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PUBMED FOR HANDHELDS

Journal Abstract Search


348 related items for PubMed ID: 15115402

  • 21. Cdc7 kinase inhibitors: 5-heteroaryl-3-carboxamido-2-aryl pyrroles as potential antitumor agents. 1. Lead finding.
    Menichincheri M, Albanese C, Alli C, Ballinari D, Bargiotti A, Caldarelli M, Ciavolella A, Cirla A, Colombo M, Colotta F, Croci V, D'Alessio R, D'Anello M, Ermoli A, Fiorentini F, Forte B, Galvani A, Giordano P, Isacchi A, Martina K, Molinari A, Moll JK, Montagnoli A, Orsini P, Orzi F, Pesenti E, Pillan A, Roletto F, Scolaro A, Tatò M, Tibolla M, Valsasina B, Varasi M, Vianello P, Volpi D, Santocanale C, Vanotti E.
    J Med Chem; 2010 Oct 28; 53(20):7296-315. PubMed ID: 20873740
    [Abstract] [Full Text] [Related]

  • 22. Potent antitumor activity of MS-247, a novel DNA minor groove binder, evaluated by an in vitro and in vivo human cancer cell line panel.
    Yamori T, Matsunaga A, Sato S, Yamazaki K, Komi A, Ishizu K, Mita I, Edatsugi H, Matsuba Y, Takezawa K, Nakanishi O, Kohno H, Nakajima Y, Komatsu H, Andoh T, Tsuruo T.
    Cancer Res; 1999 Aug 15; 59(16):4042-9. PubMed ID: 10463605
    [Abstract] [Full Text] [Related]

  • 23. Development of distamycin-related DNA binding anticancer drugs.
    Marchini S, Broggini M, Sessa C, D'Incalci M.
    Expert Opin Investig Drugs; 2001 Sep 15; 10(9):1703-14. PubMed ID: 11772279
    [Abstract] [Full Text] [Related]

  • 24. Combination of thiol antioxidant Silibinin with Brostallicin is associated with increase in the anti-apoptotic protein Bcl-2 and decrease in caspase 3 activity.
    Pook SH, Toh CK, Mahendran R.
    Cancer Lett; 2006 Jul 08; 238(1):146-52. PubMed ID: 16111802
    [Abstract] [Full Text] [Related]

  • 25. Design, synthesis and biological evaluation of new oligopyrrole carboxamides linked with tricyclic DNA-intercalators as potential DNA ligands or topoisomerase inhibitors.
    David-Cordonnier MH, Hildebrand MP, Baldeyrou B, Lansiaux A, Keuser C, Benzschawel K, Lemster T, Pindur U.
    Eur J Med Chem; 2007 Jun 08; 42(6):752-71. PubMed ID: 17433851
    [Abstract] [Full Text] [Related]

  • 26. A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties.
    Kupchinsky S, Centioni S, Howard T, Trzupek J, Roller S, Carnahan V, Townes H, Purnell B, Price C, Handl H, Summerville K, Johnson K, Toth J, Hudson S, Kiakos K, Hartley JA, Lee M.
    Bioorg Med Chem; 2004 Dec 01; 12(23):6221-36. PubMed ID: 15519165
    [Abstract] [Full Text] [Related]

  • 27. Amine-guanidine switch: a promising approach to improve DNA binding and antiproliferative activities.
    Ohara K, Smietana M, Restouin A, Mollard S, Borg JP, Collette Y, Vasseur JJ.
    J Med Chem; 2007 Dec 27; 50(26):6465-75. PubMed ID: 18052116
    [Abstract] [Full Text] [Related]

  • 28. Design, synthesis, DNA binding, and biological evaluation of water-soluble hybrid molecules containing two pyrazole analogues of the alkylating cyclopropylpyrroloindole (CPI) subunit of the antitumor agent CC-1065 and polypyrrole minor groove binders.
    Baraldi PG, Balboni G, Pavani MG, Spalluto G, Tabrizi MA, Clercq ED, Balzarini J, Bando T, Sugiyama H, Romagnoli R.
    J Med Chem; 2001 Aug 02; 44(16):2536-43. PubMed ID: 11472207
    [Abstract] [Full Text] [Related]

  • 29. Oligopyrrole carboxamides linked with a nucleobase as potential DNA minor groove binding ligands: synthesis, DNA binding and biological evaluation.
    Keuser C, Pindur U.
    Pharmazie; 2006 Apr 02; 61(4):261-8. PubMed ID: 16649534
    [Abstract] [Full Text] [Related]

  • 30. Synthesis and antitumor activity of new benzoheterocyclic derivatives of distamycin A.
    Baraldi PG, Romagnoli R, Beria I, Cozzi P, Geroni C, Mongelli N, Bianchi N, Mischiati C, Gambari R.
    J Med Chem; 2000 Jul 13; 43(14):2675-84. PubMed ID: 10893305
    [Abstract] [Full Text] [Related]

  • 31. Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies.
    Baraldi PG, Beria I, Cozzi P, Geroni C, Espinosa A, Gallo MA, Entrena A, Bingham JP, Hartley JA, Romagnoli R.
    Bioorg Med Chem; 2004 Jul 15; 12(14):3911-21. PubMed ID: 15210158
    [Abstract] [Full Text] [Related]

  • 32.
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  • 33. alpha-halogenoacrylic derivatives of antitumor agents.
    Romagnoli R, Baraldi PG, Cruz-Lopez O, Lopez-Cara C, Preti D.
    Mini Rev Med Chem; 2009 Jan 15; 9(1):81-94. PubMed ID: 19149662
    [Abstract] [Full Text] [Related]

  • 34. Synthesis and biological evaluation of polyenylpyrrole derivatives as anticancer agents acting through caspases-dependent apoptosis.
    Fang Z, Liao PC, Yang YL, Yang FL, Chen YL, Lam Y, Hua KF, Wu SH.
    J Med Chem; 2010 Nov 25; 53(22):7967-78. PubMed ID: 20964408
    [Abstract] [Full Text] [Related]

  • 35.
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  • 36. Cytotoxic alpha-bromoacrylic derivatives of distamycin analogues modified at the amidino moiety.
    Cozzi P, Beria I, Caldarelli M, Geroni C, Mongelli N, Pennella G.
    Bioorg Med Chem Lett; 2000 Jun 05; 10(11):1273-6. PubMed ID: 10866398
    [Abstract] [Full Text] [Related]

  • 37.
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  • 38. [2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1.
    Baraldi PG, Cacciari B, Guiotto A, Romagnoli R, Spalluto G, Leoni A, Bianchi N, Feriotto G, Rutigliano C, Mischiati C, Gambari R.
    Nucleosides Nucleotides Nucleic Acids; 2000 Aug 05; 19(8):1219-29. PubMed ID: 11097052
    [Abstract] [Full Text] [Related]

  • 39.
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  • 40. Novel cyclopropapyrroloindole derivative (AT-3510) bearing methoxycarbonyl and trifluoromethyl groups.
    Fukuda Y, Furuta H, Kusama Y, Ebisu H, Oomori Y, Terashima S.
    J Med Chem; 1999 Apr 22; 42(8):1448-58. PubMed ID: 10212131
    [Abstract] [Full Text] [Related]


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