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Journal Abstract Search

217 related items for PubMed ID: 15102944

  • 1. Activators of the rat pregnane X receptor differentially modulate hepatic and intestinal gene expression.
    Hartley DP, Dai X, He YD, Carlini EJ, Wang B, Huskey SE, Ulrich RG, Rushmore TH, Evers R, Evans DC.
    Mol Pharmacol; 2004 May; 65(5):1159-71. PubMed ID: 15102944
    [Abstract] [Full Text] [Related]

  • 2. Microarray-based compendium of hepatic gene expression profiles for prototypical ADME gene-inducing compounds in rats and mice in vivo.
    Slatter JG, Cheng O, Cornwell PD, de Souza A, Rockett J, Rushmore T, Hartley D, Evers R, He Y, Dai X, Hu R, Caguyong M, Roberts CJ, Castle J, Ulrich RG.
    Xenobiotica; 2006 May; 36(10-11):902-37. PubMed ID: 17118914
    [Abstract] [Full Text] [Related]

  • 3. Lipopolysaccharide and cecal ligation/puncture differentially affect the subcellular distribution of the pregnane X receptor but consistently cause suppression of its target genes CYP3A.
    Sachdeva K, Yan B, Chichester CO.
    Shock; 2003 May; 19(5):469-74. PubMed ID: 12744492
    [Abstract] [Full Text] [Related]

  • 4. o,p'-DDT elicits PXR/CAR-, not ER-, mediated responses in the immature ovariectomized rat liver.
    Kiyosawa N, Kwekel JC, Burgoon LD, Williams KJ, Tashiro C, Chittim B, Zacharewski TR.
    Toxicol Sci; 2008 Feb; 101(2):350-63. PubMed ID: 17984292
    [Abstract] [Full Text] [Related]

  • 5. Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression.
    Roth A, Looser R, Kaufmann M, Blättler SM, Rencurel F, Huang W, Moore DD, Meyer UA.
    Mol Pharmacol; 2008 Apr; 73(4):1282-9. PubMed ID: 18187584
    [Abstract] [Full Text] [Related]

  • 6. Effect of prototypical inducing agents on P-glycoprotein and CYP3A expression in mouse tissues.
    Matheny CJ, Ali RY, Yang X, Pollack GM.
    Drug Metab Dispos; 2004 Sep; 32(9):1008-14. PubMed ID: 15319343
    [Abstract] [Full Text] [Related]

  • 7. The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism.
    Roques BB, Leghait J, Lacroix MZ, Lasserre F, Pineau T, Viguié C, Martin PG.
    Biochem Pharmacol; 2013 Oct 01; 86(7):997-1039. PubMed ID: 23962444
    [Abstract] [Full Text] [Related]

  • 8. The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor.
    Wyde ME, Bartolucci E, Ueda A, Zhang H, Yan B, Negishi M, You L.
    Mol Pharmacol; 2003 Aug 01; 64(2):474-81. PubMed ID: 12869653
    [Abstract] [Full Text] [Related]

  • 9. Di-n-butyl phthalate activates constitutive androstane receptor and pregnane X receptor and enhances the expression of steroid-metabolizing enzymes in the liver of rat fetuses.
    Wyde ME, Kirwan SE, Zhang F, Laughter A, Hoffman HB, Bartolucci-Page E, Gaido KW, Yan B, You L.
    Toxicol Sci; 2005 Aug 01; 86(2):281-90. PubMed ID: 15901914
    [Abstract] [Full Text] [Related]

  • 10. Regulation of the rat glutathione S-transferase A2 gene by glucocorticoids: involvement of both the glucocorticoid and pregnane X receptors.
    Falkner KC, Pinaire JA, Xiao GH, Geoghegan TE, Prough RA.
    Mol Pharmacol; 2001 Sep 01; 60(3):611-9. PubMed ID: 11502894
    [Abstract] [Full Text] [Related]

  • 11. Effects of dexamethasone on mRNA abundance of nuclear receptors and hepatic nuclear receptor target genes in neonatal calves.
    Greger DL, Blum JW.
    J Anim Physiol Anim Nutr (Berl); 2007 Feb 01; 91(1-2):62-7. PubMed ID: 17217392
    [Abstract] [Full Text] [Related]

  • 12. Comparison of effects of VDR versus PXR, FXR and GR ligands on the regulation of CYP3A isozymes in rat and human intestine and liver.
    Khan AA, Chow EC, van Loenen-Weemaes AM, Porte RJ, Pang KS, Groothuis GM.
    Eur J Pharm Sci; 2009 May 12; 37(2):115-25. PubMed ID: 19429418
    [Abstract] [Full Text] [Related]

  • 13. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
    Wagner M, Halilbasic E, Marschall HU, Zollner G, Fickert P, Langner C, Zatloukal K, Denk H, Trauner M.
    Hepatology; 2005 Aug 12; 42(2):420-30. PubMed ID: 15986414
    [Abstract] [Full Text] [Related]

  • 14. The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice.
    Teng S, Piquette-Miller M.
    J Pharmacol Exp Ther; 2005 Feb 12; 312(2):841-8. PubMed ID: 15456840
    [Abstract] [Full Text] [Related]

  • 15. Gene regulation for the senescence marker protein DHEA-sulfotransferase by the xenobiotic-activated nuclear pregnane X receptor (PXR).
    Echchgadda I, Song CS, Oh TS, Cho SH, Rivera OJ, Chatterjee B.
    Mech Ageing Dev; 2004 Feb 12; 125(10-11):733-45. PubMed ID: 15541768
    [Abstract] [Full Text] [Related]

  • 16. Chronic ethanol exposure downregulates hepatic expression of pregnane X receptor and P450 3A11 in female ICR mice.
    Wang JP, Xu DX, Sun MF, Chen YH, Wang H, Wei W.
    Toxicology; 2005 Nov 15; 215(3):234-44. PubMed ID: 16126318
    [Abstract] [Full Text] [Related]

  • 17. Identification of potential pharmacological and toxicological targets differentiating structural analogs by a combination of transcriptional profiling and promoter analysis in LS-180 and Caco-2 adenocarcinoma cell lines.
    Hartley DP, Dai X, Yabut J, Chu X, Cheng O, Zhang T, He YD, Roberts C, Ulrich R, Evers R, Evans DC.
    Pharmacogenet Genomics; 2006 Aug 15; 16(8):579-99. PubMed ID: 16847427
    [Abstract] [Full Text] [Related]

  • 18. Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver.
    Xu DX, Wei W, Sun MF, Wu CY, Wang JP, Wei LZ, Zhou CF.
    Free Radic Biol Med; 2004 Jul 01; 37(1):10-22. PubMed ID: 15183191
    [Abstract] [Full Text] [Related]

  • 19. Gender dictates the nuclear receptor-mediated regulation of CYP3A44.
    Anakk S, Huang W, Staudinger JL, Tan K, Cole TJ, Moore DD, Strobel HW.
    Drug Metab Dispos; 2007 Jan 01; 35(1):36-42. PubMed ID: 17020958
    [Abstract] [Full Text] [Related]

  • 20. Repression of PXR-mediated induction of hepatic CYP3A gene expression by protein kinase C.
    Ding X, Staudinger JL.
    Biochem Pharmacol; 2005 Mar 01; 69(5):867-73. PubMed ID: 15710363
    [Abstract] [Full Text] [Related]

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