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83 related items for PubMed ID: 15131241

  • 1. Differential involvement of multidrug resistance-associated protein 1 and P-glycoprotein in tissue distribution and excretion of grepafloxacin in mice.
    Sasabe H, Kato Y, Suzuki T, Itose M, Miyamoto G, Sugiyama Y.
    J Pharmacol Exp Ther; 2004 Aug; 310(2):648-55. PubMed ID: 15131241
    [Abstract] [Full Text] [Related]

  • 2. Altered expression of hepatic cytochromes P-450 in mice deficient in one or more mdr1 genes.
    Schuetz EG, Umbenhauer DR, Yasuda K, Brimer C, Nguyen L, Relling MV, Schuetz JD, Schinkel AH.
    Mol Pharmacol; 2000 Jan; 57(1):188-97. PubMed ID: 10617694
    [Abstract] [Full Text] [Related]

  • 3. Pharmacokinetics and pharmacodynamics of alfentanil in P-glycoprotein-competent and P-glycoprotein-deficient mice: P-glycoprotein efflux alters alfentanil brain disposition and antinociception.
    Kalvass JC, Olson ER, Pollack GM.
    Drug Metab Dispos; 2007 Mar; 35(3):455-9. PubMed ID: 17178769
    [Abstract] [Full Text] [Related]

  • 4. Blonanserin, a novel atypical antipsychotic agent not actively transported as substrate by P-glycoprotein.
    Inoue T, Osada K, Tagawa M, Ogawa Y, Haga T, Sogame Y, Hashizume T, Watanabe T, Taguchi A, Katsumata T, Yabuki M, Yamaguchi N.
    Prog Neuropsychopharmacol Biol Psychiatry; 2012 Oct 01; 39(1):156-62. PubMed ID: 22691713
    [Abstract] [Full Text] [Related]

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  • 6. Mechanism for the tissue distribution of grepafloxacin, a fluoroquinolone antibiotic, in rats.
    Suzuki T, Kato Y, Sasabe H, Itose M, Miyamoto G, Sugiyama Y.
    Drug Metab Dispos; 2002 Dec 01; 30(12):1393-9. PubMed ID: 12433809
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  • 8. Effect of P-glycoprotein on the pharmacokinetics and tissue distribution of enaminone anticonvulsants: analysis by population and physiological approaches.
    Cox DS, Scott KR, Gao H, Eddington ND.
    J Pharmacol Exp Ther; 2002 Sep 01; 302(3):1096-104. PubMed ID: 12183668
    [Abstract] [Full Text] [Related]

  • 9. Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats.
    Sasabe H, Tsuji A, Sugiyama Y.
    J Pharmacol Exp Ther; 1998 Mar 01; 284(3):1033-9. PubMed ID: 9495864
    [Abstract] [Full Text] [Related]

  • 10. Distribution of STI-571 to the brain is limited by P-glycoprotein-mediated efflux.
    Dai H, Marbach P, Lemaire M, Hayes M, Elmquist WF.
    J Pharmacol Exp Ther; 2003 Mar 01; 304(3):1085-92. PubMed ID: 12604685
    [Abstract] [Full Text] [Related]

  • 11. Multidrug resistance protein 2 is an important determinant of paclitaxel pharmacokinetics.
    Lagas JS, Vlaming ML, van Tellingen O, Wagenaar E, Jansen RS, Rosing H, Beijnen JH, Schinkel AH.
    Clin Cancer Res; 2006 Oct 15; 12(20 Pt 1):6125-32. PubMed ID: 17062689
    [Abstract] [Full Text] [Related]

  • 12. Altered disposition and antinociception of [D-penicillamine(2,5)] enkephalin in mdr1a-gene-deficient mice.
    Chen C, Pollack GM.
    J Pharmacol Exp Ther; 1998 Nov 15; 287(2):545-52. PubMed ID: 9808679
    [Abstract] [Full Text] [Related]

  • 13. Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein.
    van Asperen J, van Tellingen O, Tijssen F, Schinkel AH, Beijnen JH.
    Br J Cancer; 1999 Jan 15; 79(1):108-13. PubMed ID: 10408701
    [Abstract] [Full Text] [Related]

  • 14. P-glycoprotein (Abcb1) is involved in absorptive drug transport in skin.
    Ito K, Nguyen HT, Kato Y, Wakayama T, Kubo Y, Iseki S, Tsuji A.
    J Control Release; 2008 Nov 12; 131(3):198-204. PubMed ID: 18725258
    [Abstract] [Full Text] [Related]

  • 15. Limited distribution of new quinolone antibacterial agents into brain caused by multiple efflux transporters at the blood-brain barrier.
    Tamai I, Yamashita J, Kido Y, Ohnari A, Sai Y, Shima Y, Naruhashi K, Koizumi S, Tsuji A.
    J Pharmacol Exp Ther; 2000 Oct 12; 295(1):146-52. PubMed ID: 10991972
    [Abstract] [Full Text] [Related]

  • 16. Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.
    Schinkel AH, Wagenaar E, van Deemter L, Mol CA, Borst P.
    J Clin Invest; 1995 Oct 12; 96(4):1698-705. PubMed ID: 7560060
    [Abstract] [Full Text] [Related]

  • 17. The pharmacological phenotype of combined multidrug-resistance mdr1a/1b- and mrp1-deficient mice.
    Johnson DR, Finch RA, Lin ZP, Zeiss CJ, Sartorelli AC.
    Cancer Res; 2001 Feb 15; 61(4):1469-76. PubMed ID: 11245453
    [Abstract] [Full Text] [Related]

  • 18. Transbilayer movement of NBD-labeled phospholipids in red blood cell membranes: outward-directed transport by the multidrug resistance protein 1 (MRP1).
    Dekkers DW, Comfurius P, Schroit AJ, Bevers EM, Zwaal RF.
    Biochemistry; 1998 Oct 20; 37(42):14833-7. PubMed ID: 9778357
    [Abstract] [Full Text] [Related]

  • 19. The impact of pharmacologic and genetic knockout of P-glycoprotein on nelfinavir levels in the brain and other tissues in mice.
    Salama NN, Kelly EJ, Bui T, Ho RJ.
    J Pharm Sci; 2005 Jun 20; 94(6):1216-25. PubMed ID: 15858856
    [Abstract] [Full Text] [Related]

  • 20. Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis.
    Kubota H, Ishihara H, Langmann T, Schmitz G, Stieger B, Wieser HG, Yonekawa Y, Frei K.
    Epilepsy Res; 2006 Mar 20; 68(3):213-28. PubMed ID: 16361082
    [Abstract] [Full Text] [Related]

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