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621 related items for PubMed ID: 15122317

  • 21. Aberrant expression and activation of insulin-like growth factor-1 receptor (IGF-1R) are mediated by an induction of IGF-1R promoter activity and stabilization of IGF-1R mRNA and contributes to growth factor independence and increased survival of the pancreatic cancer cell line MIA PaCa-2.
    Nair PN, De Armond DT, Adamo ML, Strodel WE, Freeman JW.
    Oncogene; 2001 Dec 13; 20(57):8203-14. PubMed ID: 11781836
    [Abstract] [Full Text] [Related]

  • 22. In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417.
    Haluska P, Carboni JM, Loegering DA, Lee FY, Wittman M, Saulnier MG, Frennesson DB, Kalli KR, Conover CA, Attar RM, Kaufmann SH, Gottardis M, Erlichman C.
    Cancer Res; 2006 Jan 01; 66(1):362-71. PubMed ID: 16397250
    [Abstract] [Full Text] [Related]

  • 23. Growth-inhibitory effects of human anti-insulin-like growth factor-I receptor antibody (A12) in an orthotopic nude mouse model of anaplastic thyroid carcinoma.
    Wang Z, Chakravarty G, Kim S, Yazici YD, Younes MN, Jasser SA, Santillan AA, Bucana CD, El-Naggar AK, Myers JN.
    Clin Cancer Res; 2006 Aug 01; 12(15):4755-65. PubMed ID: 16899627
    [Abstract] [Full Text] [Related]

  • 24. Inhibition of insulin-like growth factor-I signaling by ethanol in neuronal cells.
    Hallak H, Seiler AE, Green JS, Henderson A, Ross BN, Rubin R.
    Alcohol Clin Exp Res; 2001 Jul 01; 25(7):1058-64. PubMed ID: 11505033
    [Abstract] [Full Text] [Related]

  • 25. Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells.
    Ota H, Tokunaga E, Chang K, Hikasa M, Iijima K, Eto M, Kozaki K, Akishita M, Ouchi Y, Kaneki M.
    Oncogene; 2006 Jan 12; 25(2):176-85. PubMed ID: 16170353
    [Abstract] [Full Text] [Related]

  • 26. Androgen receptor (AR) expression in AR-negative prostate cancer cells results in differential effects of DHT and IGF-I on proliferation and AR activity between localized and metastatic tumors.
    Plymate SR, Tennant MK, Culp SH, Woodke L, Marcelli M, Colman I, Nelson PS, Carroll JM, Roberts CT, Ware JL.
    Prostate; 2004 Nov 01; 61(3):276-90. PubMed ID: 15368471
    [Abstract] [Full Text] [Related]

  • 27. Recombinant human insulin-like growth factor binding protein 3 inhibits growth of human epidermal growth factor receptor-2-overexpressing breast tumors and potentiates herceptin activity in vivo.
    Jerome L, Alami N, Belanger S, Page V, Yu Q, Paterson J, Shiry L, Pegram M, Leyland-Jones B.
    Cancer Res; 2006 Jul 15; 66(14):7245-52. PubMed ID: 16849573
    [Abstract] [Full Text] [Related]

  • 28. Inhibitory effect of antisense oligodeoxynucleotide to p44/p42 MAPK on angiotensin II-induced hypertrophic response in cultured neonatal rat cardiac myocyte.
    Zhang SQ, Ding B, Guo ZG, Li YX.
    Acta Pharmacol Sin; 2004 Jan 15; 25(1):41-6. PubMed ID: 14704121
    [Abstract] [Full Text] [Related]

  • 29. Immunization with murine breast cancer cells treated with antisense oligodeoxynucleotides to type I insulin-like growth factor receptor induced an antitumoral effect mediated by a CD8+ response involving Fas/Fas ligand cytotoxic pathway.
    Schillaci R, Salatino M, Cassataro J, Proietti CJ, Giambartolomei GH, Rivas MA, Carnevale RP, Charreau EH, Elizalde PV.
    J Immunol; 2006 Mar 15; 176(6):3426-37. PubMed ID: 16517711
    [Abstract] [Full Text] [Related]

