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Journal Abstract Search

704 related items for PubMed ID: 15156201

  • 1. mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.
    Majumder PK, Febbo PG, Bikoff R, Berger R, Xue Q, McMahon LM, Manola J, Brugarolas J, McDonnell TJ, Golub TR, Loda M, Lane HA, Sellers WR.
    Nat Med; 2004 Jun; 10(6):594-601. PubMed ID: 15156201
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity.
    deGraffenried LA, Friedrichs WE, Russell DH, Donzis EJ, Middleton AK, Silva JM, Roth RA, Hidalgo M.
    Clin Cancer Res; 2004 Dec 01; 10(23):8059-67. PubMed ID: 15585641
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras.
    Wislez M, Spencer ML, Izzo JG, Juroske DM, Balhara K, Cody DD, Price RE, Hittelman WN, Wistuba II, Kurie JM.
    Cancer Res; 2005 Apr 15; 65(8):3226-35. PubMed ID: 15833854
    [Abstract] [Full Text] [Related]

  • 4. AMP-activated protein kinase activity is required for vanadate-induced hypoxia-inducible factor 1alpha expression in DU145 cells.
    Hwang JT, Lee M, Jung SN, Lee HJ, Kang I, Kim SS, Ha J.
    Carcinogenesis; 2004 Dec 15; 25(12):2497-507. PubMed ID: 15297373
    [Abstract] [Full Text] [Related]

  • 5. Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum.
    Wlodarski P, Kasprzycka M, Liu X, Marzec M, Robertson ES, Slupianek A, Wasik MA.
    Cancer Res; 2005 Sep 01; 65(17):7800-8. PubMed ID: 16140948
    [Abstract] [Full Text] [Related]

  • 6. Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt.
    Asnaghi L, Calastretti A, Bevilacqua A, D'Agnano I, Gatti G, Canti G, Delia D, Capaccioli S, Nicolin A.
    Oncogene; 2004 Jul 29; 23(34):5781-91. PubMed ID: 15208671
    [Abstract] [Full Text] [Related]

  • 7. A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.
    Sekulić A, Hudson CC, Homme JL, Yin P, Otterness DM, Karnitz LM, Abraham RT.
    Cancer Res; 2000 Jul 01; 60(13):3504-13. PubMed ID: 10910062
    [Abstract] [Full Text] [Related]

  • 8. LY303511 (2-piperazinyl-8-phenyl-4H-1-benzopyran-4-one) acts via phosphatidylinositol 3-kinase-independent pathways to inhibit cell proliferation via mammalian target of rapamycin (mTOR)- and non-mTOR-dependent mechanisms.
    Kristof AS, Pacheco-Rodriguez G, Schremmer B, Moss J.
    J Pharmacol Exp Ther; 2005 Sep 01; 314(3):1134-43. PubMed ID: 15923340
    [Abstract] [Full Text] [Related]

  • 9. Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation.
    Ghosh PM, Malik SN, Bedolla RG, Wang Y, Mikhailova M, Prihoda TJ, Troyer DA, Kreisberg JI.
    Endocr Relat Cancer; 2005 Mar 01; 12(1):119-34. PubMed ID: 15788644
    [Abstract] [Full Text] [Related]

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  • 11. 4-Hydroxy estradiol but not 2-hydroxy estradiol induces expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor A through phosphatidylinositol 3-kinase/Akt/FRAP pathway in OVCAR-3 and A2780-CP70 human ovarian carcinoma cells.
    Gao N, Nester RA, Sarkar MA.
    Toxicol Appl Pharmacol; 2004 Apr 01; 196(1):124-35. PubMed ID: 15050414
    [Abstract] [Full Text] [Related]

  • 12. Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins.
    Xu Y, Chen SY, Ross KN, Balk SP.
    Cancer Res; 2006 Aug 01; 66(15):7783-92. PubMed ID: 16885382
    [Abstract] [Full Text] [Related]

  • 13. mTOR in renal cell cancer: modulator of tumor biology and therapeutic target.
    Wysocki PJ.
    Expert Rev Mol Diagn; 2009 Apr 01; 9(3):231-41. PubMed ID: 19379082
    [Abstract] [Full Text] [Related]

  • 14. Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.
    Chandrasekher G, Sailaja D.
    Invest Ophthalmol Vis Sci; 2004 Oct 01; 45(10):3577-88. PubMed ID: 15452065
    [Abstract] [Full Text] [Related]

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  • 16. 15(S)-hydroxyeicosatetraenoic acid induces angiogenesis via activation of PI3K-Akt-mTOR-S6K1 signaling.
    Zhang B, Cao H, Rao GN.
    Cancer Res; 2005 Aug 15; 65(16):7283-91. PubMed ID: 16103079
    [Abstract] [Full Text] [Related]

  • 17. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
    Marzec M, Kasprzycka M, Liu X, El-Salem M, Halasa K, Raghunath PN, Bucki R, Wlodarski P, Wasik MA.
    Oncogene; 2007 Aug 16; 26(38):5606-14. PubMed ID: 17353907
    [Abstract] [Full Text] [Related]

  • 18. YC-1 inhibits HIF-1 expression in prostate cancer cells: contribution of Akt/NF-kappaB signaling to HIF-1alpha accumulation during hypoxia.
    Sun HL, Liu YN, Huang YT, Pan SL, Huang DY, Guh JH, Lee FY, Kuo SC, Teng CM.
    Oncogene; 2007 Jun 07; 26(27):3941-51. PubMed ID: 17213816
    [Abstract] [Full Text] [Related]

  • 19. Involvement of the Akt/mTOR pathway on EGF-induced cell transformation.
    Nomura M, He Z, Koyama I, Ma WY, Miyamoto K, Dong Z.
    Mol Carcinog; 2003 Sep 07; 38(1):25-32. PubMed ID: 12949840
    [Abstract] [Full Text] [Related]

  • 20. Regulation of mammalian target of rapamycin activity in PTEN-inactive prostate cancer cells by I kappa B kinase alpha.
    Dan HC, Adli M, Baldwin AS.
    Cancer Res; 2007 Jul 01; 67(13):6263-9. PubMed ID: 17616684
    [Abstract] [Full Text] [Related]

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