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197 related items for PubMed ID: 15155760

  • 1. Trypanosoma brucei and Trypanosoma cruzi tryparedoxin peroxidases catalytically detoxify peroxynitrite via oxidation of fast reacting thiols.
    Trujillo M, Budde H, Piñeyro MD, Stehr M, Robello C, Flohé L, Radi R.
    J Biol Chem; 2004 Aug 13; 279(33):34175-82. PubMed ID: 15155760
    [Abstract] [Full Text] [Related]

  • 2. Tryparedoxin peroxidases from Trypanosoma cruzi: high efficiency in the catalytic elimination of hydrogen peroxide and peroxynitrite.
    Piñeyro MD, Arcari T, Robello C, Radi R, Trujillo M.
    Arch Biochem Biophys; 2011 Mar 15; 507(2):287-95. PubMed ID: 21167808
    [Abstract] [Full Text] [Related]

  • 3. The trypanothione-thiol system in Trypanosoma cruzi as a key antioxidant mechanism against peroxynitrite-mediated cytotoxicity.
    Thomson L, Denicola A, Radi R.
    Arch Biochem Biophys; 2003 Apr 01; 412(1):55-64. PubMed ID: 12646268
    [Abstract] [Full Text] [Related]

  • 4. A second class of peroxidases linked to the trypanothione metabolism.
    Hillebrand H, Schmidt A, Krauth-Siegel RL.
    J Biol Chem; 2003 Feb 28; 278(9):6809-15. PubMed ID: 12466271
    [Abstract] [Full Text] [Related]

  • 5. A tryparedoxin-coupled biosensor reveals a mitochondrial trypanothione metabolism in trypanosomes.
    Ebersoll S, Bogacz M, Günter LM, Dick TP, Krauth-Siegel RL.
    Elife; 2020 Jan 31; 9():. PubMed ID: 32003744
    [Abstract] [Full Text] [Related]

  • 6. Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite.
    Piacenza L, Peluffo G, Alvarez MN, Kelly JM, Wilkinson SR, Radi R.
    Biochem J; 2008 Mar 01; 410(2):359-68. PubMed ID: 17973627
    [Abstract] [Full Text] [Related]

  • 7. Substrate specificity, localization, and essential role of the glutathione peroxidase-type tryparedoxin peroxidases in Trypanosoma brucei.
    Schlecker T, Schmidt A, Dirdjaja N, Voncken F, Clayton C, Krauth-Siegel RL.
    J Biol Chem; 2005 Apr 15; 280(15):14385-94. PubMed ID: 15664987
    [Abstract] [Full Text] [Related]

  • 8. Kinetics of peroxiredoxins and their role in the decomposition of peroxynitrite.
    Trujillo M, Ferrer-Sueta G, Thomson L, Flohé L, Radi R.
    Subcell Biochem; 2007 Apr 15; 44():83-113. PubMed ID: 18084891
    [Abstract] [Full Text] [Related]

  • 9. The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin.
    Wilkinson SR, Meyer DJ, Taylor MC, Bromley EV, Miles MA, Kelly JM.
    J Biol Chem; 2002 May 10; 277(19):17062-71. PubMed ID: 11842085
    [Abstract] [Full Text] [Related]

  • 10. Structural and molecular basis of the peroxynitrite-mediated nitration and inactivation of Trypanosoma cruzi iron-superoxide dismutases (Fe-SODs) A and B: disparate susceptibilities due to the repair of Tyr35 radical by Cys83 in Fe-SODB through intramolecular electron transfer.
    Martinez A, Peluffo G, Petruk AA, Hugo M, Piñeyro D, Demicheli V, Moreno DM, Lima A, Batthyány C, Durán R, Robello C, Martí MA, Larrieux N, Buschiazzo A, Trujillo M, Radi R, Piacenza L.
    J Biol Chem; 2014 May 02; 289(18):12760-78. PubMed ID: 24616096
    [Abstract] [Full Text] [Related]

