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Journal Abstract Search

244 related items for PubMed ID: 15102439

  • 1. Tuberous sclerosis complex: from Drosophila to human disease.
    Pan D, Dong J, Zhang Y, Gao X.
    Trends Cell Biol; 2004 Feb; 14(2):78-85. PubMed ID: 15102439
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  • 2. Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins.
    Zhang Y, Gao X, Saucedo LJ, Ru B, Edgar BA, Pan D.
    Nat Cell Biol; 2003 Jun; 5(6):578-81. PubMed ID: 12771962
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  • 4. Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb.
    Tee AR, Manning BD, Roux PP, Cantley LC, Blenis J.
    Curr Biol; 2003 Aug 05; 13(15):1259-68. PubMed ID: 12906785
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  • 5. Non-canonical functions of the tuberous sclerosis complex-Rheb signalling axis.
    Neuman NA, Henske EP.
    EMBO Mol Med; 2011 Apr 05; 3(4):189-200. PubMed ID: 21412983
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  • 6. Rhebbing up mTOR: new insights on TSC1 and TSC2, and the pathogenesis of tuberous sclerosis.
    Kwiatkowski DJ.
    Cancer Biol Ther; 2003 Apr 05; 2(5):471-6. PubMed ID: 14614311
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  • 7. Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis.
    Zech R, Kiontke S, Mueller U, Oeckinghaus A, Kümmel D.
    J Biol Chem; 2016 Sep 16; 291(38):20008-20. PubMed ID: 27493206
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  • 8. TSC1/TSC2 and Rheb have different effects on TORC1 and TORC2 activity.
    Yang Q, Inoki K, Kim E, Guan KL.
    Proc Natl Acad Sci U S A; 2006 May 02; 103(18):6811-6. PubMed ID: 16627617
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  • 11. Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2.
    Garami A, Zwartkruis FJ, Nobukuni T, Joaquin M, Roccio M, Stocker H, Kozma SC, Hafen E, Bos JL, Thomas G.
    Mol Cell; 2003 Jun 02; 11(6):1457-66. PubMed ID: 12820960
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  • 14. Rheb fills a GAP between TSC and TOR.
    Manning BD, Cantley LC.
    Trends Biochem Sci; 2003 Nov 02; 28(11):573-6. PubMed ID: 14607085
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  • 15. The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis.
    Kang YJ, Lu MK, Guan KL.
    Cell Death Differ; 2011 Jan 02; 18(1):133-44. PubMed ID: 20616807
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  • 16. Structural basis for the unique biological function of small GTPase RHEB.
    Yu Y, Li S, Xu X, Li Y, Guan K, Arnold E, Ding J.
    J Biol Chem; 2005 Apr 29; 280(17):17093-100. PubMed ID: 15728574
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  • 17. Activation of Rheb, but not of mTORC1, impairs spine synapse morphogenesis in tuberous sclerosis complex.
    Yasuda S, Sugiura H, Katsurabayashi S, Shimada T, Tanaka H, Takasaki K, Iwasaki K, Kobayashi T, Hino O, Yamagata K.
    Sci Rep; 2014 Jun 03; 4():5155. PubMed ID: 24889507
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  • 18. Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.
    Inoki K, Li Y, Xu T, Guan KL.
    Genes Dev; 2003 Aug 01; 17(15):1829-34. PubMed ID: 12869586
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  • 19. The TSC1-TSC2 complex: a molecular switchboard controlling cell growth.
    Huang J, Manning BD.
    Biochem J; 2008 Jun 01; 412(2):179-90. PubMed ID: 18466115
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  • 20. Farnesyltransferase inhibitors reverse altered growth and distribution of actin filaments in Tsc-deficient cells via inhibition of both rapamycin-sensitive and -insensitive pathways.
    Gau CL, Kato-Stankiewicz J, Jiang C, Miyamoto S, Guo L, Tamanoi F.
    Mol Cancer Ther; 2005 Jun 01; 4(6):918-26. PubMed ID: 15956249
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