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Journal Abstract Search

298 related items for PubMed ID: 15100318

  • 21. Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1-antitrypsin deficiency.
    Ordóñez A, Snapp EL, Tan L, Miranda E, Marciniak SJ, Lomas DA.
    Hepatology; 2013 May; 57(5):2049-60. PubMed ID: 23197448
    [Abstract] [Full Text] [Related]

  • 22. Quantitation of circulating wild-type alpha-1-antitrypsin in heterozygous carriers of the S and Z deficiency alleles.
    Donato LJ, Karras RM, Katzmann JA, Murray DL, Snyder MR.
    Respir Res; 2015 Aug 05; 16(1):96. PubMed ID: 26243289
    [Abstract] [Full Text] [Related]

  • 23. Multiple Genes Core to ERAD, Macroautophagy and Lysosomal Degradation Pathways Participate in the Proteostasis Response in α1-Antitrypsin Deficiency.
    Li J, Moretti F, Hidvegi T, Sviben S, Fitzpatrick JAJ, Sundaramoorthi H, Pak SC, Silverman GA, Knapp B, Filipuzzi I, Alford J, Reece-Hoyes J, Nigsch F, Murphy LO, Nyfeler B, Perlmutter DH.
    Cell Mol Gastroenterol Hepatol; 2024 Aug 05; 17(6):1007-1024. PubMed ID: 38336172
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  • 25. Protein Misfolding and Aggregation: The Relatedness between Parkinson's Disease and Hepatic Endoplasmic Reticulum Storage Disorders.
    Padilla-Godínez FJ, Ramos-Acevedo R, Martínez-Becerril HA, Bernal-Conde LD, Garrido-Figueroa JF, Hiriart M, Hernández-López A, Argüero-Sánchez R, Callea F, Guerra-Crespo M.
    Int J Mol Sci; 2021 Nov 18; 22(22):. PubMed ID: 34830348
    [Abstract] [Full Text] [Related]

  • 26. Endoplasmic Reticulum Stress Response and Mutant Protein Degradation in CHO Cells Accumulating Antithrombin (C95R) in Russell Bodies.
    Kimura K, Inoue K, Okubo J, Ueda Y, Kawaguchi K, Sakurai H, Wada I, Morita M, Imanaka T.
    Biol Pharm Bull; 2015 Nov 18; 38(12):1980-4. PubMed ID: 26447095
    [Abstract] [Full Text] [Related]

  • 27. Rapamycin reduces intrahepatic alpha-1-antitrypsin mutant Z protein polymers and liver injury in a mouse model.
    Kaushal S, Annamali M, Blomenkamp K, Rudnick D, Halloran D, Brunt EM, Teckman JH.
    Exp Biol Med (Maywood); 2010 Jun 18; 235(6):700-9. PubMed ID: 20511674
    [Abstract] [Full Text] [Related]

  • 28. Changes of endoplasmic reticulum chaperone complexes, redox state, and impaired protein disulfide reductase activity in misfolding alpha1-antitrypsin transgenic mice.
    Papp E, Száraz P, Korcsmáros T, Csermely P.
    FASEB J; 2006 May 18; 20(7):1018-20. PubMed ID: 16571774
    [Abstract] [Full Text] [Related]

  • 29. HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease.
    Wei J, Harada BT, Lu D, Ma R, Gao B, Xu Y, Montauti E, Mani N, Chaudhuri SM, Gregory S, Weinberg SE, Zhang DD, Green R, He C, Fang D.
    Mol Cell; 2021 Dec 16; 81(24):5052-5065.e6. PubMed ID: 34847358
    [Abstract] [Full Text] [Related]

  • 30. Therapeutic targeting of misfolding and conformational change in α1-antitrypsin deficiency.
    Nyon MP, Gooptu B.
    Future Med Chem; 2014 Jun 16; 6(9):1047-65. PubMed ID: 25068987
    [Abstract] [Full Text] [Related]

  • 31. Function of monocytes and monocyte-derived macrophages in α1-antitrypsin deficiency.
    Van't Wout EF, van Schadewijk A, Lomas DA, Stolk J, Marciniak SJ, Hiemstra PS.
    Eur Respir J; 2015 Feb 16; 45(2):365-76. PubMed ID: 25323228
    [Abstract] [Full Text] [Related]

  • 32. Evidence for unfolded protein response activation in monocytes from individuals with alpha-1 antitrypsin deficiency.
    Carroll TP, Greene CM, O'Connor CA, Nolan AM, O'Neill SJ, McElvaney NG.
    J Immunol; 2010 Apr 15; 184(8):4538-46. PubMed ID: 20228200
    [Abstract] [Full Text] [Related]

  • 33. Molecular basis of α1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer.
    Yamasaki M, Sendall TJ, Pearce MC, Whisstock JC, Huntington JA.
    EMBO Rep; 2011 Sep 30; 12(10):1011-7. PubMed ID: 21909074
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  • 35. Retarded protein folding of the human Z-type α₁-antitrypsin variant is suppressed by Cpr2p.
    Jung CH, Kim YH, Lee K, Im H.
    Biochem Biophys Res Commun; 2014 Feb 28; 445(1):191-5. PubMed ID: 24502947
    [Abstract] [Full Text] [Related]

  • 36. Familial prion protein mutants inhibit Hrd1-mediated retrotranslocation of misfolded proteins by depleting misfolded protein sensor BiP.
    Peters SL, Déry MA, LeBlanc AC.
    Hum Mol Genet; 2016 Mar 01; 25(5):976-88. PubMed ID: 26740554
    [Abstract] [Full Text] [Related]

  • 37. BiP expression is not increased by the accumulation of PiZ alpha 1-antitrypsin in the endoplasmic reticulum.
    Cresteil D, Ciccarelli E, Soni T, Alonso MA, Jacobs P, Bollen A, Alvarez F.
    FEBS Lett; 1990 Jul 16; 267(2):277-80. PubMed ID: 2379586
    [Abstract] [Full Text] [Related]

  • 38. Alpha1-antitrypsin deficiency: liver disease associated with retention of a mutant secretory glycoprotein in the endoplasmic reticulum.
    Perlmutter DH.
    Methods Mol Biol; 2003 Jul 16; 232():39-56. PubMed ID: 12840538
    [No Abstract] [Full Text] [Related]

  • 39. Z α1-antitrypsin confers a proinflammatory phenotype that contributes to chronic obstructive pulmonary disease.
    Alam S, Li Z, Atkinson C, Jonigk D, Janciauskiene S, Mahadeva R.
    Am J Respir Crit Care Med; 2014 Apr 15; 189(8):909-31. PubMed ID: 24592811
    [Abstract] [Full Text] [Related]

  • 40. A lag in intracellular degradation of mutant alpha 1-antitrypsin correlates with the liver disease phenotype in homozygous PiZZ alpha 1-antitrypsin deficiency.
    Wu Y, Whitman I, Molmenti E, Moore K, Hippenmeyer P, Perlmutter DH.
    Proc Natl Acad Sci U S A; 1994 Sep 13; 91(19):9014-8. PubMed ID: 8090762
    [Abstract] [Full Text] [Related]

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