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269 related items for PubMed ID: 15166629

  • 1. New platinum(IV) complex with adamantylamine ligand as a promising anti-cancer drug: comparison of in vitro cytotoxic potential towards A2780/cisR cisplatin-resistant cell line within homologous series of platinum(IV) complexes.
    Turánek J, Kasná A, Záluská D, Neca J, Kvardová V, Knötigová P, Horváth V, SIndlerová L, Kozubík A, Sova P, Kroutil A, Zák F, Mistr A.
    Anticancer Drugs; 2004 Jun; 15(5):537-43. PubMed ID: 15166629
    [Abstract] [Full Text] [Related]

  • 2. High effectiveness of platinum(IV) complex with adamantylamine in overcoming resistance to cisplatin and suppressing proliferation of ovarian cancer cells in vitro.
    Kozubík A, Horváth V, Svihálková-Sindlerová L, Soucek K, Hofmanová J, Sova P, Kroutil A, Zák F, Mistr A, Turánek J.
    Biochem Pharmacol; 2005 Feb 01; 69(3):373-83. PubMed ID: 15652229
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  • 3. Platinum(IV) complex with adamantylamine as nonleaving amine group: synthesis, characterization, and in vitro antitumor activity against a panel of cisplatin-resistant cancer cell lines.
    Zák F, Turánek J, Kroutil A, Sova P, Mistr A, Poulová A, Mikolin P, Zák Z, Kasná A, Záluská D, Neca J, Sindlerová L, Kozubík A.
    J Med Chem; 2004 Jan 29; 47(3):761-3. PubMed ID: 14736257
    [Abstract] [Full Text] [Related]

  • 4. Comparative anti-tumor efficacy of two orally administered platinum(IV) drugs in nude mice bearing human tumor xenografts.
    Sova P, Mistr A, Kroutil A, Zak F, Pouckova P, Zadinova M.
    Anticancer Drugs; 2006 Feb 29; 17(2):201-6. PubMed ID: 16428939
    [Abstract] [Full Text] [Related]

  • 5. Different cell cycle modulation following treatment of human ovarian carcinoma cells with a new platinum(IV) complex vs cisplatin.
    Horváth V, Soucek K, Svihálková-Sindlerová L, Vondrácek J, Blanárová O, Hofmanová J, Sova P, Kozubík A.
    Invest New Drugs; 2007 Oct 29; 25(5):435-43. PubMed ID: 17520175
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  • 6. A comparative study of pharmacokinetics, urinary excretion and tissue distribution of platinum in rats following a single-dose oral administration of two platinum(IV) complexes LA-12 (OC-6-43)-bis(acetato)(1-adamantylamine)amminedichloroplatinum(IV) and satraplatin (OC-6-43)-bis(acetato)amminedichloro(cyclohexylamine)platinum(IV).
    Sova P, Mistr A, Kroutil A, Semerád M, Chlubnová H, Hrusková V, Chládková J, Chládek J.
    Cancer Chemother Pharmacol; 2011 Jun 29; 67(6):1247-56. PubMed ID: 20697713
    [Abstract] [Full Text] [Related]

  • 7. Cytotoxicity, mutagenicity, cellular uptake, DNA and glutathione interactions of lipophilic trans-platinum complexes tethered to 1-adamantylamine.
    Halámiková A, Heringová P, Kaspárková J, Intini FP, Natile G, Nemirovski A, Gibson D, Brabec V.
    J Inorg Biochem; 2008 Jun 29; 102(5-6):1077-89. PubMed ID: 18237783
    [Abstract] [Full Text] [Related]

  • 8. The novel platinum(IV) complex LA-12 induces p53 and p53/47 responses that differ from the related drug, cisplatin.
    Hrstka R, Powell DJ, Kvardova V, Roubalova E, Bourougaa K, Candeias MM, Sova P, Zak F, Fåhraeus R, Vojtĕsek B.
    Anticancer Drugs; 2008 Apr 29; 19(4):369-79. PubMed ID: 18454047
    [Abstract] [Full Text] [Related]

  • 9. Platinum(IV) complex with adamantylamine overcomes intrinsic resistance to cisplatin in ovarian cancer cells.
    Horváth V, Blanárová O, Svihálková-Sindlerová L, Soucek K, Hofmanová J, Sova P, Kroutil A, Fedorocko P, Kozubík A.
    Gynecol Oncol; 2006 Jul 29; 102(1):32-40. PubMed ID: 16364413
    [Abstract] [Full Text] [Related]

  • 10. Studies on two new mixed ligand platinum compounds with a trans-geometry.
    Al-Shuneigat J, Yu JQ, Beale P, Fisher K, Huq F.
    Med Chem; 2010 Sep 29; 6(5):321-8. PubMed ID: 20977416
    [Abstract] [Full Text] [Related]

  • 11. Bis- and Tetrakis(carboxylato)platinum(IV) complexes with mixed axial ligands - synthesis, characterization, and cytotoxicity.
    Hoffmeister BR, Hejl M, Adib-Razavi MS, Jakupec MA, Galanski M, Keppler BK.
    Chem Biodivers; 2015 Apr 29; 12(4):559-74. PubMed ID: 25879501
    [Abstract] [Full Text] [Related]

  • 12. Modulatory effect of axial and equatorial ligands on antitumor activities of trans-1R,2R-diaminocyclohexane platinum(IV) complexes.
    Siddik ZH, al-Baker S, Thai G, Khokhar AR.
    Anticancer Drug Des; 1994 Apr 29; 9(2):139-51. PubMed ID: 8166929
    [Abstract] [Full Text] [Related]

  • 13. Platinum(IV) complex LA-12 exerts higher ability than cisplatin to enhance TRAIL-induced cancer cell apoptosis via stimulation of mitochondrial pathway.
    Jelínková I, Šafaříková B, Vondálová Blanářová O, Skender B, Hofmanová J, Sova P, Moyer MP, Kozubík A, Kolář Z, Ehrmann J, Hyršlová Vaculová A.
    Biochem Pharmacol; 2014 Dec 01; 92(3):415-24. PubMed ID: 25285768
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  • 16. Apoptosis and inhibition of gap-junctional intercellular communication induced by LA-12, a novel hydrophobic platinum(IV) complex.
    Procházka L, Turánek J, Tesarík R, Knotigová P, Polásková P, Andrysík Z, Kozubík A, Zák F, Sova P, Neuzil J, Machala M.
    Arch Biochem Biophys; 2007 Jun 01; 462(1):54-61. PubMed ID: 17466256
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  • 17. Dinuclear platinum complexes with N, N'-bis(aminoalkyl)-1,4-diaminoanthraquinones as linking ligands. Part II. Cellular processing in A2780 cisplatin-resistant human ovarian carcinoma cells: new insights into the mechanism of resistance.
    Kalayda GV, Jansen BA, Molenaar C, Wielaard P, Tanke HJ, Reedijk J.
    J Biol Inorg Chem; 2004 Jun 01; 9(4):414-22. PubMed ID: 15071768
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