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Journal Abstract Search

103 related items for PubMed ID: 15081012

  • 1. Thioxanthene-derived analogs as sigma(1) receptor ligands.
    Glennon RA, Ismaiel AM, Ablordeppey S, El-Ashmawy M, Fisher JB.
    Bioorg Med Chem Lett; 2004 May 03; 14(9):2217-20. PubMed ID: 15081012
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and structure-affinity relationships of novel spirocyclic sigma receptor ligands with furopyrazole structure.
    Schläger T, Schepmann D, Würthwein EU, Wünsch B.
    Bioorg Med Chem; 2008 Mar 15; 16(6):2992-3001. PubMed ID: 18221879
    [Abstract] [Full Text] [Related]

  • 3. Structure-activity comparison of YZ-069, a novel sigma ligand, and four analogs in receptor binding and behavioral studies.
    Matsumoto RR, Potelleret FH, Mack A, Pouw B, Zhang Y, Bowen WD.
    Pharmacol Biochem Behav; 2004 Apr 15; 77(4):775-81. PubMed ID: 15099923
    [Abstract] [Full Text] [Related]

  • 4. Synthesis, pharmacological activity and structure affinity relationships of spirocyclic σ(1) receptor ligands with a (2-fluoroethyl) residue in 3-position.
    Maestrup EG, Wiese C, Schepmann D, Brust P, Wünsch B.
    Bioorg Med Chem; 2011 Jan 01; 19(1):393-405. PubMed ID: 21126878
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and structure-activity relationships of 1-aralkyl-4-benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent sigma ligands.
    Costantino L, Gandolfi F, Sorbi C, Franchini S, Prezzavento O, Vittorio F, Ronsisvalle G, Leonardi A, Poggesi E, Brasili L.
    J Med Chem; 2005 Jan 13; 48(1):266-73. PubMed ID: 15634021
    [Abstract] [Full Text] [Related]

  • 6. 1,4-Diazepanes derived from (S)-serine--homopiperazines with improved sigma(1) (sigma) receptor affinity and selectivity.
    Bedürftig S, Wünsch B.
    Eur J Med Chem; 2009 Feb 13; 44(2):519-25. PubMed ID: 18499305
    [Abstract] [Full Text] [Related]

  • 7. Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling.
    Banister SD, Moussa IA, Jordan MJ, Coster MJ, Kassiou M.
    Bioorg Med Chem Lett; 2010 Jan 01; 20(1):145-8. PubMed ID: 19954972
    [Abstract] [Full Text] [Related]

  • 8. Substituted benzo[d]oxazol-2(3H)-one derivatives with preference for the sigma1 binding site.
    Zampieri D, Grazia Mamolo M, Laurini E, Zanette C, Florio C, Collina S, Rossi D, Azzolina O, Vio L.
    Eur J Med Chem; 2009 Jan 01; 44(1):124-30. PubMed ID: 18440098
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and structure-activity relationships of N-(3-phenylpropyl)-N'-benzylpiperazines: Potent ligands for sigma1 and sigma2 receptors.
    Nahas RI, Lever JR, Lever SZ.
    Bioorg Med Chem; 2008 Jan 15; 16(2):755-61. PubMed ID: 18029187
    [Abstract] [Full Text] [Related]

  • 10. A medicinal-chemistry-guided approach to selective and druglike sigma 1 ligands.
    Corbera J, Vaño D, Martínez D, Vela JM, Zamanillo D, Dordal A, Andreu F, Hernandez E, Perez R, Escriche M, Salgado L, Yeste S, Serafini MT, Pascual R, Alegre J, Calvet MC, Cano N, Carro M, Buschmann H, Holenz J.
    ChemMedChem; 2006 Jan 15; 1(1):140-54. PubMed ID: 16892345
    [Abstract] [Full Text] [Related]

  • 11. Conversion of a highly selective sigma-1 receptor-ligand to sigma-2 receptor preferring ligands with anticocaine activity.
    Mésangeau C, Narayanan S, Green AM, Shaikh J, Kaushal N, Viard E, Xu YT, Fishback JA, Poupaert JH, Matsumoto RR, McCurdy CR.
    J Med Chem; 2008 Mar 13; 51(5):1482-6. PubMed ID: 18278854
    [Abstract] [Full Text] [Related]

  • 12. Exploring the importance of piperazine N-atoms for sigma(2) receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28).
    Berardi F, Abate C, Ferorelli S, Uricchio V, Colabufo NA, Niso M, Perrone R.
    J Med Chem; 2009 Dec 10; 52(23):7817-28. PubMed ID: 19842660
    [Abstract] [Full Text] [Related]

  • 13. Synthesis of N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl carbamate analogs as sigma2 receptor ligands.
    Vangveravong S, Xu J, Zeng C, Mach RH.
    Bioorg Med Chem; 2006 Oct 15; 14(20):6988-97. PubMed ID: 16837201
    [Abstract] [Full Text] [Related]

  • 14. 4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity.
    Berardi F, Ferorelli S, Abate C, Colabufo NA, Contino M, Perrone R, Tortorella V.
    J Med Chem; 2004 Apr 22; 47(9):2308-17. PubMed ID: 15084129
    [Abstract] [Full Text] [Related]

  • 15. Sigma-1 ligands: Tic-hydantoin as a key pharmacophore.
    Toussaint M, Mousset D, Foulon C, Jacquemard U, Vaccher C, Melnyk P.
    Eur J Med Chem; 2010 Jan 22; 45(1):256-63. PubMed ID: 19875205
    [Abstract] [Full Text] [Related]

  • 16. Exploration of ring size in a series of cyclic vicinal diamines with σ₁ receptor affinity.
    Moussa IA, Banister SD, Manoli M, Doddareddy MR, Cui J, Mach RH, Kassiou M.
    Bioorg Med Chem Lett; 2012 Sep 01; 22(17):5493-7. PubMed ID: 22850210
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and pharmacological evaluation of Tic-hydantoin derivatives as selective sigma1 ligands. Part 2.
    Cazenave Gassiot A, Charton J, Girault-Mizzi S, Gilleron P, Debreu-Fontaine MA, Sergheraert C, Melnyk P.
    Bioorg Med Chem Lett; 2005 Nov 01; 15(21):4828-32. PubMed ID: 16140009
    [Abstract] [Full Text] [Related]

  • 18. Synthesis of novel sigma-receptor ligands from methyl alpha-D-mannopyranoside.
    Wiedemeyer K, Wünsch B.
    Carbohydr Res; 2006 Oct 16; 341(14):2321-34. PubMed ID: 16854396
    [Abstract] [Full Text] [Related]

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  • 20. Novel sigma receptor ligands: synthesis and biological profile.
    Prezzavento O, Campisi A, Ronsisvalle S, Li Volti G, Marrazzo A, Bramanti V, Cannavò G, Vanella L, Cagnotto A, Mennini T, Ientile R, Ronsisvalle G.
    J Med Chem; 2007 Mar 08; 50(5):951-61. PubMed ID: 17328523
    [Abstract] [Full Text] [Related]

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