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Journal Abstract Search


191 related items for PubMed ID: 15109656

  • 1. Synthesis of 1alpha,25-dihydroxyvitamin D3-26,23-lactams (DLAMs), a novel series of 1 alpha,25-dihydroxyvitamin D3 antagonist.
    Kato Y, Nakano Y, Sano H, Tanatani A, Kobayashi H, Shimazawa R, Koshino H, Hashimoto Y, Nagasawa K.
    Bioorg Med Chem Lett; 2004 May 17; 14(10):2579-83. PubMed ID: 15109656
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  • 3. Structure-activity relationship studies on vitamin D lactam derivatives as vitamin D receptor antagonist.
    Cho K, Uneuchi F, Kato-Nakamura Y, Namekawa J, Ishizuka S, Takenouchi K, Nagasawa K.
    Bioorg Med Chem Lett; 2008 Aug 01; 18(15):4287-90. PubMed ID: 18635349
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  • 4. Novel vitamin D3 analogs, 1alpha, 25(OH)2D(3)-26, 23-lactam (DLAMs), antagonize bone resorption via suppressing RANKL expression in osteoblasts.
    Inada M, Tsukamoto K, Hirata M, Takita M, Nagasawa K, Miyaura C.
    Biochem Biophys Res Commun; 2008 Aug 01; 372(3):434-9. PubMed ID: 18489902
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  • 5. 1alpha,25-Dihydroxyvitamin D(3)-26,23-lactam analogues function as vitamin D receptor antagonists in human and rodent cells.
    Ishizuka S, Kurihara N, Hiruma Y, Miura D, Namekawa J, Tamura A, Kato-Nakamura Y, Nakano Y, Takenouchi K, Hashimoto Y, Nagasawa K, Roodman GD.
    J Steroid Biochem Mol Biol; 2008 Jun 01; 110(3-5):269-77. PubMed ID: 18501591
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  • 8. Synthetic studies of (23S,25R)-1α,25-dihydroxyvitamin D3 26,23-lactone (calcitriol lactone) and its derivatives.
    Akagi Y, Nagata A, Odagi M, Nagasawa K.
    J Steroid Biochem Mol Biol; 2018 Mar 01; 177():240-246. PubMed ID: 28757443
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  • 9. Synthesis and structure-activity relationships of 16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs having side chains of different sizes.
    Takaku H, Miyamoto Y, Asami S, Shimazaki M, Yamada S, Yamamoto K, Udagawa N, DeLuca HF, Shimizu M.
    Bioorg Med Chem; 2008 Feb 15; 16(4):1796-815. PubMed ID: 18032055
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  • 10. Effect of 25-hydroxyl group orientation on biological activity and binding to the 1alpha,25-dihydroxy vitamin D3 receptor.
    Collins ED, Bishop JE, Bula CM, Acevedo A, Okamura WH, Norman AW.
    J Steroid Biochem Mol Biol; 2005 Mar 15; 94(4):279-88. PubMed ID: 15857747
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  • 11. Design, synthesis, and biological studies of the A-ring-modified 1,25-dihydroxyvitamin D3 analogs.
    Takayama H, Kittaka A, Fujishima T, Suhara Y.
    Recent Results Cancer Res; 2003 Mar 15; 164():289-317. PubMed ID: 12899530
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  • 12. Novel 1alpha,25-dihydroxyvitamin D3 analogues with the side chain at C12.
    González-Avión XC, Mouriño A, Rochel N, Moras D.
    J Med Chem; 2006 Mar 09; 49(5):1509-16. PubMed ID: 16509569
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  • 13. Synthesis and biological activities of new 1alpha,25-dihydroxy-19-norvitamin D3 analogs with modifications in both the A-ring and the side chain.
    Shimizu M, Miyamoto Y, Kobayashi E, Shimazaki M, Yamamoto K, Reischl W, Yamada S.
    Bioorg Med Chem; 2006 Jun 15; 14(12):4277-94. PubMed ID: 16503143
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  • 14. Novel 2-alkyl-1alpha,25-dihydroxy-19-norvitamin D3: efficient synthesis with Julia olefination, evaluation of biological activity and development of new analyzing system for co-activator recruitment.
    Arai MA, Kittaka A.
    Anticancer Res; 2006 Jun 15; 26(4A):2621-31. PubMed ID: 16886672
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  • 15. 2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure.
    Shimizu M, Miyamoto Y, Takaku H, Matsuo M, Nakabayashi M, Masuno H, Udagawa N, DeLuca HF, Ikura T, Ito N.
    Bioorg Med Chem; 2008 Jul 15; 16(14):6949-64. PubMed ID: 18539034
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  • 16. 2,2-Functionalized analogues of 1alpha,25-dihydroxyvitamin D3, the potent inducers of cell differentiation.
    Fujishima T, Kittaka A, Kurihara M, Saito N, Honzawa S, Kishimoto S, Sugiura T, Waku K, Takayama H.
    J Steroid Biochem Mol Biol; 2004 May 15; 89-90(1-5):89-92. PubMed ID: 15225752
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  • 17. Regulation of the vitamin D receptor by vitamin D lactam derivatives.
    Asano L, Waku T, Abe R, Kuwabara N, Ito I, Yanagisawa J, Nagasawa K, Shimizu T.
    FEBS Lett; 2016 Sep 15; 590(18):3270-9. PubMed ID: 27500498
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  • 18. Differential biological effects of 1,25-dihydroxyVitamin D3 on melanoma cell lines in vitro.
    Seifert M, Rech M, Meineke V, Tilgen W, Reichrath J.
    J Steroid Biochem Mol Biol; 2004 May 15; 89-90(1-5):375-9. PubMed ID: 15225804
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  • 19. 13-Methyl-substituted des-C,D analogs of (20S)-1alpha,25-dihydroxy-2-methylene-19-norvitamin D3 (2MD): synthesis and biological evaluation.
    Plonska-Ocypa K, Sicinski RR, Plum LA, Grzywacz P, Frelek J, Clagett-Dame M, DeLuca HF.
    Bioorg Med Chem; 2009 Feb 15; 17(4):1747-63. PubMed ID: 19167893
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  • 20. 1alpha,25-dihydroxyvitamin D(3)-26,23-lactone analogs antagonize differentiation of human leukemia cells (HL-60 cells) but not of human acute promyelocytic leukemia cells (NB4 cells).
    Miura D, Manabe K, Gao Q, Norman AW, Ishizuka S.
    FEBS Lett; 1999 Oct 29; 460(2):297-302. PubMed ID: 10544253
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