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194 related items for PubMed ID: 15170389

  • 1. Interaction of the tyrosine phosphatase SHP-2 with Gab2 regulates Rho-dependent activation of the c-fos serum response element by interleukin-2.
    Arnaud M, Mzali R, Gesbert F, Crouin C, Guenzi C, Vermot-Desroches C, Wijdenes J, Courtois G, Bernard O, Bertoglio J.
    Biochem J; 2004 Sep 01; 382(Pt 2):545-56. PubMed ID: 15170389
    [Abstract] [Full Text] [Related]

  • 2. Phosphorylation of Grb2-associated binder 2 on serine 623 by ERK MAPK regulates its association with the phosphatase SHP-2 and decreases STAT5 activation.
    Arnaud M, Crouin C, Deon C, Loyaux D, Bertoglio J.
    J Immunol; 2004 Sep 15; 173(6):3962-71. PubMed ID: 15356145
    [Abstract] [Full Text] [Related]

  • 3. Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells.
    Kim H, Baumann H.
    Mol Cell Biol; 1999 Aug 15; 19(8):5326-38. PubMed ID: 10409724
    [Abstract] [Full Text] [Related]

  • 4. Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules.
    Yamasaki S, Nishida K, Hibi M, Sakuma M, Shiina R, Takeuchi A, Ohnishi H, Hirano T, Saito T.
    J Biol Chem; 2001 Nov 30; 276(48):45175-83. PubMed ID: 11572860
    [Abstract] [Full Text] [Related]

  • 5. Ligation of CD28 stimulates the formation of a multimeric signaling complex involving grb-2-associated binder 2 (gab2), SRC homology phosphatase-2, and phosphatidylinositol 3-kinase: evidence that negative regulation of CD28 signaling requires the gab2 pleckstrin homology domain.
    Parry RV, Whittaker GC, Sims M, Edmead CE, Welham MJ, Ward SG.
    J Immunol; 2006 Jan 01; 176(1):594-602. PubMed ID: 16365455
    [Abstract] [Full Text] [Related]

  • 6. Role of the docking protein Gab2 in beta(1)-integrin signaling pathway-mediated hematopoietic cell adhesion and migration.
    Yu WM, Hawley TS, Hawley RG, Qu CK.
    Blood; 2002 Apr 01; 99(7):2351-9. PubMed ID: 11895767
    [Abstract] [Full Text] [Related]

  • 7. Regulation of interleukin-3-induced substrate phosphorylation and cell survival by SHP-2 (Src-homology protein tyrosine phosphatase 2).
    Wheadon H, Edmead C, Welham MJ.
    Biochem J; 2003 Nov 15; 376(Pt 1):147-57. PubMed ID: 12935294
    [Abstract] [Full Text] [Related]

  • 8. Src homology region 2 (SH2) domain-containing phosphatase-1 dephosphorylates B cell linker protein/SH2 domain leukocyte protein of 65 kDa and selectively regulates c-Jun NH2-terminal kinase activation in B cells.
    Mizuno K, Tagawa Y, Mitomo K, Arimura Y, Hatano N, Katagiri T, Ogimoto M, Yakura H.
    J Immunol; 2000 Aug 01; 165(3):1344-51. PubMed ID: 10903736
    [Abstract] [Full Text] [Related]

  • 9. IL-2, but not IL-4 and other cytokines, induces phosphorylation of a 98-kDa protein associated with SHP-2, phosphatidylinositol 3'-kinase, and Grb2.
    Gadina M, Sudarshan C, O'Shea JJ.
    J Immunol; 1999 Feb 15; 162(4):2081-6. PubMed ID: 9973481
    [Abstract] [Full Text] [Related]

  • 10. Cas mediates transcriptional activation of the serum response element by Src.
    Hakak Y, Martin GS.
    Mol Cell Biol; 1999 Oct 15; 19(10):6953-62. PubMed ID: 10490632
    [Abstract] [Full Text] [Related]

  • 11. Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling.
    Kim SO, Jiang J, Yi W, Feng GS, Frank SJ.
    J Biol Chem; 1998 Jan 23; 273(4):2344-54. PubMed ID: 9442080
    [Abstract] [Full Text] [Related]

  • 12. Role of the Grb2-associated binder 1/SHP-2 interaction in cell growth and transformation.
    Holgado-Madruga M, Wong AJ.
    Cancer Res; 2004 Mar 15; 64(6):2007-15. PubMed ID: 15026337
    [Abstract] [Full Text] [Related]

  • 13. A new tyrosine-phosphorylated 97-kDa adaptor protein mediates interleukin-2-induced association of SHP-2 with p85-phosphatidylinositol 3-kinase in human T lymphocytes.
    Gesbert F, Guenzi C, Bertoglio J.
    J Biol Chem; 1998 Jul 17; 273(29):18273-81. PubMed ID: 9660791
    [Abstract] [Full Text] [Related]

  • 14. A yeast two-hybrid study of human p97/Gab2 interactions with its SH2 domain-containing binding partners.
    Crouin C, Arnaud M, Gesbert F, Camonis J, Bertoglio J.
    FEBS Lett; 2001 Apr 27; 495(3):148-53. PubMed ID: 11334882
    [Abstract] [Full Text] [Related]

  • 15. Noonan syndrome-associated SHP2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activation.
    Fragale A, Tartaglia M, Wu J, Gelb BD.
    Hum Mutat; 2004 Mar 27; 23(3):267-77. PubMed ID: 14974085
    [Abstract] [Full Text] [Related]

  • 16. Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors.
    Nishida K, Yoshida Y, Itoh M, Fukada T, Ohtani T, Shirogane T, Atsumi T, Takahashi-Tezuka M, Ishihara K, Hibi M, Hirano T.
    Blood; 1999 Mar 15; 93(6):1809-16. PubMed ID: 10068651
    [Abstract] [Full Text] [Related]

  • 17. Gab2 is phosphorylated on tyrosine upon interleukin-2/interleukin-15 stimulation in mycosis-fungoides-derived tumor T cells and associates inducibly with SHP-2 and Stat5a.
    Brockdorff JL, Gu H, Mustelin T, Kaltoft K, Geisler C, Röpke C, Ødum N.
    Exp Clin Immunogenet; 2001 Mar 15; 18(2):86-95. PubMed ID: 11340297
    [Abstract] [Full Text] [Related]

  • 18. Recruitment of the protein-tyrosine phosphatase SHP-2 to the C-terminal tyrosine of the prolactin receptor and to the adaptor protein Gab2.
    Ali S, Ali S.
    J Biol Chem; 2000 Dec 15; 275(50):39073-80. PubMed ID: 10991949
    [Abstract] [Full Text] [Related]

  • 19. Role of SHP-2 in fibroblast growth factor receptor-mediated suppression of myogenesis in C2C12 myoblasts.
    Kontaridis MI, Liu X, Zhang L, Bennett AM.
    Mol Cell Biol; 2002 Jun 15; 22(11):3875-91. PubMed ID: 11997521
    [Abstract] [Full Text] [Related]

  • 20. Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules.
    Tanaka S, Ito T, Wands JR.
    J Biol Chem; 1996 Jun 14; 271(24):14610-6. PubMed ID: 8662827
    [Abstract] [Full Text] [Related]

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