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300 related items for PubMed ID: 15141020

  • 1. Topoisomerase poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated-dependent and -independent mechanisms.
    Siu WY, Lau A, Arooz T, Chow JP, Ho HT, Poon RY.
    Mol Cancer Ther; 2004 May; 3(5):621-32. PubMed ID: 15141020
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  • 2. Transcription-dependent activation of ataxia telangiectasia mutated prevents DNA-dependent protein kinase-mediated cell death in response to topoisomerase I poison.
    Sakasai R, Teraoka H, Takagi M, Tibbetts RS.
    J Biol Chem; 2010 May 14; 285(20):15201-15208. PubMed ID: 20304914
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  • 3. Phosphorylation of p53 on Ser15 during cell cycle caused by Topo I and Topo II inhibitors in relation to ATM and Chk2 activation.
    Zhao H, Traganos F, Darzynkiewicz Z.
    Cell Cycle; 2008 Oct 14; 7(19):3048-55. PubMed ID: 18802408
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  • 8. ERK1/2 signaling plays an important role in topoisomerase II poison-induced G2/M checkpoint activation.
    Kolb RH, Greer PM, Cao PT, Cowan KH, Yan Y.
    PLoS One; 2012 Oct 14; 7(11):e50281. PubMed ID: 23166842
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  • 9. Caffeine inhibits checkpoint responses without inhibiting the ataxia-telangiectasia-mutated (ATM) and ATM- and Rad3-related (ATR) protein kinases.
    Cortez D.
    J Biol Chem; 2003 Sep 26; 278(39):37139-45. PubMed ID: 12847089
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  • 12. Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive.
    Guo N, Faller DV, Vaziri C.
    Cell Growth Differ; 2002 Feb 26; 13(2):77-86. PubMed ID: 11864911
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  • 14. Etoposide and adriamycin but not genistein can activate the checkpoint kinase Chk2 independently of ATM/ATR.
    Théard D, Coisy M, Ducommun B, Concannon P, Darbon JM.
    Biochem Biophys Res Commun; 2001 Dec 21; 289(5):1199-204. PubMed ID: 11741320
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  • 15. S phase entry causes homocysteine-induced death while ataxia telangiectasia and Rad3 related protein functions anti-apoptotically to protect neurons.
    Ye W, Blain SW.
    Brain; 2010 Aug 21; 133(Pt 8):2295-312. PubMed ID: 20639548
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  • 17. Activation of the S phase DNA damage checkpoint by mitomycin C.
    Mladenov E, Tsaneva I, Anachkova B.
    J Cell Physiol; 2007 May 21; 211(2):468-76. PubMed ID: 17167777
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  • 18. Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity.
    Zhou BB, Chaturvedi P, Spring K, Scott SP, Johanson RA, Mishra R, Mattern MR, Winkler JD, Khanna KK.
    J Biol Chem; 2000 Apr 07; 275(14):10342-8. PubMed ID: 10744722
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  • 20. Stalled replication induces p53 accumulation through distinct mechanisms from DNA damage checkpoint pathways.
    Ho CC, Siu WY, Lau A, Chan WM, Arooz T, Poon RY.
    Cancer Res; 2006 Feb 15; 66(4):2233-41. PubMed ID: 16489026
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