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Journal Abstract Search

97 related items for PubMed ID: 15170332

  • 1. Quantitative binding models for CYP2C9 based on benzbromarone analogues.
    Locuson CW, Rock DA, Jones JP.
    Biochemistry; 2004 Jun 08; 43(22):6948-58. PubMed ID: 15170332
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  • 2. A new class of CYP2C9 inhibitors: probing 2C9 specificity with high-affinity benzbromarone derivatives.
    Locuson CW, Wahlstrom JL, Rock DA, Rock DA, Jones JP.
    Drug Metab Dispos; 2003 Jul 08; 31(7):967-71. PubMed ID: 12814975
    [Abstract] [Full Text] [Related]

  • 3. Charge and substituent effects on affinity and metabolism of benzbromarone-based CYP2C19 inhibitors.
    Locuson CW, Suzuki H, Rettie AE, Jones JP.
    J Med Chem; 2004 Dec 30; 47(27):6768-76. PubMed ID: 15615526
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  • 5. CYP2C9 structure-metabolism relationships: substrates, inhibitors, and metabolites.
    Ahlström MM, Ridderström M, Zamora I.
    J Med Chem; 2007 Nov 01; 50(22):5382-91. PubMed ID: 17915853
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  • 9. Role of conserved Asp293 of cytochrome P450 2C9 in substrate recognition and catalytic activity.
    Flanagan JU, McLaughlin LA, Paine MJ, Sutcliffe MJ, Roberts GC, Wolf CR.
    Biochem J; 2003 Mar 15; 370(Pt 3):921-6. PubMed ID: 12482324
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  • 11. Analysis of human cytochrome P450 2C8 substrate specificity using a substrate pharmacophore and site-directed mutants.
    Melet A, Marques-Soares C, Schoch GA, Macherey AC, Jaouen M, Dansette PM, Sari MA, Johnson EF, Mansuy D.
    Biochemistry; 2004 Dec 14; 43(49):15379-92. PubMed ID: 15581350
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  • 12. Probing small-molecule binding to cytochrome P450 2D6 and 2C9: An in silico protocol for generating toxicity alerts.
    Rossato G, Ernst B, Smiesko M, Spreafico M, Vedani A.
    ChemMedChem; 2010 Dec 03; 5(12):2088-101. PubMed ID: 21038340
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  • 13. Predicting drug metabolism: a site of metabolism prediction tool applied to the cytochrome P450 2C9.
    Zamora I, Afzelius L, Cruciani G.
    J Med Chem; 2003 Jun 05; 46(12):2313-24. PubMed ID: 12773036
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  • 15. Generation and evaluation of a CYP2C9 heteroactivation pharmacophore.
    Egnell AC, Eriksson C, Albertson N, Houston B, Boyer S.
    J Pharmacol Exp Ther; 2003 Dec 05; 307(3):878-87. PubMed ID: 14557374
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  • 16. Differential roles of Arg97, Asp293, and Arg108 in enzyme stability and substrate specificity of CYP2C9.
    Dickmann LJ, Locuson CW, Jones JP, Rettie AE.
    Mol Pharmacol; 2004 Apr 05; 65(4):842-50. PubMed ID: 15044613
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  • 17. Identification of cytochrome P450 2D6 and 2C9 substrates and inhibitors by QSAR analysis.
    Jónsdóttir SÓ, Ringsted T, Nikolov NG, Dybdahl M, Wedebye EB, Niemelä JR.
    Bioorg Med Chem; 2012 Mar 15; 20(6):2042-53. PubMed ID: 22364953
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  • 18. Multiple molecular dynamics simulations of human p450 monooxygenase CYP2C9: the molecular basis of substrate binding and regioselectivity toward warfarin.
    Seifert A, Tatzel S, Schmid RD, Pleiss J.
    Proteins; 2006 Jul 01; 64(1):147-55. PubMed ID: 16639745
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  • 19. pH dependency of ligand binding to cellobiohydrolase 1 (Cel7A). Affinity, selectivity and inhibition for designed propranolol analogues.
    Fagerström A, Nilsson M, Berg U, Isaksson R.
    J Chromatogr A; 2007 Jan 05; 1138(1-2):276-83. PubMed ID: 17141791
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