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323 related items for PubMed ID: 15134431

  • 1. No need to be HAMLET or BAMLET to interact with histones: binding of monomeric alpha-lactalbumin to histones and basic poly-amino acids.
    Permyakov SE, Pershikova IV, Khokhlova TI, Uversky VN, Permyakov EA.
    Biochemistry; 2004 May 18; 43(19):5575-82. PubMed ID: 15134431
    [Abstract] [Full Text] [Related]

  • 2. Who is Mr. HAMLET? Interaction of human alpha-lactalbumin with monomeric oleic acid.
    Knyazeva EL, Grishchenko VM, Fadeev RS, Akatov VS, Permyakov SE, Permyakov EA.
    Biochemistry; 2008 Dec 09; 47(49):13127-37. PubMed ID: 19006329
    [Abstract] [Full Text] [Related]

  • 3. Stability of HAMLET--a kinetically trapped alpha-lactalbumin oleic acid complex.
    Fast J, Mossberg AK, Svanborg C, Linse S.
    Protein Sci; 2005 Feb 09; 14(2):329-40. PubMed ID: 15659367
    [Abstract] [Full Text] [Related]

  • 4. Conversion of human alpha-lactalbumin to an apo-like state in the complexes with basic poly-amino acids: toward understanding of the molecular mechanism of antitumor action of HAMLET.
    Permyakov SE, Pershikova IV, Zhadan AP, Goers J, Bakunts AG, Uversky VN, Berliner LJ, Permyakov EA.
    J Proteome Res; 2005 Feb 09; 4(2):564-9. PubMed ID: 15822935
    [Abstract] [Full Text] [Related]

  • 5. Alpha-lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells).
    Svensson M, Fast J, Mossberg AK, Düringer C, Gustafsson L, Hallgren O, Brooks CL, Berliner L, Linse S, Svanborg C.
    Protein Sci; 2003 Dec 09; 12(12):2794-804. PubMed ID: 14627739
    [Abstract] [Full Text] [Related]

  • 6. How to improve nature: study of the electrostatic properties of the surface of alpha-lactalbumin.
    Permyakov SE, Makhatadze GI, Owenius R, Uversky VN, Brooks CL, Permyakov EA, Berliner LJ.
    Protein Eng Des Sel; 2005 Sep 09; 18(9):425-33. PubMed ID: 16093284
    [Abstract] [Full Text] [Related]

  • 7. Molten globule of bovine alpha-lactalbumin at neutral pH induced by heat, trifluoroethanol, and oleic acid: a comparative analysis by circular dichroism spectroscopy and limited proteolysis.
    Polverino de Laureto P, Frare E, Gottardo R, Fontana A.
    Proteins; 2002 Nov 15; 49(3):385-97. PubMed ID: 12360528
    [Abstract] [Full Text] [Related]

  • 8. Electrostatic interactions play an essential role in the binding of oleic acid with α-lactalbumin in the HAMLET-like complex: a study using charge-specific chemical modifications.
    Xie Y, Min S, Harte NP, Kirk H, O'Brien JE, Voorheis HP, Svanborg C, Hun Mok K.
    Proteins; 2013 Jan 15; 81(1):1-17. PubMed ID: 22777854
    [Abstract] [Full Text] [Related]

  • 9. Cytotoxic aggregates of alpha-lactalbumin induced by unsaturated fatty acid induce apoptosis in tumor cells.
    Zhang M, Yang F, Yang F, Chen J, Zheng CY, Liang Y.
    Chem Biol Interact; 2009 Jul 15; 180(2):131-42. PubMed ID: 19497410
    [Abstract] [Full Text] [Related]

  • 10. A novel method for preparation of HAMLET-like protein complexes.
    Permyakov SE, Knyazeva EL, Leonteva MV, Fadeev RS, Chekanov AV, Zhadan AP, Håkansson AP, Akatov VS, Permyakov EA.
    Biochimie; 2011 Sep 15; 93(9):1495-501. PubMed ID: 21596091
    [Abstract] [Full Text] [Related]

