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Journal Abstract Search

361 related items for PubMed ID: 15082748

  • 1. Preferential inhibition of T helper 1, but not T helper 2, cytokines in vitro by L-826,141 [4-[2-(3,4-Bisdifluromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]3-methylpyridine-1-oxide], a potent and selective phosphodiesterase 4 inhibitor.
    Claveau D, Chen SL, O'Keefe S, Zaller DM, Styhler A, Liu S, Huang Z, Nicholson DW, Mancini JA.
    J Pharmacol Exp Ther; 2004 Aug; 310(2):752-60. PubMed ID: 15082748
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  • 3. Differential regulation of human antigen-specific Th1 and Th2 lymphocyte responses by isozyme selective cyclic nucleotide phosphodiesterase inhibitors.
    Essayan DM, Kagey-Sobotka A, Lichtenstein LM, Huang SK.
    J Pharmacol Exp Ther; 1997 Jul; 282(1):505-12. PubMed ID: 9223593
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  • 4. Peripheral phosphodiesterase 4 inhibition produced by 4-[2-(3,4-Bis-difluoromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]-3-methylpyridine-1-oxide (L-826,141) prevents experimental autoimmune encephalomyelitis.
    Moore CS, Earl N, Frenette R, Styhler A, Mancini JA, Nicholson DW, Hebb AL, Owens T, Robertson GS.
    J Pharmacol Exp Ther; 2006 Oct; 319(1):63-72. PubMed ID: 16809479
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  • 6. Effects of ciclamilast, a new PDE 4 PDE4 inhibitor, on airway hyperresponsiveness, PDE4D expression and airway inflammation in a murine model of asthma.
    Deng YM, Xie QM, Tang HF, Sun JG, Deng JF, Chen JQ, Yang SY.
    Eur J Pharmacol; 2006 Oct 10; 547(1-3):125-35. PubMed ID: 16956605
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  • 7. Anti-inflammatory potential of the selective phosphodiesterase 4 inhibitor N-(3,5-dichloro-pyrid-4-yl)-[1-(4-fluorobenzyl)-5-hydroxy-indole-3-yl]-glyoxylic acid amide (AWD 12-281), in human cell preparations.
    Draheim R, Egerland U, Rundfeldt C.
    J Pharmacol Exp Ther; 2004 Feb 10; 308(2):555-63. PubMed ID: 14610230
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  • 9. Amelioration of collagen-induced arthritis in mice by a novel phosphodiesterase 7 and 4 dual inhibitor, YM-393059.
    Yamamoto S, Sugahara S, Ikeda K, Shimizu Y.
    Eur J Pharmacol; 2007 Mar 22; 559(2-3):219-26. PubMed ID: 17250824
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  • 10. Effects of the phosphodiesterase IV inhibitor rolipram on Th1 and Th2 immune responses in mice.
    Yamaki K, Li X, Uchida H, Alam AH, Hossain MA, Yanagisawa R, Takano H, Taneda S, Hayashi H, Mori Y, Yoshino S.
    J Pharm Pharmacol; 2004 Jul 22; 56(7):877-82. PubMed ID: 15233866
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  • 12. Differential effects of lead and cAMP on development and activities of Th1- and Th2-lymphocytes.
    Heo Y, Lee WT, Lawrence DA.
    Toxicol Sci; 1998 Jun 22; 43(2):172-85. PubMed ID: 9710959
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  • 14. Effect of rolipram, a phosphodiesterase IV inhibitor, on allergic footpad swelling using various adjuvants in mice.
    Yamaki K, Alam AH, Hossain MA, Taneda S, Yanagisawa R, Takano H, Yoshino S.
    Scand J Immunol; 2005 Oct 22; 62(4):378-84. PubMed ID: 16253125
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  • 18. Difference in preventive effects between the phosphodiesterase iv inhibitor rolipram and anti-arthritic drugs on antigen-induced arthritis in mice.
    Yamaki K, Li X, Hossain MA, Alam AH, Taneda S, Yanagisawa R, Takano H, Yoshino S.
    Immunol Invest; 2007 Oct 22; 36(2):131-45. PubMed ID: 17365015
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  • 19. Pharmacological profile of a novel phosphodiesterase 7A and -4 dual inhibitor, YM-393059, on acute and chronic inflammation models.
    Yamamoto S, Sugahara S, Ikeda K, Shimizu Y.
    Eur J Pharmacol; 2006 Nov 21; 550(1-3):166-72. PubMed ID: 17010967
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