  • 11. Kinetics and redox-sensitive oligomerisation reveal negative subunit cooperativity in tryparedoxin peroxidase of Trypanosoma brucei brucei.
    Budde H, Flohé L, Hecht HJ, Hofmann B, Stehr M, Wissing J, Lünsdorf H.
    Biol Chem; 2003 Apr 02; 384(4):619-33. PubMed ID: 12751791
    [Abstract] [Full Text] [Related]

  • 12. Glutathionylation of trypanosomal thiol redox proteins.
    Melchers J, Dirdjaja N, Ruppert T, Krauth-Siegel RL.
    J Biol Chem; 2007 Mar 23; 282(12):8678-94. PubMed ID: 17242409
    [Abstract] [Full Text] [Related]

  • 13. The trypanothione system.
    Krauth-Siegel LR, Comini MA, Schlecker T.
    Subcell Biochem; 2007 Mar 23; 44():231-51. PubMed ID: 18084897
    [Abstract] [Full Text] [Related]

  • 14. Tryparedoxins from Crithidia fasciculata and Trypanosoma brucei: photoreduction of the redox disulfide using synchrotron radiation and evidence for a conformational switch implicated in function.
    Alphey MS, Gabrielsen M, Micossi E, Leonard GA, McSweeney SM, Ravelli RB, Tetaud E, Fairlamb AH, Bond CS, Hunter WN.
    J Biol Chem; 2003 Jul 11; 278(28):25919-25. PubMed ID: 12707277
    [Abstract] [Full Text] [Related]

  • 15. Redox metabolism in Trypanosoma cruzi: functional characterization of tryparedoxins revisited.
    Arias DG, Marquez VE, Chiribao ML, Gadelha FR, Robello C, Iglesias AA, Guerrero SA.
    Free Radic Biol Med; 2013 Oct 11; 63():65-77. PubMed ID: 23665397
    [Abstract] [Full Text] [Related]

  • 16. Trypanothione-dependent synthesis of deoxyribonucleotides by Trypanosoma brucei ribonucleotide reductase.
    Dormeyer M, Reckenfelderbäumer N, Ludemann H, Krauth-Siegel RL.
    J Biol Chem; 2001 Apr 06; 276(14):10602-6. PubMed ID: 11150302
    [Abstract] [Full Text] [Related]

  • 17. A single enzyme catalyses formation of Trypanothione from glutathione and spermidine in Trypanosoma cruzi.
    Oza SL, Tetaud E, Ariyanayagam MR, Warnon SS, Fairlamb AH.
    J Biol Chem; 2002 Sep 27; 277(39):35853-61. PubMed ID: 12121990
    [Abstract] [Full Text] [Related]

  • 18. Gamma-glutamylcysteine synthetase and tryparedoxin 1 exert high control on the antioxidant system in Trypanosoma cruzi contributing to drug resistance and infectivity.
    González-Chávez Z, Vázquez C, Mejia-Tlachi M, Márquez-Dueñas C, Manning-Cela R, Encalada R, Rodríguez-Enríquez S, Michels PAM, Moreno-Sánchez R, Saavedra E.
    Redox Biol; 2019 Sep 27; 26():101231. PubMed ID: 31203195
    [Abstract] [Full Text] [Related]

  • 19. Crystal structure of the tryparedoxin peroxidase from the human parasite Trypanosoma cruzi.
    Piñeyro MD, Pizarro JC, Lema F, Pritsch O, Cayota A, Bentley GA, Robello C.
    J Struct Biol; 2005 Apr 27; 150(1):11-22. PubMed ID: 15797726
    [Abstract] [Full Text] [Related]

  • 20. Catalytic characteristics of tryparedoxin.
    Gommel DU, Nogoceke E, Morr M, Kiess M, Kalisz HM, Flohé L.
    Eur J Biochem; 1997 Sep 15; 248(3):913-8. PubMed ID: 9342246
    [Abstract] [Full Text] [Related]

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