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Journal Abstract Search


195 related items for PubMed ID: 15120650

  • 1. MDA-7/IL-24 is a unique cytokine--tumor suppressor in the IL-10 family.
    Chada S, Sutton RB, Ekmekcioglu S, Ellerhorst J, Mumm JB, Leitner WW, Yang HY, Sahin AA, Hunt KK, Fuson KL, Poìndexter N, Roth JA, Ramesh R, Grimm EA, Mhashilkar AM.
    Int Immunopharmacol; 2004 May; 4(5):649-67. PubMed ID: 15120650
    [Abstract] [Full Text] [Related]

  • 2. Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism.
    Chada S, Mhashilkar AM, Ramesh R, Mumm JB, Sutton RB, Bocangel D, Zheng M, Grimm EA, Ekmekcioglu S.
    Mol Ther; 2004 Dec; 10(6):1085-95. PubMed ID: 15564140
    [Abstract] [Full Text] [Related]

  • 3. Melanoma differentiation-associated gene-7 (mda-7)/interleukin (IL)-24 induces anticancer immunity in a syngeneic murine model.
    Miyahara R, Banerjee S, Kawano K, Efferson C, Tsuda N, Miyahara Y, Ioannides CG, Chada S, Ramesh R.
    Cancer Gene Ther; 2006 Aug; 13(8):753-61. PubMed ID: 16543916
    [Abstract] [Full Text] [Related]

  • 4. mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: identification of IL-20 receptor-mediated bystander activity against pancreatic cancer.
    Chada S, Bocangel D, Ramesh R, Grimm EA, Mumm JB, Mhashilkar AM, Zheng M.
    Mol Ther; 2005 May; 11(5):724-33. PubMed ID: 15851011
    [Abstract] [Full Text] [Related]

  • 5. Selective induction of cell cycle arrest and apoptosis in human prostate cancer cells through adenoviral transfer of the melanoma differentiation-associated -7 (mda-7)/interleukin-24 (IL-24) gene.
    Saito Y, Miyahara R, Gopalan B, Litvak A, Inoue S, Shanker M, Branch CD, Mhashilkar AM, Roth JA, Chada S, Ramesh R.
    Cancer Gene Ther; 2005 Mar; 12(3):238-47. PubMed ID: 15578066
    [Abstract] [Full Text] [Related]

  • 6. Activation of the Fas-FasL signaling pathway by MDA-7/IL-24 kills human ovarian cancer cells.
    Gopalan B, Litvak A, Sharma S, Mhashilkar AM, Chada S, Ramesh R.
    Cancer Res; 2005 Apr 15; 65(8):3017-24. PubMed ID: 15833826
    [Abstract] [Full Text] [Related]

  • 7. Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells.
    Su Z, Emdad L, Sauane M, Lebedeva IV, Sarkar D, Gupta P, James CD, Randolph A, Valerie K, Walter MR, Dent P, Fisher PB.
    Oncogene; 2005 Nov 17; 24(51):7552-66. PubMed ID: 16044151
    [Abstract] [Full Text] [Related]

  • 8. mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review).
    Lebedeva IV, Emdad L, Su ZZ, Gupta P, Sauane M, Sarkar D, Staudt MR, Liu SJ, Taher MM, Xiao R, Barral P, Lee SG, Wang D, Vozhilla N, Park ES, Chatman L, Boukerche H, Ramesh R, Inoue S, Chada S, Li R, De Pass AL, Mahasreshti PJ, Dmitriev IP, Curiel DT, Yacoub A, Grant S, Dent P, Senzer N, Nemunaitis JJ, Fisher PB.
    Int J Oncol; 2007 Nov 17; 31(5):985-1007. PubMed ID: 17912425
    [Abstract] [Full Text] [Related]

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  • 10. MDA-7/IL-24, a novel tumor suppressor/cytokine is ubiquitinated and regulated by the ubiquitin-proteasome system, and inhibition of MDA-7/IL-24 degradation enhances the antitumor activity.
    Gopalan B, Shanker M, Scott A, Branch CD, Chada S, Ramesh R.
    Cancer Gene Ther; 2008 Jan 17; 15(1):1-8. PubMed ID: 17828282
    [Abstract] [Full Text] [Related]

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  • 12. Bcl-2 and Bcl-x(L) differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24.
    Lebedeva IV, Sarkar D, Su ZZ, Kitada S, Dent P, Stein CA, Reed JC, Fisher PB.
    Oncogene; 2003 Nov 27; 22(54):8758-73. PubMed ID: 14647471
    [Abstract] [Full Text] [Related]

  • 13. Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients.
    Tong AW, Nemunaitis J, Su D, Zhang Y, Cunningham C, Senzer N, Netto G, Rich D, Mhashilkar A, Parker K, Coffee K, Ramesh R, Ekmekcioglu S, Grimm EA, van Wart Hood J, Merritt J, Chada S.
    Mol Ther; 2005 Jan 27; 11(1):160-72. PubMed ID: 15585417
    [Abstract] [Full Text] [Related]

  • 14. Melanoma differentiation-associated gene-7 protein physically associates with the double-stranded RNA-activated protein kinase PKR.
    Pataer A, Vorburger SA, Chada S, Balachandran S, Barber GN, Roth JA, Hunt KK, Swisher SG.
    Mol Ther; 2005 May 27; 11(5):717-23. PubMed ID: 15851010
    [Abstract] [Full Text] [Related]

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  • 16. Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis.
    Lebedeva IV, Su ZZ, Sarkar D, Gopalkrishnan RV, Waxman S, Yacoub A, Dent P, Fisher PB.
    Oncogene; 2005 Jan 20; 24(4):585-96. PubMed ID: 15580305
    [Abstract] [Full Text] [Related]

  • 17. Mechanistic aspects of mda-7/IL-24 cancer cell selectivity analysed via a bacterial fusion protein.
    Sauane M, Gopalkrishnan RV, Choo HT, Gupta P, Lebedeva IV, Yacoub A, Dent P, Fisher PB.
    Oncogene; 2004 Oct 07; 23(46):7679-90. PubMed ID: 15334067
    [Abstract] [Full Text] [Related]

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  • 19. Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species.
    Lebedeva IV, Su ZZ, Sarkar D, Kitada S, Dent P, Waxman S, Reed JC, Fisher PB.
    Cancer Res; 2003 Dec 01; 63(23):8138-44. PubMed ID: 14678967
    [Abstract] [Full Text] [Related]

  • 20. Ionizing radiation enhances therapeutic activity of mda-7/IL-24: overcoming radiation- and mda-7/IL-24-resistance in prostate cancer cells overexpressing the antiapoptotic proteins bcl-xL or bcl-2.
    Su ZZ, Lebedeva IV, Sarkar D, Emdad L, Gupta P, Kitada S, Dent P, Reed JC, Fisher PB.
    Oncogene; 2006 Apr 13; 25(16):2339-48. PubMed ID: 16331261
    [Abstract] [Full Text] [Related]


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