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565 related items for PubMed ID: 15078986

  • 1. The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells.
    Zhang XD, Gillespie SK, Borrow JM, Hersey P.
    Mol Cancer Ther; 2004 Apr; 3(4):425-35. PubMed ID: 15078986
    [Abstract] [Full Text] [Related]

  • 2. Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells.
    Gillespie S, Borrow J, Zhang XD, Hersey P.
    Apoptosis; 2006 Dec; 11(12):2251-65. PubMed ID: 17051334
    [Abstract] [Full Text] [Related]

  • 3. The histone deacetylase inhibitor suberic bishydroxamate: a potential sensitizer of melanoma to TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis.
    Zhang XD, Gillespie SK, Borrow JM, Hersey P.
    Biochem Pharmacol; 2003 Oct 15; 66(8):1537-45. PubMed ID: 14555232
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  • 5. Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.
    Wang YF, Jiang CC, Kiejda KA, Gillespie S, Zhang XD, Hersey P.
    Clin Cancer Res; 2007 Aug 15; 13(16):4934-42. PubMed ID: 17652623
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  • 7. [Antitumor activity of histone deacetylase inhibitor suberic bishydroxamate on acute myeloid leukemia cell lines].
    Xu YH, Yang CM, Qian WB.
    Zhejiang Da Xue Xue Bao Yi Xue Ban; 2012 Sep 15; 41(5):491-7. PubMed ID: 23086640
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  • 8. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM.
    J Biol Chem; 2011 Mar 18; 286(11):9382-92. PubMed ID: 21148306
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  • 9. c-Myc overexpression sensitizes Bim-mediated Bax activation for apoptosis induced by histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through regulating Bcl-2/Bcl-xL expression.
    Jiang X, Tsang YH, Yu Q.
    Int J Biochem Cell Biol; 2007 Mar 18; 39(5):1016-25. PubMed ID: 17331788
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  • 11. Interferon-alpha-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax.
    Panaretakis T, Pokrovskaja K, Shoshan MC, Grandér D.
    Oncogene; 2003 Jul 17; 22(29):4543-56. PubMed ID: 12881711
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  • 13. Prometaphase arrest-dependent phosphorylation of Bcl-2 and Bim reduces the association of Bcl-2 with Bak or Bim, provoking Bak activation and mitochondrial apoptosis in nocodazole-treated Jurkat T cells.
    Han CR, Jun do Y, Lee JY, Kim YH.
    Apoptosis; 2014 Jan 17; 19(1):224-40. PubMed ID: 24166139
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  • 14. LIGHT sensitizes IFNgamma-mediated apoptosis of MDA-MB-231 breast cancer cells leading to down-regulation of anti-apoptosis Bcl-2 family members.
    Zhang M, Guo R, Zhai Y, Yang D.
    Cancer Lett; 2003 Jun 10; 195(2):201-10. PubMed ID: 12767529
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  • 15. Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.
    Boya P, Gonzalez-Polo RA, Poncet D, Andreau K, Vieira HL, Roumier T, Perfettini JL, Kroemer G.
    Oncogene; 2003 Jun 19; 22(25):3927-36. PubMed ID: 12813466
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  • 17. TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria.
    Thomas WD, Zhang XD, Franco AV, Nguyen T, Hersey P.
    J Immunol; 2000 Nov 15; 165(10):5612-20. PubMed ID: 11067917
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  • 19. Involvement of BH3-only proapoptotic proteins in mitochondrial-dependent Phenoxodiol-induced apoptosis of human melanoma cells.
    Yu F, Watts RN, Zhang XD, Borrow JM, Hersey P.
    Anticancer Drugs; 2006 Nov 15; 17(10):1151-61. PubMed ID: 17075314
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  • 20. Cotreatment with suberanoylanilide hydroxamic acid and 17-allylamino 17-demethoxygeldanamycin synergistically induces apoptosis in Bcr-Abl+ Cells sensitive and resistant to STI571 (imatinib mesylate) in association with down-regulation of Bcr-Abl, abrogation of signal transducer and activator of transcription 5 activity, and Bax conformational change.
    Rahmani M, Reese E, Dai Y, Bauer C, Kramer LB, Huang M, Jove R, Dent P, Grant S.
    Mol Pharmacol; 2005 Apr 15; 67(4):1166-76. PubMed ID: 15625278
    [Abstract] [Full Text] [Related]

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