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156 related items for PubMed ID: 15072950

  • 1. Pharmacological rescue of trafficking defective HERG channels formed by coassembly of wild-type and long QT mutant N470D subunits.
    Gong Q, Anderson CL, January CT, Zhou Z.
    Am J Physiol Heart Circ Physiol; 2004 Aug; 287(2):H652-8. PubMed ID: 15072950
    [Abstract] [Full Text] [Related]

  • 2. Mechanisms of pharmacological rescue of trafficking-defective hERG mutant channels in human long QT syndrome.
    Gong Q, Jones MA, Zhou Z.
    J Biol Chem; 2006 Feb 17; 281(7):4069-74. PubMed ID: 16361248
    [Abstract] [Full Text] [Related]

  • 3. The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations.
    Ficker E, Obejero-Paz CA, Zhao S, Brown AM.
    J Biol Chem; 2002 Feb 15; 277(7):4989-98. PubMed ID: 11741928
    [Abstract] [Full Text] [Related]

  • 4. Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects.
    Zhou Z, Gong Q, January CT.
    J Biol Chem; 1999 Oct 29; 274(44):31123-6. PubMed ID: 10531299
    [Abstract] [Full Text] [Related]

  • 5. Retention in the endoplasmic reticulum as a mechanism of dominant-negative current suppression in human long QT syndrome.
    Ficker E, Dennis AT, Obejero-Paz CA, Castaldo P, Taglialatela M, Brown AM.
    J Mol Cell Cardiol; 2000 Dec 29; 32(12):2327-37. PubMed ID: 11113008
    [Abstract] [Full Text] [Related]

  • 6. Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C.
    Delisle BP, Anderson CL, Balijepalli RC, Anson BD, Kamp TJ, January CT.
    J Biol Chem; 2003 Sep 12; 278(37):35749-54. PubMed ID: 12837749
    [Abstract] [Full Text] [Related]

  • 7. Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block.
    Rajamani S, Anderson CL, Anson BD, January CT.
    Circulation; 2002 Jun 18; 105(24):2830-5. PubMed ID: 12070109
    [Abstract] [Full Text] [Related]

  • 8. HERG-F463L potassium channels linked to long QT syndrome reduce I(Kr) current by a trafficking-deficient mechanism.
    Yang HT, Sun CF, Cui CC, Xue XL, Zhang AF, Li HB, Wang DQ, Shu J.
    Clin Exp Pharmacol Physiol; 2009 Aug 18; 36(8):822-7. PubMed ID: 19215240
    [Abstract] [Full Text] [Related]

  • 9. Defective assembly and trafficking of mutant HERG channels with C-terminal truncations in long QT syndrome.
    Gong Q, Keeney DR, Robinson JC, Zhou Z.
    J Mol Cell Cardiol; 2004 Dec 18; 37(6):1225-33. PubMed ID: 15572053
    [Abstract] [Full Text] [Related]

  • 10. Identification of a COOH-terminal segment involved in maturation and stability of human ether-a-go-go-related gene potassium channels.
    Akhavan A, Atanasiu R, Shrier A.
    J Biol Chem; 2003 Oct 10; 278(41):40105-12. PubMed ID: 12885765
    [Abstract] [Full Text] [Related]

  • 11. Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel.
    Furutani M, Trudeau MC, Hagiwara N, Seki A, Gong Q, Zhou Z, Imamura S, Nagashima H, Kasanuki H, Takao A, Momma K, January CT, Robertson GA, Matsuoka R.
    Circulation; 1999 May 04; 99(17):2290-4. PubMed ID: 10226095
    [Abstract] [Full Text] [Related]

  • 12. Clinical and electrophysiological characterization of a novel mutation R863X in HERG C-terminus associated with long QT syndrome.
    Teng S, Ma L, Dong Y, Lin C, Ye J, Bähring R, Vardanyan V, Yang Y, Lin Z, Pongs O, Hui R.
    J Mol Med (Berl); 2004 Mar 04; 82(3):189-96. PubMed ID: 14714110
    [Abstract] [Full Text] [Related]

  • 13. A novel mutation (T65P) in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency.
    Paulussen A, Raes A, Matthijs G, Snyders DJ, Cohen N, Aerssens J.
    J Biol Chem; 2002 Dec 13; 277(50):48610-6. PubMed ID: 12354768
    [Abstract] [Full Text] [Related]

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  • 15. Defective human Ether-à-go-go-related gene trafficking linked to an endoplasmic reticulum retention signal in the C terminus.
    Kupershmidt S, Yang T, Chanthaphaychith S, Wang Z, Towbin JA, Roden DM.
    J Biol Chem; 2002 Jul 26; 277(30):27442-8. PubMed ID: 12021266
    [Abstract] [Full Text] [Related]

  • 16. [The mechanistic rote of KCNH2 gene L413P and L559H mutations in long QT syndrome].
    Li CL, Hu DY, Liu WL, Qi SY, Wang HT, Li L, Gong QM, Zhou ZF.
    Zhonghua Nei Ke Za Zhi; 2007 Oct 26; 46(10):838-41. PubMed ID: 18218237
    [Abstract] [Full Text] [Related]

  • 17. The dominant negative LQT2 mutation A561V reduces wild-type HERG expression.
    Kagan A, Yu Z, Fishman GI, McDonald TV.
    J Biol Chem; 2000 Apr 14; 275(15):11241-8. PubMed ID: 10753933
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  • 20. Novel characteristics of a trafficking-defective G572R-hERG channel linked to hereditary long QT syndrome.
    Lian J, Huang N, Zhou J, Ge S, Huang X, Huo J, Liu L, Xu W, Zhang S, Yang X, Zhou J, Huang C.
    Can J Cardiol; 2010 Oct 14; 26(8):417-22. PubMed ID: 20931094
    [Abstract] [Full Text] [Related]

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