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144 related items for PubMed ID: 15161915
1. Inhibition by copper(II) binding of hepatocyte growth factor (HGF) interaction with its receptor Met and blockade of HGF/Met function. Wright TG, Tsai J, Jia Z, Elliott BE. J Biol Chem; 2004 Jul 30; 279(31):32499-506. PubMed ID: 15161915 [Abstract] [Full Text] [Related]
2. Cooperative interaction between alpha- and beta-chains of hepatocyte growth factor on c-Met receptor confers ligand-induced receptor tyrosine phosphorylation and multiple biological responses. Matsumoto K, Kataoka H, Date K, Nakamura T. J Biol Chem; 1998 Sep 04; 273(36):22913-20. PubMed ID: 9722511 [Abstract] [Full Text] [Related]
3. Insights into the structure/function of hepatocyte growth factor/scatter factor from studies with individual domains. Holmes O, Pillozzi S, Deakin JA, Carafoli F, Kemp L, Butler PJ, Lyon M, Gherardi E. J Mol Biol; 2007 Mar 23; 367(2):395-408. PubMed ID: 17258232 [Abstract] [Full Text] [Related]
4. Hairpin loop and second kringle domain are essential sites for heparin binding and biological activity of hepatocyte growth factor. Mizuno K, Inoue H, Hagiya M, Shimizu S, Nose T, Shimohigashi Y, Nakamura T. J Biol Chem; 1994 Jan 14; 269(2):1131-6. PubMed ID: 8288571 [Abstract] [Full Text] [Related]
5. A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist. Tolbert WD, Daugherty J, Gao C, Xie Q, Miranti C, Gherardi E, Vande Woude G, Xu HE. Proc Natl Acad Sci U S A; 2007 Sep 11; 104(37):14592-7. PubMed ID: 17804794 [Abstract] [Full Text] [Related]
6. Mutational analysis and molecular modeling of the N-terminal kringle-containing domain of hepatocyte growth factor identifies amino acid side chains important for interaction with the c-Met receptor. Lokker NA, Presta LG, Godowski PJ. Protein Eng; 1994 Jul 11; 7(7):895-903. PubMed ID: 7971951 [Abstract] [Full Text] [Related]
7. Potent blockade of hepatocyte growth factor-stimulated cell motility, matrix invasion and branching morphogenesis by antagonists of Grb2 Src homology 2 domain interactions. Atabey N, Gao Y, Yao ZJ, Breckenridge D, Soon L, Soriano JV, Burke TR, Bottaro DP. J Biol Chem; 2001 Apr 27; 276(17):14308-14. PubMed ID: 11278639 [Abstract] [Full Text] [Related]
8. Structural and functional basis of the serine protease-like hepatocyte growth factor beta-chain in Met binding and signaling. Kirchhofer D, Yao X, Peek M, Eigenbrot C, Lipari MT, Billeci KL, Maun HR, Moran P, Santell L, Wiesmann C, Lazarus RA. J Biol Chem; 2004 Sep 17; 279(38):39915-24. PubMed ID: 15218027 [Abstract] [Full Text] [Related]
9. The SPRY domain-containing SOCS box protein 1 (SSB-1) interacts with MET and enhances the hepatocyte growth factor-induced Erk-Elk-1-serum response element pathway. Wang D, Li Z, Messing EM, Wu G. J Biol Chem; 2005 Apr 22; 280(16):16393-401. PubMed ID: 15713673 [Abstract] [Full Text] [Related]
10. Dimer Interface in Natural Variant NK1 Is Dispensable for HGF-Dependent Met Receptor Activation. Tahira Y, Sakai K, Sato H, Imamura R, Matsumoto K. Int J Mol Sci; 2021 Aug 26; 22(17):. PubMed ID: 34502141 [Abstract] [Full Text] [Related]
11. Dissociation of heparan sulfate and receptor binding domains of hepatocyte growth factor reveals that heparan sulfate-c-met interaction facilitates signaling. Rubin JS, Day RM, Breckenridge D, Atabey N, Taylor WG, Stahl SJ, Wingfield PT, Kaufman JD, Schwall R, Bottaro DP. J Biol Chem; 2001 Aug 31; 276(35):32977-83. PubMed ID: 11435444 [Abstract] [Full Text] [Related]
12. Noncompetitive inhibition of hepatocyte growth factor-dependent Met signaling by a phage-derived peptide. Tam EM, Runyon ST, Santell L, Quan C, Yao X, Kirchhofer D, Skelton NJ, Lazarus RA. J Mol Biol; 2009 Jan 09; 385(1):79-90. PubMed ID: 18973760 [Abstract] [Full Text] [Related]
13. A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis. Hartmann G, Naldini L, Weidner KM, Sachs M, Vigna E, Comoglio PM, Birchmeier W. Proc Natl Acad Sci U S A; 1992 Dec 01; 89(23):11574-8. PubMed ID: 1280830 [Abstract] [Full Text] [Related]
14. Generation and characterization of a competitive antagonist of human hepatocyte growth factor, HGF/NK1. Lokker NA, Godowski PJ. J Biol Chem; 1993 Aug 15; 268(23):17145-50. PubMed ID: 8349603 [Abstract] [Full Text] [Related]
15. Detection of hepatocyte growth factor (HGF) ligand-c-MET receptor activation in formalin-fixed paraffin embedded specimens by a novel proximity assay. Dua R, Zhang J, Parry G, Penuel E. PLoS One; 2011 Jan 21; 6(1):e15932. PubMed ID: 21283737 [Abstract] [Full Text] [Related]
16. Molecular evolution and domain structure of plasminogen-related growth factors (HGF/SF and HGF1/MSP). Donate LE, Gherardi E, Srinivasan N, Sowdhamini R, Aparicio S, Blundell TL. Protein Sci; 1994 Dec 21; 3(12):2378-94. PubMed ID: 7756992 [Abstract] [Full Text] [Related]
17. Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo. Hartmann G, Prospero T, Brinkmann V, Ozcelik C, Winter G, Hepple J, Batley S, Bladt F, Sachs M, Birchmeier C, Birchmeier W, Gherardi E. Curr Biol; 1998 Jan 29; 8(3):125-34. PubMed ID: 9443912 [Abstract] [Full Text] [Related]
18. Isolation and Characterization of a Chinese Hamster Ovary Heparan Sulfate Cell Mutant Defective in Both Met Receptor Binding and Hepatocyte Growth Factor NK1/Met Signaling. Cao T, Pan J, Li X, He Y, Jiang Y, Chang Y, Zhang Q, Lan Y, Wang H, Jiao W, Tian Z, Zhang L. Cell Physiol Biochem; 2018 Jan 29; 48(4):1480-1491. PubMed ID: 30107380 [Abstract] [Full Text] [Related]
19. A high affinity hepatocyte growth factor-binding site in the immunoglobulin-like region of Met. Basilico C, Arnesano A, Galluzzo M, Comoglio PM, Michieli P. J Biol Chem; 2008 Jul 25; 283(30):21267-77. PubMed ID: 18495663 [Abstract] [Full Text] [Related]
20. Identification of functional domains in the hepatocyte growth factor and its receptor by molecular engineering. Bardelli A, Ponzetto C, Comoglio PM. J Biotechnol; 1994 Sep 30; 37(2):109-22. PubMed ID: 7765452 [Abstract] [Full Text] [Related] Page: [Next] [New Search]