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Journal Abstract Search

366 related items for PubMed ID: 15073137

  • 1. Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts.
    Cao S, Durrani FA, Rustum YM.
    Clin Cancer Res; 2004 Apr 01; 10(7):2561-9. PubMed ID: 15073137
    [Abstract] [Full Text] [Related]

  • 2. Synergistic antitumor activity of capecitabine in combination with irinotecan.
    Cao S, Durrani FA, Rustum YM.
    Clin Colorectal Cancer; 2005 Jan 01; 4(5):336-43. PubMed ID: 15663838
    [Abstract] [Full Text] [Related]

  • 3. Selenium protects against toxicity induced by anticancer drugs and augments antitumor activity: a highly selective, new, and novel approach for the treatment of solid tumors.
    Fakih M, Cao S, Durrani FA, Rustum YM.
    Clin Colorectal Cancer; 2005 Jul 01; 5(2):132-5. PubMed ID: 16098255
    [Abstract] [Full Text] [Related]

  • 4. Hypoxia-specific drug tirapazamine does not abrogate hypoxic tumor cells in combination therapy with irinotecan and methylselenocysteine in well-differentiated human head and neck squamous cell carcinoma a253 xenografts.
    Bhattacharya A, Tóth K, Durrani FA, Cao S, Slocum HK, Chintala S, Rustum YM.
    Neoplasia; 2008 Aug 01; 10(8):857-65. PubMed ID: 18670644
    [Abstract] [Full Text] [Related]

  • 5. Efficacy of increasing the therapeutic index of irinotecan, plasma and tissue selenium concentrations is methylselenocysteine dose dependent.
    Azrak RG, Cao S, Pendyala L, Durrani FA, Fakih M, Combs GF, Prey J, Smith PF, Rustum YM.
    Biochem Pharmacol; 2007 May 01; 73(9):1280-7. PubMed ID: 17239826
    [Abstract] [Full Text] [Related]

  • 6. Antitumor activity of ZD1694 (tomudex) against human head and neck cancer in nude mouse models: role of dosing schedule and plasma thymidine.
    Cao S, McGuire JJ, Rustum YM.
    Clin Cancer Res; 1999 Jul 01; 5(7):1925-34. PubMed ID: 10430100
    [Abstract] [Full Text] [Related]

  • 7. Therapeutic synergy between irinotecan and 5-fluorouracil against human tumor xenografts.
    Azrak RG, Cao S, Slocum HK, Tóth K, Durrani FA, Yin MB, Pendyala L, Zhang W, McLeod HL, Rustum YM.
    Clin Cancer Res; 2004 Feb 01; 10(3):1121-9. PubMed ID: 14871992
    [Abstract] [Full Text] [Related]

  • 8. Irinotecan pharmacokinetic and pharmacogenomic alterations induced by methylselenocysteine in human head and neck xenograft tumors.
    Azrak RG, Yu J, Pendyala L, Smith PF, Cao S, Li X, Shannon WD, Durrani FA, McLeod HL, Rustum YM.
    Mol Cancer Ther; 2005 May 01; 4(5):843-54. PubMed ID: 15897249
    [Abstract] [Full Text] [Related]

  • 9. Se-methylselenocysteine offers selective protection against toxicity and potentiates the antitumour activity of anticancer drugs in preclinical animal models.
    Cao S, Durrani FA, Tóth K, Rustum YM.
    Br J Cancer; 2014 Apr 02; 110(7):1733-43. PubMed ID: 24619073
    [Abstract] [Full Text] [Related]

  • 10. Potentiation of irinotecan sensitivity by Se-methylselenocysteine in an in vivo tumor model is associated with downregulation of cyclooxygenase-2, inducible nitric oxide synthase, and hypoxia-inducible factor 1alpha expression, resulting in reduced angiogenesis.
    Yin MB, Li ZR, Tóth K, Cao S, Durrani FA, Hapke G, Bhattacharya A, Azrak RG, Frank C, Rustum YM.
    Oncogene; 2006 Apr 20; 25(17):2509-19. PubMed ID: 16518418
    [Abstract] [Full Text] [Related]

  • 11. Overexpression of Bax enhances antitumor activity of chemotherapeutic agents in human head and neck squamous cell carcinoma.
    Guo B, Cao S, Tóth K, Azrak RG, Rustum YM.
    Clin Cancer Res; 2000 Feb 20; 6(2):718-24. PubMed ID: 10690558
    [Abstract] [Full Text] [Related]

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  • 13. Augmented therapeutic efficacy of irinotecan is associated with enhanced drug accumulation.
    Azrak RG, Cao S, Durrani FA, Toth K, Bhattacharya A, Rustum YM.
    Cancer Lett; 2011 Dec 08; 311(2):219-29. PubMed ID: 21872389
    [Abstract] [Full Text] [Related]

  • 14. Efficacy of topoisomerase I inhibitors, topotecan and irinotecan, administered at low dose levels in protracted schedules to mice bearing xenografts of human tumors.
    Houghton PJ, Cheshire PJ, Hallman JD, Lutz L, Friedman HS, Danks MK, Houghton JA.
    Cancer Chemother Pharmacol; 1995 Dec 08; 36(5):393-403. PubMed ID: 7634381
    [Abstract] [Full Text] [Related]

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  • 16. Cytotoxicity and therapeutic effect of irinotecan combined with selenium nanoparticles.
    Gao F, Yuan Q, Gao L, Cai P, Zhu H, Liu R, Wang Y, Wei Y, Huang G, Liang J, Gao X.
    Biomaterials; 2014 Oct 08; 35(31):8854-8866. PubMed ID: 25064805
    [Abstract] [Full Text] [Related]

  • 17. Efficacy of oral irinotecan against neuroblastoma xenografts.
    Thompson J, Zamboni WC, Cheshire PJ, Richmond L, Luo X, Houghton JA, Stewart CF, Houghton PJ.
    Anticancer Drugs; 1997 Apr 08; 8(4):313-22. PubMed ID: 9180383
    [Abstract] [Full Text] [Related]

  • 18. Preclinical evaluation of the anticancer activity and toxicity of 9-nitro-20(S)-camptothecin (Rubitecan).
    Giovanella BC, Stehlin JS, Hinz HR, Kozielski AJ, Harris NJ, Vardeman DM.
    Int J Oncol; 2002 Jan 08; 20(1):81-8. PubMed ID: 11743646
    [Abstract] [Full Text] [Related]

  • 19. Antitumor activity of a camptothecin derivative, CPT-11, against human tumor xenografts in nude mice.
    Kawato Y, Furuta T, Aonuma M, Yasuoka M, Yokokura T, Matsumoto K.
    Cancer Chemother Pharmacol; 1991 Jan 08; 28(3):192-8. PubMed ID: 1855276
    [Abstract] [Full Text] [Related]

  • 20. Tumor vascular maturation and improved drug delivery induced by methylselenocysteine leads to therapeutic synergy with anticancer drugs.
    Bhattacharya A, Seshadri M, Oven SD, Tóth K, Vaughan MM, Rustum YM.
    Clin Cancer Res; 2008 Jun 15; 14(12):3926-32. PubMed ID: 18559614
    [Abstract] [Full Text] [Related]

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