Szerszeń M.
    Eur J Med Chem; 2008 Feb 27; 43(2):404-19. PubMed ID: 17531354
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and cytostatic properties of some 6H-Indolo[2, 3-b][1, 8]naphthyridine derivatives.
    Mastalarz H, Jasztold-Howorko R, Rulko F, Croisy A, Carrez D.
    Arch Pharm (Weinheim); 2004 Aug 27; 337(8):434-9. PubMed ID: 15293262
    [Abstract] [Full Text] [Related]

  • 11. Novel fluoroquinolone antibacterial agents containing oxime-substituted (aminomethyl)pyrrolidines: synthesis and antibacterial activity of 7-(4-(aminomethyl)-3-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl-6- fluoro-4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid (LB20304).
    Hong CY, Kim YK, Chang JH, Kim SH, Choi H, Nam DH, Kim YZ, Kwak JH.
    J Med Chem; 1997 Oct 24; 40(22):3584-93. PubMed ID: 9357525
    [Abstract] [Full Text] [Related]

  • 12. Antitumor agents. 174. 2',3',4',5,6,7-Substituted 2-phenyl-1,8-naphthyridin-4-ones: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
    Chen K, Kuo SC, Hsieh MC, Mauger A, Lin CM, Hamel E, Lee KH.
    J Med Chem; 1997 Jul 04; 40(14):2266-75. PubMed ID: 9216846
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and antitumor activity of novel pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5-one derivatives.
    El-Nassan HB.
    Eur J Med Chem; 2011 Jun 04; 46(6):2031-6. PubMed ID: 21429629
    [Abstract] [Full Text] [Related]

  • 14. Quinols as novel therapeutic agents. 2.(1) 4-(1-Arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones and related agents as potent and selective antitumor agents.
    Berry JM, Bradshaw TD, Fichtner I, Ren R, Schwalbe CH, Wells G, Chew EH, Stevens MF, Westwell AD.
    J Med Chem; 2005 Jan 27; 48(2):639-44. PubMed ID: 15658878
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and in-vitro cytotoxic evaluation of novel pyridazin-4-one derivatives.
    Mojahidi S, Rakib el M, Sekkak H, Abouricha S, Benchat N, Mousse HA, Zyad A.
    Arch Pharm (Weinheim); 2010 May 27; 343(5):310-3. PubMed ID: 20222064
    [Abstract] [Full Text] [Related]

  • 16. Antineoplastic agents 491. Synthetic conversion of aaptamine to isoaaptamine, 9-demethylaaptamine, and 4-methylaaptamine.
    Pettit GR, Hoffmann H, Herald DL, McNulty J, Murphy A, Higgs KC, Hamel E, Lewin NE, Pearce LV, Blumberg PM, Pettit RK, Knight JC.
    J Org Chem; 2004 Apr 02; 69(7):2251-6. PubMed ID: 15049616
    [Abstract] [Full Text] [Related]

  • 17. Synthesis of novel thiazolyl-pyrimidines and their anticancer activity in vitro.
    Shi HB, Li HB, Lu KQ, Zhu XR, Hu WX, Pei W.
    Arch Pharm (Weinheim); 2011 Oct 02; 344(10):675-83. PubMed ID: 21984017
    [Abstract] [Full Text] [Related]

  • 18. Voreloxin, formerly SNS-595, has potent activity against a broad panel of cancer cell lines and in vivo tumor models.
    Hoch U, Lynch J, Sato Y, Kashimoto S, Kajikawa F, Furutani Y, Silverman JA.
    Cancer Chemother Pharmacol; 2009 Jun 02; 64(1):53-65. PubMed ID: 18931998
    [Abstract] [Full Text] [Related]

  • 19. Antitumor activity of imidazothioxanthones in murine and human tumor models in vitro and in vivo.
    Varvaresou A, Iakovou K, Gikas E, Fichtner I, Fiebig HH, Kelland LR, Double JA, Bibby MC, Hendriks HR.
    Anticancer Res; 2004 Jun 02; 24(2B):907-19. PubMed ID: 15161044
    [Abstract] [Full Text] [Related]

  • 20. Anti-inflammatory activity of a naphthyridine derivative (7-chloro-6-fluoro-N-(2-hydroxy-3-oxo-1-phenyl-3-(phenylamino)propyl)-4-oxo-1-(prop-2-yn-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxamide) possessing in vitro anticancer potential.
    Madaan A, Kumar V, Verma R, Singh AT, Jain SK, Jaggi M.
    Int Immunopharmacol; 2013 Mar 02; 15(3):606-13. PubMed ID: 23370301
    [Abstract] [Full Text] [Related]

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