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312 related items for PubMed ID: 15170356

  • 1. Stereospecific alkylation of cis-3-chloroacrylic acid dehalogenase by (R)-oxirane-2-carboxylate: analysis and mechanistic implications.
    Poelarends GJ, Serrano H, Johnson WH, Whitman CP.
    Biochemistry; 2004 Jun 08; 43(22):7187-96. PubMed ID: 15170356
    [Abstract] [Full Text] [Related]

  • 2. The roles of active-site residues in the catalytic mechanism of trans-3-chloroacrylic acid dehalogenase: a kinetic, NMR, and mutational analysis.
    Azurmendi HF, Wang SC, Massiah MA, Poelarends GJ, Whitman CP, Mildvan AS.
    Biochemistry; 2004 Apr 13; 43(14):4082-91. PubMed ID: 15065850
    [Abstract] [Full Text] [Related]

  • 3. Cloning, expression, and characterization of a cis-3-chloroacrylic acid dehalogenase: insights into the mechanistic, structural, and evolutionary relationship between isomer-specific 3-chloroacrylic acid dehalogenases.
    Poelarends GJ, Serrano H, Person MD, Johnson WH, Murzin AG, Whitman CP.
    Biochemistry; 2004 Jan 27; 43(3):759-72. PubMed ID: 14730981
    [Abstract] [Full Text] [Related]

  • 4. Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase. Structural basis for substrate specificity and inactivation by (R)-oxirane-2-carboxylate.
    de Jong RM, Bazzacco P, Poelarends GJ, Johnson WH, Kim YJ, Burks EA, Serrano H, Thunnissen AM, Whitman CP, Dijkstra BW.
    J Biol Chem; 2007 Jan 26; 282(4):2440-9. PubMed ID: 17121835
    [Abstract] [Full Text] [Related]

  • 5. Inactivation of Cg10062, a cis-3-chloroacrylic acid dehalogenase homologue in Corynebacterium glutamicum, by (R)- and (S)-oxirane-2-carboxylate: analysis and implications.
    Robertson BA, Johnson WH, Lo HH, Whitman CP.
    Biochemistry; 2008 Aug 19; 47(33):8796-803. PubMed ID: 18646866
    [Abstract] [Full Text] [Related]

  • 6. Characterization of a newly identified mycobacterial tautomerase with promiscuous dehalogenase and hydratase activities reveals a functional link to a recently diverged cis-3-chloroacrylic acid dehalogenase.
    Baas BJ, Zandvoort E, Wasiel AA, Quax WJ, Poelarends GJ.
    Biochemistry; 2011 Apr 12; 50(14):2889-99. PubMed ID: 21370851
    [Abstract] [Full Text] [Related]

  • 7. Phenylpyruvate tautomerase activity of trans-3-chloroacrylic acid dehalogenase: evidence for an enol intermediate in the dehalogenase reaction?
    Poelarends GJ, Johnson WH, Serrano H, Whitman CP.
    Biochemistry; 2007 Aug 21; 46(33):9596-604. PubMed ID: 17661448
    [Abstract] [Full Text] [Related]

  • 8. Reactions of 4-oxalocrotonate tautomerase and YwhB with 3-halopropiolates: analysis and implications.
    Wang SC, Johnson WH, Czerwinski RM, Whitman CP.
    Biochemistry; 2004 Jan 27; 43(3):748-58. PubMed ID: 14730980
    [Abstract] [Full Text] [Related]

  • 9. Identification of active site residues essential to 4-chlorobenzoyl-coenzyme A dehalogenase catalysis by chemical modification and site directed mutagenesis.
    Yang G, Liu RQ, Taylor KL, Xiang H, Price J, Dunaway-Mariano D.
    Biochemistry; 1996 Aug 20; 35(33):10879-85. PubMed ID: 8718880
    [Abstract] [Full Text] [Related]