  • 30. An inhibitory function for JNK in the regulation of IGF-I signaling in breast cancer.
    Mamay CL, Mingo-Sion AM, Wolf DM, Molina MD, Van Den Berg CL.
    Oncogene; 2003 Jan 30; 22(4):602-14. PubMed ID: 12555073
    [Abstract] [Full Text] [Related]

  • 31. Treatment of human breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor inhibits cell growth, suppresses tumorigenesis, alters the metastatic potential, and prolongs survival in vivo.
    Chernicky CL, Yi L, Tan H, Gan SU, Ilan J.
    Cancer Gene Ther; 2000 Mar 30; 7(3):384-95. PubMed ID: 10766344
    [Abstract] [Full Text] [Related]

  • 32. Co-targeting the EGFR and IGF-IR with anti-EGFR monoclonal antibody ICR62 and the IGF-IR tyrosine kinase inhibitor NVP-AEW541 in colorectal cancer cells.
    Cunningham MP, Thomas H, Marks C, Green M, Fan Z, Modjtahedi H.
    Int J Oncol; 2008 Nov 30; 33(5):1107-13. PubMed ID: 18949375
    [Abstract] [Full Text] [Related]

  • 33. Role of estrogen receptor alpha in modulating IGF-I receptor signaling and function in breast cancer.
    Surmacz E, Bartucci M.
    J Exp Clin Cancer Res; 2004 Sep 30; 23(3):385-94. PubMed ID: 15595626
    [Abstract] [Full Text] [Related]

  • 34. IGF-1 activates hEAG K(+) channels through an Akt-dependent signaling pathway in breast cancer cells: role in cell proliferation.
    Borowiec AS, Hague F, Harir N, Guénin S, Guerineau F, Gouilleux F, Roudbaraki M, Lassoued K, Ouadid-Ahidouch H.
    J Cell Physiol; 2007 Sep 30; 212(3):690-701. PubMed ID: 17520698
    [Abstract] [Full Text] [Related]

  • 35. Retinoic acid-induced growth arrest of MCF-7 cells involves the selective regulation of the IRS-1/PI 3-kinase/AKT pathway.
    del Rincón SV, Rousseau C, Samanta R, Miller WH.
    Oncogene; 2003 May 29; 22(22):3353-60. PubMed ID: 12776186
    [Abstract] [Full Text] [Related]

  • 36. Antisense TRPM-2 oligodeoxynucleotides chemosensitize human androgen-independent PC-3 prostate cancer cells both in vitro and in vivo.
    Miyake H, Chi KN, Gleave ME.
    Clin Cancer Res; 2000 May 29; 6(5):1655-63. PubMed ID: 10815883
    [Abstract] [Full Text] [Related]

  • 37. Beta-catenin antisense treatment decreases beta-catenin expression and tumor growth rate in colon carcinoma xenografts.
    Green DW, Roh H, Pippin JA, Drebin JA.
    J Surg Res; 2001 Nov 29; 101(1):16-20. PubMed ID: 11676549
    [Abstract] [Full Text] [Related]

  • 38. Progesterone crosstalks with insulin-like growth factor signaling in breast cancer cells via induction of insulin receptor substrate-2.
    Cui X, Lazard Z, Zhang P, Hopp TA, Lee AV.
    Oncogene; 2003 Oct 09; 22(44):6937-41. PubMed ID: 14534541
    [Abstract] [Full Text] [Related]

  • 39. Target selectivity of MAPK phosphorothioate antisense ODN on p42/p44, p38 MAPK, and JNK protein expression and its inhibitory effect on VSMC DNA synthesis.
    Huang SL, Ding B, Li J, Yi FX, Liu WL, Yu QS, Guo ZG.
    Zhongguo Yao Li Xue Bao; 1999 Jul 09; 20(7):613-7. PubMed ID: 10678124
    [Abstract] [Full Text] [Related]

  • 40. Rapid induction of IGF-IR signaling in normal and tumor tissue following intravenous injection of IGF-I in mice.
    Lee AV, Taylor ST, Greenall J, Mills JD, Tonge DW, Zhang P, George J, Fiorotto ML, Hadsell DL.
    Horm Metab Res; 2003 Jul 09; 35(11-12):651-5. PubMed ID: 14710342
    [Abstract] [Full Text] [Related]

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