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372 related items for PubMed ID: 15134437

  • 1. Differential effects of substrate on type I and type II PKA holoenzyme dissociation.
    Vigil D, Blumenthal DK, Brown S, Taylor SS, Trewhella J.
    Biochemistry; 2004 May 18; 43(19):5629-36. PubMed ID: 15134437
    [Abstract] [Full Text] [Related]

  • 2. Probing cAMP-dependent protein kinase holoenzyme complexes I alpha and II beta by FT-IR and chemical protein footprinting.
    Yu S, Mei FC, Lee JC, Cheng X.
    Biochemistry; 2004 Feb 24; 43(7):1908-20. PubMed ID: 14967031
    [Abstract] [Full Text] [Related]

  • 3. Conformational differences among solution structures of the type Ialpha, IIalpha and IIbeta protein kinase A regulatory subunit homodimers: role of the linker regions.
    Vigil D, Blumenthal DK, Heller WT, Brown S, Canaves JM, Taylor SS, Trewhella J.
    J Mol Biol; 2004 Apr 09; 337(5):1183-94. PubMed ID: 15046986
    [Abstract] [Full Text] [Related]

  • 4. Mapping intersubunit interactions of the regulatory subunit (RIalpha) in the type I holoenzyme of protein kinase A by amide hydrogen/deuterium exchange mass spectrometry (DXMS).
    Hamuro Y, Anand GS, Kim JS, Juliano C, Stranz DD, Taylor SS, Woods VL.
    J Mol Biol; 2004 Jul 23; 340(5):1185-96. PubMed ID: 15236976
    [Abstract] [Full Text] [Related]

  • 5. Cyclic-AMP and pseudosubstrate effects on type-I A-kinase regulatory and catalytic subunit binding kinetics.
    Anand G, Taylor SS, Johnson DA.
    Biochemistry; 2007 Aug 14; 46(32):9283-91. PubMed ID: 17658893
    [Abstract] [Full Text] [Related]

  • 6. Mechanism of activation of cAMP-dependent protein kinase: in Mucor rouxii the apparent specific activity of the cAMP-activated holoenzyme is different than that of its free catalytic subunit.
    Zaremberg V, Donella-Deana A, Moreno S.
    Arch Biochem Biophys; 2000 Sep 01; 381(1):74-82. PubMed ID: 11019822
    [Abstract] [Full Text] [Related]

  • 7. Solution scattering reveals large differences in the global structures of type II protein kinase A isoforms.
    Vigil D, Blumenthal DK, Taylor SS, Trewhella J.
    J Mol Biol; 2006 Mar 31; 357(3):880-9. PubMed ID: 16460759
    [Abstract] [Full Text] [Related]

  • 8. Novel, isotype-specific sensors for protein kinase A subunit interaction based on bioluminescence resonance energy transfer (BRET).
    Prinz A, Diskar M, Erlbruch A, Herberg FW.
    Cell Signal; 2006 Oct 31; 18(10):1616-25. PubMed ID: 16524697
    [Abstract] [Full Text] [Related]

  • 9. The roles of the RIIβ linker and N-terminal cyclic nucleotide-binding domain in determining the unique structures of the type IIβ protein kinase A: a small angle x-ray and neutron scattering study.
    Blumenthal DK, Copps J, Smith-Nguyen EV, Zhang P, Heller WT, Taylor SS.
    J Biol Chem; 2014 Oct 10; 289(41):28505-12. PubMed ID: 25112875
    [Abstract] [Full Text] [Related]

  • 10. Molecular basis for isoform-specific autoregulation of protein kinase A.
    Diskar M, Zenn HM, Kaupisch A, Prinz A, Herberg FW.
    Cell Signal; 2007 Oct 10; 19(10):2024-34. PubMed ID: 17614255
    [Abstract] [Full Text] [Related]

  • 11. Compensatory stabilization of RIIbeta protein, cell cycle deregulation, and growth arrest in colon and prostate carcinoma cells by antisense-directed down-regulation of protein kinase A RIalpha protein.
    Nesterova M, Noguchi K, Park YG, Lee YN, Cho-Chung YS.
    Clin Cancer Res; 2000 Sep 10; 6(9):3434-41. PubMed ID: 10999726
    [Abstract] [Full Text] [Related]

  • 12. PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation.
    Kim C, Cheng CY, Saldanha SA, Taylor SS.
    Cell; 2007 Sep 21; 130(6):1032-43. PubMed ID: 17889648
    [Abstract] [Full Text] [Related]

  • 13. Active site mutations define the pathway for the cooperative activation of cAMP-dependent protein kinase.
    Herberg FW, Taylor SS, Dostmann WR.
    Biochemistry; 1996 Mar 05; 35(9):2934-42. PubMed ID: 8608131
    [Abstract] [Full Text] [Related]

  • 14. Crystal structures of RIalpha subunit of cyclic adenosine 5'-monophosphate (cAMP)-dependent protein kinase complexed with (Rp)-adenosine 3',5'-cyclic monophosphothioate and (Sp)-adenosine 3',5'-cyclic monophosphothioate, the phosphothioate analogues of cAMP.
    Wu J, Jones JM, Nguyen-Huu X, Ten Eyck LF, Taylor SS.
    Biochemistry; 2004 Jun 01; 43(21):6620-9. PubMed ID: 15157095
    [Abstract] [Full Text] [Related]

  • 15. Isoform specific differences in binding of a dual-specificity A-kinase anchoring protein to type I and type II regulatory subunits of PKA.
    Burns LL, Canaves JM, Pennypacker JK, Blumenthal DK, Taylor SS.
    Biochemistry; 2003 May 20; 42(19):5754-63. PubMed ID: 12741833
    [Abstract] [Full Text] [Related]

  • 16. Dynamic binding of PKA regulatory subunit RI alpha.
    Gullingsrud J, Kim C, Taylor SS, McCammon JA.
    Structure; 2006 Jan 20; 14(1):141-9. PubMed ID: 16407073
    [Abstract] [Full Text] [Related]

  • 17. Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP.
    Lu TW, Wu J, Aoto PC, Weng JH, Ahuja LG, Sun N, Cheng CY, Zhang P, Taylor SS.
    Proc Natl Acad Sci U S A; 2019 Aug 13; 116(33):16347-16356. PubMed ID: 31363049
    [Abstract] [Full Text] [Related]

  • 18. Identification and characterization of novel PKA holoenzymes in human T lymphocytes.
    Orstavik S, Funderud A, Hafte TT, Eikvar S, Jahnsen T, Skålhegg BS.
    FEBS J; 2005 Apr 13; 272(7):1559-67. PubMed ID: 15794744
    [Abstract] [Full Text] [Related]

  • 19. Antisense protein kinase A RIalpha inhibits 7,12-dimethylbenz(a)anthracene-induction of mammary cancer: blockade at the initial phase of carcinogenesis.
    Nesterova MV, Cho-Chung YS.
    Clin Cancer Res; 2004 Jul 01; 10(13):4568-77. PubMed ID: 15240549
    [Abstract] [Full Text] [Related]

  • 20. Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA.
    Kim C, Xuong NH, Taylor SS.
    Science; 2005 Feb 04; 307(5710):690-6. PubMed ID: 15692043
    [Abstract] [Full Text] [Related]

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