  • 11. Structure and function of human α-lactalbumin made lethal to tumor cells (HAMLET)-type complexes.
    Mossberg AK, Hun Mok K, Morozova-Roche LA, Svanborg C.
    FEBS J; 2010 Nov 15; 277(22):4614-25. PubMed ID: 20977665
    [Abstract] [Full Text] [Related]

  • 12. α-Lactalbumin forms with oleic acid a high molecular weight complex displaying cytotoxic activity.
    Spolaore B, Pinato O, Canton M, Zambonin M, Polverino de Laureto P, Fontana A.
    Biochemistry; 2010 Oct 05; 49(39):8658-67. PubMed ID: 20804154
    [Abstract] [Full Text] [Related]

  • 13. Zinc binding in bovine alpha-lactalbumin: sequence homology may not be a predictor of subtle functional features.
    Permyakov SE, Veprintsev DB, Brooks CL, Permyakov EA, Berliner LJ.
    Proteins; 2000 Jul 01; 40(1):106-11. PubMed ID: 10813835
    [Abstract] [Full Text] [Related]

  • 14. Structure and stability analysis of cytotoxic complex of camel α-lactalbumin and unsaturated fatty acids produced at high temperature.
    Atri MS, Saboury AA, Moosavi-Movahedi AA, Goliaei B, Sefidbakht Y, Alijanvand HH, Sharifzadeh A, Niasari-Naslaji A.
    J Biomol Struct Dyn; 2011 Jun 01; 28(6):919-28. PubMed ID: 21469752
    [Abstract] [Full Text] [Related]

  • 15. alpha-Lactalbumin, engineered to be nonnative and inactive, kills tumor cells when in complex with oleic acid: a new biological function resulting from partial unfolding.
    Pettersson-Kastberg J, Mossberg AK, Trulsson M, Yong YJ, Min S, Lim Y, O'Brien JE, Svanborg C, Mok KH.
    J Mol Biol; 2009 Dec 18; 394(5):994-1010. PubMed ID: 19766653
    [Abstract] [Full Text] [Related]

  • 16. Histone deacetylase inhibitors promote the tumoricidal effect of HAMLET.
    Brest P, Gustafsson M, Mossberg AK, Gustafsson L, Duringer C, Hamiche A, Svanborg C.
    Cancer Res; 2007 Dec 01; 67(23):11327-34. PubMed ID: 18056459
    [Abstract] [Full Text] [Related]

  • 17. The effect of proteolysis on the induction of cell death by monomeric alpha-lactalbumin.
    Brück WM, Gibson GR, Brück TB.
    Biochimie; 2014 Feb 01; 97():138-43. PubMed ID: 24139905
    [Abstract] [Full Text] [Related]

  • 18. alpha-Lactalbumin species variation, HAMLET formation, and tumor cell death.
    Pettersson J, Mossberg AK, Svanborg C.
    Biochem Biophys Res Commun; 2006 Jun 23; 345(1):260-70. PubMed ID: 16678133
    [Abstract] [Full Text] [Related]

  • 19. Compact oleic acid in HAMLET.
    Fast J, Mossberg AK, Nilsson H, Svanborg C, Akke M, Linse S.
    FEBS Lett; 2005 Nov 07; 579(27):6095-100. PubMed ID: 16229842
    [Abstract] [Full Text] [Related]

  • 20. Heat-treatment method for producing fatty acid-bound alpha-lactalbumin that induces tumor cell death.
    Kamijima T, Ohmura A, Sato T, Akimoto K, Itabashi M, Mizuguchi M, Kamiya M, Kikukawa T, Aizawa T, Takahashi M, Kawano K, Demura M.
    Biochem Biophys Res Commun; 2008 Nov 07; 376(1):211-4. PubMed ID: 18774773
    [Abstract] [Full Text] [Related]

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