  • 10. A mutational analysis of the active site loop residues in cis-3-Chloroacrylic acid dehalogenase.
    Schroeder GK, Huddleston JP, Johnson WH, Whitman CP.
    Biochemistry; 2013 Jun 18; 52(24):4204-16. PubMed ID: 23692140
    [Abstract] [Full Text] [Related]

  • 11. The hydratase activity of malonate semialdehyde decarboxylase: mechanistic and evolutionary implications.
    Poelarends GJ, Serrano H, Johnson WH, Hoffman DW, Whitman CP.
    J Am Chem Soc; 2004 Dec 08; 126(48):15658-9. PubMed ID: 15571384
    [Abstract] [Full Text] [Related]

  • 12. Resolution of the uncertainty in the kinetic mechanism for the trans-3-Chloroacrylic acid dehalogenase-catalyzed reaction.
    Huddleston JP, Wang SC, Johnson KA, Whitman CP.
    Arch Biochem Biophys; 2017 Jun 01; 623-624():9-19. PubMed ID: 28499743
    [Abstract] [Full Text] [Related]

  • 13. Pre-steady-state kinetic analysis of cis-3-chloroacrylic acid dehalogenase: analysis and implications.
    Robertson BA, Schroeder GK, Jin Z, Johnson KA, Whitman CP.
    Biochemistry; 2009 Dec 15; 48(49):11737-44. PubMed ID: 19856961
    [Abstract] [Full Text] [Related]

  • 14. Reactions of trans-3-chloroacrylic acid dehalogenase with acetylene substrates: consequences of and evidence for a hydration reaction.
    Wang SC, Person MD, Johnson WH, Whitman CP.
    Biochemistry; 2003 Jul 29; 42(29):8762-73. PubMed ID: 12873137
    [Abstract] [Full Text] [Related]

  • 15. Inactivation of malonate semialdehyde decarboxylase by 3-halopropiolates: evidence for hydratase activity.
    Poelarends GJ, Serrano H, Johnson WH, Whitman CP.
    Biochemistry; 2005 Jul 05; 44(26):9375-81. PubMed ID: 15982004
    [Abstract] [Full Text] [Related]

  • 16. Reaction of cis-3-chloroacrylic acid dehalogenase with an allene substrate, 2,3-butadienoate: hydration via an enamine.
    Schroeder GK, Johnson WH, Huddleston JP, Serrano H, Johnson KA, Whitman CP.
    J Am Chem Soc; 2012 Jan 11; 134(1):293-304. PubMed ID: 22129074
    [Abstract] [Full Text] [Related]

  • 17. The 4-oxalocrotonate tautomerase- and YwhB-catalyzed hydration of 3E-haloacrylates: implications for the evolution of new enzymatic activities.
    Wang SC, Johnson WH, Whitman CP.
    J Am Chem Soc; 2003 Nov 26; 125(47):14282-3. PubMed ID: 14624569
    [Abstract] [Full Text] [Related]

  • 18. Product catalyzes the deamidation of D145N dehalogenase to produce the wild-type enzyme.
    Xiang H, Dong J, Carey PR, Dunaway-Mariano D.
    Biochemistry; 1999 Mar 30; 38(13):4207-13. PubMed ID: 10194337
    [Abstract] [Full Text] [Related]

  • 19. The 4-oxalocrotonate tautomerase family of enzymes: how nature makes new enzymes using a beta-alpha-beta structural motif.
    Whitman CP.
    Arch Biochem Biophys; 2002 Jun 01; 402(1):1-13. PubMed ID: 12051677
    [Abstract] [Full Text] [Related]

  • 20. The strength of dehalogenase-substrate hydrogen bonding correlates with the rate of Meisenheimer intermediate formation.
    Dong J, Lu X, Wei Y, Luo L, Dunaway-Mariano D, Carey PR.
    Biochemistry; 2003 Aug 12; 42(31):9482-90. PubMed ID: 12899635
    [Abstract] [Full Text] [Related]

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