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289 related items for PubMed ID: 15122883

  • 1. Structures of the neuronal and endothelial nitric oxide synthase heme domain with D-nitroarginine-containing dipeptide inhibitors bound.
    Flinspach M, Li H, Jamal J, Yang W, Huang H, Silverman RB, Poulos TL.
    Biochemistry; 2004 May 11; 43(18):5181-7. PubMed ID: 15122883
    [Abstract] [Full Text] [Related]

  • 2. Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
    Flinspach ML, Li H, Jamal J, Yang W, Huang H, Hah JM, Gómez-Vidal JA, Litzinger EA, Silverman RB, Poulos TL.
    Nat Struct Mol Biol; 2004 Jan 11; 11(1):54-9. PubMed ID: 14718923
    [Abstract] [Full Text] [Related]

  • 3. N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase.
    Huang H, Martasek P, Roman LJ, Masters BS, Silverman RB.
    J Med Chem; 1999 Aug 12; 42(16):3147-53. PubMed ID: 10447959
    [Abstract] [Full Text] [Related]

  • 4. Selective inhibition of neuronal nitric oxide synthase by N omega-nitroarginine-and phenylalanine-containing dipeptides and dipeptide esters.
    Silverman RB, Huang H, Marletta MA, Martasek P.
    J Med Chem; 1997 Aug 29; 40(18):2813-7. PubMed ID: 9288162
    [Abstract] [Full Text] [Related]

  • 5. Potent and selective conformationally restricted neuronal nitric oxide synthase inhibitors.
    Gómez-Vidal JA, Martásek P, Roman LJ, Silverman RB.
    J Med Chem; 2004 Jan 29; 47(3):703-10. PubMed ID: 14736250
    [Abstract] [Full Text] [Related]

  • 6. Exploring the binding conformations of bulkier dipeptide amide inhibitors in constitutive nitric oxide synthases.
    Li H, Flinspach ML, Igarashi J, Jamal J, Yang W, Gómez-Vidal JA, Litzinger EA, Huang H, Erdal EP, Silverman RB, Poulos TL.
    Biochemistry; 2005 Nov 22; 44(46):15222-9. PubMed ID: 16285725
    [Abstract] [Full Text] [Related]

  • 7. Aromatic reduced amide bond peptidomimetics as selective inhibitors of neuronal nitric oxide synthase.
    Hah JM, Martásek P, Roman LJ, Silverman RB.
    J Med Chem; 2003 Apr 24; 46(9):1661-9. PubMed ID: 12699384
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and evaluation of dipeptide amides containing N omega-nitroarginine and D-2,4-diaminobutyric acids as inhibitors of neuronal nitric oxide synthase.
    Huang H, Martásek P, Roman LJ, Silverman RB.
    J Enzyme Inhib; 2001 Apr 24; 16(3):233-9. PubMed ID: 11697043
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and evaluation of new sulfur-containing L-arginine-derived inhibitors of nitric oxide synthase.
    Ichimori K, Stuehr DJ, Atkinson RN, King SB.
    J Med Chem; 1999 May 20; 42(10):1842-8. PubMed ID: 10346937
    [Abstract] [Full Text] [Related]

  • 10. Substrate and substrate analog binding to endothelial nitric oxide synthase: electron paramagnetic resonance as an isoform-specific probe of the binding mode of substrate analogs.
    Salerno JC, Martásek P, Williams RF, Masters BS.
    Biochemistry; 1997 Sep 30; 36(39):11821-7. PubMed ID: 9305973
    [Abstract] [Full Text] [Related]

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  • 12. Computer modeling of selective regions in the active site of nitric oxide synthases: implication for the design of isoform-selective inhibitors.
    Ji H, Li H, Flinspach M, Poulos TL, Silverman RB.
    J Med Chem; 2003 Dec 18; 46(26):5700-11. PubMed ID: 14667223
    [Abstract] [Full Text] [Related]

  • 13. N-Phenylamidines as selective inhibitors of human neuronal nitric oxide synthase: structure-activity studies and demonstration of in vivo activity.
    Collins JL, Shearer BG, Oplinger JA, Lee S, Garvey EP, Salter M, Duffy C, Burnette TC, Furfine ES.
    J Med Chem; 1998 Jul 16; 41(15):2858-71. PubMed ID: 9667974
    [Abstract] [Full Text] [Related]

  • 14. Analysis of the kinetics of CO binding to neuronal nitric oxide synthase by flash photolysis: dual effects of substrates, inhibitors, and tetrahydrobiopterin.
    Bengea S, Araki Y, Ito O, Igarashi J, Sagami I, Shimizu T.
    J Inorg Biochem; 2004 Jul 16; 98(7):1210-6. PubMed ID: 15219987
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of vascular nitric oxide after rat chronic brain hypoperfusion: spatial memory and immunocytochemical changes.
    de la Torre JC, Aliev G.
    J Cereb Blood Flow Metab; 2005 Jun 16; 25(6):663-72. PubMed ID: 15703700
    [Abstract] [Full Text] [Related]

  • 16. A tryptophan that modulates tetrahydrobiopterin-dependent electron transfer in nitric oxide synthase regulates enzyme catalysis by additional mechanisms.
    Wang ZQ, Wei CC, Santolini J, Panda K, Wang Q, Stuehr DJ.
    Biochemistry; 2005 Mar 29; 44(12):4676-90. PubMed ID: 15779894
    [Abstract] [Full Text] [Related]

  • 17. The effect of nitric oxide inhibition and temporal expression patterns of the mRNA and protein products of nitric oxide synthase genes during in vitro development of bovine pre-implantation embryos.
    Tesfaye D, Kadanga A, Rings F, Bauch K, Jennen D, Nganvongpanit K, Hölker M, Tholen E, Ponsuksili S, Wimmers K, Montag M, Gilles M, Kirfel G, Herzog V, Schellander K.
    Reprod Domest Anim; 2006 Dec 29; 41(6):501-9. PubMed ID: 17107508
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of nitric oxide synthase isoforms by porphyrins.
    Wolff DJ, Naddelman RA, Lubeskie A, Saks DA.
    Arch Biochem Biophys; 1996 Sep 01; 333(1):27-34. PubMed ID: 8806750
    [Abstract] [Full Text] [Related]

  • 19. Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoakyl]aminopentyl)-N'-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase.
    Hah JM, Roman LJ, Martásek P, Silverman RB.
    J Med Chem; 2001 Aug 02; 44(16):2667-70. PubMed ID: 11472219
    [Abstract] [Full Text] [Related]

  • 20. Structural basis for isoform-selective inhibition in nitric oxide synthase.
    Poulos TL, Li H.
    Acc Chem Res; 2013 Feb 19; 46(2):390-8. PubMed ID: 23030042
    [Abstract] [Full Text] [Related]

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