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Journal Abstract Search

208 related items for PubMed ID: 15146479

  • 1.
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  • 2. Structure of human aldose reductase holoenzyme in complex with statil: an approach to structure-based inhibitor design of the enzyme.
    El-Kabbani O, Ramsland P, Darmanin C, Chung RP, Podjarny A.
    Proteins; 2003 Feb 01; 50(2):230-8. PubMed ID: 12486717
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  • 3. High-resolution structures of human aldose reductase holoenzyme in complex with stereoisomers of the potent inhibitor Fidarestat: stereospecific interaction between the enzyme and a cyclic imide type inhibitor.
    El-Kabbani O, Darmanin C, Oka M, Schulze-Briese C, Tomizaki T, Hazemann I, Mitschler A, Podjarny A.
    J Med Chem; 2004 Aug 26; 47(18):4530-7. PubMed ID: 15317464
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  • 4. Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity.
    El-Kabbani O, Carbone V, Darmanin C, Oka M, Mitschler A, Podjarny A, Schulze-Briese C, Chung RP.
    J Med Chem; 2005 Aug 25; 48(17):5536-42. PubMed ID: 16107153
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  • 6. The crystallographic structure of the aldose reductase-IDD552 complex shows direct proton donation from tyrosine 48.
    Ruiz F, Hazemann I, Mitschler A, Joachimiak A, Schneider T, Karplus M, Podjarny A.
    Acta Crystallogr D Biol Crystallogr; 2004 Aug 25; 60(Pt 8):1347-54. PubMed ID: 15272156
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  • 8. Ultrahigh resolution drug design I: details of interactions in human aldose reductase-inhibitor complex at 0.66 A.
    Howard EI, Sanishvili R, Cachau RE, Mitschler A, Chevrier B, Barth P, Lamour V, Van Zandt M, Sibley E, Bon C, Moras D, Schneider TR, Joachimiak A, Podjarny A.
    Proteins; 2004 Jun 01; 55(4):792-804. PubMed ID: 15146478
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  • 11. X-ray structure of the V301L aldo-keto reductase 1B10 complexed with NADP(+) and the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity.
    Ruiz FX, Cousido-Siah A, Mitschler A, Farrés J, Parés X, Podjarny A.
    Chem Biol Interact; 2013 Feb 25; 202(1-3):178-85. PubMed ID: 23295227
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  • 14. Molecular modeling studies of the binding modes of aldose reductase inhibitors at the active site of human aldose reductase.
    Lee YS, Chen Z, Kador PF.
    Bioorg Med Chem; 1998 Oct 25; 6(10):1811-9. PubMed ID: 9839011
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  • 15. Aldose and aldehyde reductases: structure-function studies on the coenzyme and inhibitor-binding sites.
    El-Kabbani O, Old SE, Ginell SL, Carper DA.
    Mol Vis; 1999 Sep 03; 5():20. PubMed ID: 10493777
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  • 16. Structure of aldehyde reductase in ternary complex with a 5-arylidene-2,4-thiazolidinedione aldose reductase inhibitor.
    Carbone V, Giglio M, Chung R, Huyton T, Adams J, Maccari R, Ottana R, Hara A, El-Kabbani O.
    Eur J Med Chem; 2010 Mar 03; 45(3):1140-5. PubMed ID: 20036445
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  • 17. Subatomic and atomic crystallographic studies of aldose reductase: implications for inhibitor binding.
    Podjarny A, Cachau RE, Schneider T, Van Zandt M, Joachimiak A.
    Cell Mol Life Sci; 2004 Apr 03; 61(7-8):763-73. PubMed ID: 15095001
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  • 19. Correlation of binding constants and molecular modelling of inhibitors in the active sites of aldose reductase and aldehyde reductase.
    Carbone V, Zhao HT, Chung R, Endo S, Hara A, El-Kabbani O.
    Bioorg Med Chem; 2009 Feb 01; 17(3):1244-50. PubMed ID: 19121944
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