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121 related items for PubMed ID: 15117960

  • 1. Nerve growth factor promotes the survival of sympathetic neurons through the cooperative function of the protein kinase C and phosphatidylinositol 3-kinase pathways.
    Pierchala BA, Ahrens RC, Paden AJ, Johnson EM.
    J Biol Chem; 2004 Jul 02; 279(27):27986-93. PubMed ID: 15117960
    [Abstract] [Full Text] [Related]

  • 2. Phosphatidylinositol 3-kinase is required for the trophic, but not the survival-promoting, actions of NGF on sympathetic neurons.
    Tsui-Pierchala BA, Putcha GV, Johnson EM.
    J Neurosci; 2000 Oct 01; 20(19):7228-37. PubMed ID: 11007879
    [Abstract] [Full Text] [Related]

  • 3. A retrograde apoptotic signal originating in NGF-deprived distal axons of rat sympathetic neurons in compartmented cultures.
    Mok SA, Lund K, Campenot RB.
    Cell Res; 2009 May 01; 19(5):546-60. PubMed ID: 19188931
    [Abstract] [Full Text] [Related]

  • 4. Divergence in the anti-apoptotic signalling pathways used by nerve growth factor and basic fibroblast growth factor (bFGF) in PC12 cells: rescue by bFGF involves protein kinase C delta.
    Wert MM, Palfrey HC.
    Biochem J; 2000 Nov 15; 352 Pt 1(Pt 1):175-82. PubMed ID: 11062070
    [Abstract] [Full Text] [Related]

  • 5. Analysis of the NF-kappa B and PI 3-kinase/Akt survival pathways in nerve growth factor-dependent neurons.
    Sarmiere PD, Freeman RS.
    Mol Cell Neurosci; 2001 Sep 15; 18(3):320-31. PubMed ID: 11591132
    [Abstract] [Full Text] [Related]

  • 6. Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.
    Eilers A, Whitfield J, Babij C, Rubin LL, Ham J.
    J Neurosci; 1998 Mar 01; 18(5):1713-24. PubMed ID: 9464996
    [Abstract] [Full Text] [Related]

  • 7. Nerve growth factor (NGF) regulates activity of nuclear factor of activated T-cells (NFAT) in neurons via the phosphatidylinositol 3-kinase (PI3K)-Akt-glycogen synthase kinase 3β (GSK3β) pathway.
    Kim MS, Shutov LP, Gnanasekaran A, Lin Z, Rysted JE, Ulrich JD, Usachev YM.
    J Biol Chem; 2014 Nov 07; 289(45):31349-60. PubMed ID: 25231981
    [Abstract] [Full Text] [Related]

  • 8. Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.
    Crowder RJ, Freeman RS.
    J Neurosci; 1998 Apr 15; 18(8):2933-43. PubMed ID: 9526010
    [Abstract] [Full Text] [Related]

  • 9. Direct inhibition of c-Jun N-terminal kinase in sympathetic neurones prevents c-jun promoter activation and NGF withdrawal-induced death.
    Eilers A, Whitfield J, Shah B, Spadoni C, Desmond H, Ham J.
    J Neurochem; 2001 Mar 15; 76(5):1439-54. PubMed ID: 11238729
    [Abstract] [Full Text] [Related]

  • 10. A role for MAPK/ERK in sympathetic neuron survival: protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside.
    Anderson CN, Tolkovsky AM.
    J Neurosci; 1999 Jan 15; 19(2):664-73. PubMed ID: 9880587
    [Abstract] [Full Text] [Related]

  • 11. Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival.
    Vaillant AR, Mazzoni I, Tudan C, Boudreau M, Kaplan DR, Miller FD.
    J Cell Biol; 1999 Sep 06; 146(5):955-66. PubMed ID: 10477751
    [Abstract] [Full Text] [Related]

  • 12. Ras regulates sympathetic neuron survival by suppressing the p53-mediated cell death pathway.
    Mazzoni IE, Saïd FA, Aloyz R, Miller FD, Kaplan D.
    J Neurosci; 1999 Nov 15; 19(22):9716-27. PubMed ID: 10559381
    [Abstract] [Full Text] [Related]

  • 13. Global analysis of gene expression in NGF-deprived sympathetic neurons identifies molecular pathways associated with cell death.
    Kristiansen M, Menghi F, Hughes R, Hubank M, Ham J.
    BMC Genomics; 2011 Nov 08; 12():551. PubMed ID: 22067274
    [Abstract] [Full Text] [Related]

  • 14. Glycogen synthase kinase-3 beta activity is critical for neuronal death caused by inhibiting phosphatidylinositol 3-kinase or Akt but not for death caused by nerve growth factor withdrawal.
    Crowder RJ, Freeman RS.
    J Biol Chem; 2000 Nov 03; 275(44):34266-71. PubMed ID: 10954722
    [Abstract] [Full Text] [Related]

  • 15. Nerve growth factor functions as a chemoattractant for mast cells through both mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling pathways.
    Sawada J, Itakura A, Tanaka A, Furusaka T, Matsuda H.
    Blood; 2000 Mar 15; 95(6):2052-8. PubMed ID: 10706874
    [Abstract] [Full Text] [Related]

  • 16. Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75.
    Culmsee C, Gerling N, Lehmann M, Nikolova-Karakashian M, Prehn JH, Mattson MP, Krieglstein J.
    Neuroscience; 2002 Mar 15; 115(4):1089-108. PubMed ID: 12453482
    [Abstract] [Full Text] [Related]

  • 17. NGF-withdrawal induces apoptosis in pancreatic beta cells in vitro.
    Pierucci D, Cicconi S, Bonini P, Ferrelli F, Pastore D, Matteucci C, Marselli L, Marchetti P, Ris F, Halban P, Oberholzer J, Federici M, Cozzolino F, Lauro R, Borboni P, Marlier LN.
    Diabetologia; 2001 Oct 15; 44(10):1281-95. PubMed ID: 11692177
    [Abstract] [Full Text] [Related]

  • 18. The proapoptotic dp5 gene is a direct target of the MLK-JNK-c-Jun pathway in sympathetic neurons.
    Towers E, Gilley J, Randall R, Hughes R, Kristiansen M, Ham J.
    Nucleic Acids Res; 2009 May 15; 37(9):3044-60. PubMed ID: 19304750
    [Abstract] [Full Text] [Related]

  • 19. Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons.
    Philpott KL, McCarthy MJ, Klippel A, Rubin LL.
    J Cell Biol; 1997 Nov 03; 139(3):809-15. PubMed ID: 9348296
    [Abstract] [Full Text] [Related]

  • 20. The tyrosine phosphatase inhibitor orthovanadate mimics NGF-induced neuroprotective signaling in rat hippocampal neurons.
    Gerling N, Culmsee C, Klumpp S, Krieglstein J.
    Neurochem Int; 2004 Jun 03; 44(7):505-20. PubMed ID: 15209419
    [Abstract] [Full Text] [Related]

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