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Journal Abstract Search

145 related items for PubMed ID: 15121764

  • 1. Metabolism of N,N',N"-triethylenethiophosphoramide by CYP2B1 and CYP2B6 results in the inactivation of both isoforms by two distinct mechanisms.
    Harleton E, Webster M, Bumpus NN, Kent UM, Rae JM, Hollenberg PF.
    J Pharmacol Exp Ther; 2004 Sep; 310(3):1011-9. PubMed ID: 15121764
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  • 2. Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by 2-phenyl-2-(1-piperidinyl)propane.
    Chun J, Kent UM, Moss RM, Sayre LM, Hollenberg PF.
    Drug Metab Dispos; 2000 Aug; 28(8):905-11. PubMed ID: 10901699
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  • 3. Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by n-propylxanthate.
    Kent UM, Yanev S, Hollenberg PF.
    Chem Res Toxicol; 1999 Apr; 12(4):317-22. PubMed ID: 10207119
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  • 4. Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine.
    Kent UM, Pascual L, Roof RA, Ballou DP, Hollenberg PF.
    Arch Biochem Biophys; 2004 Mar 15; 423(2):277-87. PubMed ID: 15001392
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  • 6. Inhibition of human CYP2B6 by N,N',N''-triethylenethiophosphoramide is irreversible and mechanism-based.
    Richter T, Schwab M, Eichelbaum M, Zanger UM.
    Biochem Pharmacol; 2005 Feb 01; 69(3):517-24. PubMed ID: 15652242
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  • 7. Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites.
    Kent UM, Mills DE, Rajnarayanan RV, Alworth WL, Hollenberg PF.
    J Pharmacol Exp Ther; 2002 Feb 01; 300(2):549-58. PubMed ID: 11805216
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  • 8. The naturally occurring cytochrome P450 (P450) 2B6 K262R mutant of P450 2B6 exhibits alterations in substrate metabolism and inactivation.
    Bumpus NN, Sridar C, Kent UM, Hollenberg PF.
    Drug Metab Dispos; 2005 Jun 01; 33(6):795-802. PubMed ID: 15769884
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  • 9. Selective mechanism-based inactivation of cytochromes P-450 2B1 and P-450 2B6 by a series of xanthates.
    Yanev S, Kent UM, Pandova B, Hollenberg PF.
    Drug Metab Dispos; 1999 May 01; 27(5):600-4. PubMed ID: 10220489
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  • 10. The mechanism-based inactivation of human cytochrome P450 2B6 by phencyclidine.
    Jushchyshyn MI, Kent UM, Hollenberg PF.
    Drug Metab Dispos; 2003 Jan 01; 31(1):46-52. PubMed ID: 12485952
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  • 13. Metabolic activation of mifepristone [RU486; 17beta-hydroxy-11beta-(4-dimethylaminophenyl)-17alpha-(1-propynyl)-estra-4,9-dien-3-one] by mammalian cytochromes P450 and the mechanism-based inactivation of human CYP2B6.
    Lin HL, Zhang H, Hollenberg PF.
    J Pharmacol Exp Ther; 2009 Apr 01; 329(1):26-37. PubMed ID: 19168709
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  • 14. Inhibition of bupropion metabolism by selegiline: mechanism-based inactivation of human CYP2B6 and characterization of glutathione and peptide adducts.
    Sridar C, Kenaan C, Hollenberg PF.
    Drug Metab Dispos; 2012 Dec 01; 40(12):2256-66. PubMed ID: 22936314
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  • 18. Selective inhibition of CYP2B6-catalyzed bupropion hydroxylation in human liver microsomes in vitro.
    Turpeinen M, Nieminen R, Juntunen T, Taavitsainen P, Raunio H, Pelkonen O.
    Drug Metab Dispos; 2004 Jun 01; 32(6):626-31. PubMed ID: 15155554
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  • 19. Mechanism-based inactivation of cytochrome P450 2B6 by methadone through destruction of prosthetic heme.
    Amunugama HT, Zhang H, Hollenberg PF.
    Drug Metab Dispos; 2012 Sep 01; 40(9):1765-70. PubMed ID: 22685215
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  • 20. Mechanism-based inactivation of cytochrome P450 2B1 by N-benzyl-1-aminobenzotriazole.
    Kent UM, Bend JR, Chamberlin BA, Gage DA, Hollenberg PF.
    Chem Res Toxicol; 1997 May 01; 10(5):600-8. PubMed ID: 9168259
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