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264 related items for PubMed ID: 15056668

  • 1. Interferon alpha-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway.
    Thyrell L, Hjortsberg L, Arulampalam V, Panaretakis T, Uhles S, Dagnell M, Zhivotovsky B, Leibiger I, Grandér D, Pokrovskaja K.
    J Biol Chem; 2004 Jun 04; 279(23):24152-62. PubMed ID: 15056668
    [Abstract] [Full Text] [Related]

  • 2. Prolactin activates mammalian target-of-rapamycin through phosphatidylinositol 3-kinase and stimulates phosphorylation of p70S6K and 4E-binding protein-1 in lymphoma cells.
    Bishop JD, Nien WL, Dauphinee SM, Too CK.
    J Endocrinol; 2006 Aug 04; 190(2):307-12. PubMed ID: 16899564
    [Abstract] [Full Text] [Related]

  • 3. Interferon alpha induces nucleus-independent apoptosis by activating extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase downstream of phosphatidylinositol 3-kinase and mammalian target of rapamycin.
    Panaretakis T, Hjortsberg L, Tamm KP, Björklund AC, Joseph B, Grandér D.
    Mol Biol Cell; 2008 Jan 04; 19(1):41-50. PubMed ID: 17942603
    [Abstract] [Full Text] [Related]

  • 4. Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons.
    Lekmine F, Uddin S, Sassano A, Parmar S, Brachmann SM, Majchrzak B, Sonenberg N, Hay N, Fish EN, Platanias LC.
    J Biol Chem; 2003 Jul 25; 278(30):27772-80. PubMed ID: 12759354
    [Abstract] [Full Text] [Related]

  • 5. Strain-induced vascular endothelial cell proliferation requires PI3K-dependent mTOR-4E-BP1 signal pathway.
    Li W, Sumpio BE.
    Am J Physiol Heart Circ Physiol; 2005 Apr 25; 288(4):H1591-7. PubMed ID: 15591103
    [Abstract] [Full Text] [Related]

  • 6. Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells.
    Ikezoe T, Nishioka C, Bandobashi K, Yang Y, Kuwayama Y, Adachi Y, Takeuchi T, Koeffler HP, Taguchi H.
    Leuk Res; 2007 May 25; 31(5):673-82. PubMed ID: 17007924
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  • 7. Constitutive activation of phosphatidyl-inositide 3 kinase contributes to the survival of Hodgkin's lymphoma cells through a mechanism involving Akt kinase and mTOR.
    Dutton A, Reynolds GM, Dawson CW, Young LS, Murray PG.
    J Pathol; 2005 Mar 25; 205(4):498-506. PubMed ID: 15714459
    [Abstract] [Full Text] [Related]

  • 8. Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.
    Gulati N, Karsy M, Albert L, Murali R, Jhanwar-Uniyal M.
    Int J Oncol; 2009 Oct 25; 35(4):731-40. PubMed ID: 19724909
    [Abstract] [Full Text] [Related]

  • 9. G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells.
    Gao N, Flynn DC, Zhang Z, Zhong XS, Walker V, Liu KJ, Shi X, Jiang BH.
    Am J Physiol Cell Physiol; 2004 Aug 25; 287(2):C281-91. PubMed ID: 15028555
    [Abstract] [Full Text] [Related]

  • 10. Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
    Vega F, Medeiros LJ, Leventaki V, Atwell C, Cho-Vega JH, Tian L, Claret FX, Rassidakis GZ.
    Cancer Res; 2006 Jul 01; 66(13):6589-97. PubMed ID: 16818631
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of phosphatidylinositol 3-kinase- and ERK MAPK-regulated protein synthesis reveals the pro-apoptotic properties of CD40 ligation in carcinoma cells.
    Davies CC, Mason J, Wakelam MJ, Young LS, Eliopoulos AG.
    J Biol Chem; 2004 Jan 09; 279(2):1010-9. PubMed ID: 14581487
    [Abstract] [Full Text] [Related]

  • 12. ANG II activates effectors of mTOR via PI3-K signaling in human coronary smooth muscle cells.
    Hafizi S, Wang X, Chester AH, Yacoub MH, Proud CG.
    Am J Physiol Heart Circ Physiol; 2004 Sep 09; 287(3):H1232-8. PubMed ID: 15317677
    [Abstract] [Full Text] [Related]

  • 13. Differential regulation of the p70 S6 kinase pathway by interferon alpha (IFNalpha) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells.
    Parmar S, Smith J, Sassano A, Uddin S, Katsoulidis E, Majchrzak B, Kambhampati S, Eklund EA, Tallman MS, Fish EN, Platanias LC.
    Blood; 2005 Oct 01; 106(7):2436-43. PubMed ID: 15790787
    [Abstract] [Full Text] [Related]

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  • 15. Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.
    Sun SY, Rosenberg LM, Wang X, Zhou Z, Yue P, Fu H, Khuri FR.
    Cancer Res; 2005 Aug 15; 65(16):7052-8. PubMed ID: 16103051
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  • 19. Phosphoinositide 3-kinase regulates a subset of interferon-alpha-stimulated genes.
    Hjortsberg L, Lindvall C, Corcoran M, Arulampalam V, Chan D, Thyrell L, Nordenskjold M, Grandér D, Pokrovskaja K.
    Exp Cell Res; 2007 Jan 15; 313(2):404-14. PubMed ID: 17141757
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